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NCT01950390 · ClinicalTrials.gov registry record · Phase 2
Ipilimumab With or Without Bevacizumab in Treating Patients With Stage III-IV Melanoma That Cannot Be Removed by Surgery
A Phase 2 study of Unresectable Melanoma and Stage IV Cutaneous Melanoma AJCC v6 and v7, sponsored by National Cancer Institute (NCI).
- Completed
- Registry status
- Phase 2
- Development phase
- 169
- Enrollment target
- 20
- Study locations
NCT01950390 is a Phase 2 study of Unresectable Melanoma and Stage IV Cutaneous Melanoma AJCC v6 and v7 that has completed, run by National Cancer Institute (NCI). The registered enrollment target is 169 participants, above the 135-participant average among 24 other Unresectable Melanoma trials with a reported enrollment target (25% higher). The trial reports 20 study locations across 4 states.
The verdict
NCT01950390, a Phase 2 study of Unresectable Melanoma and Stage IV Cutaneous Melanoma AJCC v6 and v7, has completed, sponsored by National Cancer Institute (NCI).
- COMPLETED
- Registry status
- Phase 2
- Development phase
- 169 participants
- Enrollment target
- 20
- Study locations
Study Summary
This randomized phase II trial studies how well ipilimumab with or without bevacizumab works in treating patients with stage III-IV melanoma that cannot be removed by surgery. Immunotherapy with monoclonal antibodies, such as ipilimumab and bevacizumab, may help the body's immune system attack the cancer, and may interfere with the ability of tumor cells to grow and spread.
Conditions Studied
Interventions
- BIOLOGICAL Ipilimumab
- BIOLOGICAL Bevacizumab
Study Locations (20)
California
- Kaiser Permanente-Anaheim - Anaheim
- Kaiser Permanente-Baldwin Park - Baldwin Park
- Kaiser Permanente-Bellflower - Bellflower
- Kaiser Permanente-Fontana - Fontana
- Kaiser Permanente South Bay - Harbor City
- Kaiser Permanente-Irvine - Irvine
- Kaiser Permanente Los Angeles Medical Center - Los Angeles
- Kaiser Permanente West Los Angeles - Los Angeles
- Kaiser Permanente - Panorama City - Panorama City
- Kaiser Permanente-Riverside - Riverside
- Kaiser Permanente-San Diego Mission - San Diego
- Kaiser Permanente-San Diego Zion - San Diego
- Kaiser Permanente-San Marcos - San Marcos
- Kaiser Permanente-Woodland Hills - Woodland Hills
Connecticut
- Smilow Cancer Hospital Care Center at Saint Francis - Hartford
- Eastern Connecticut Hematology and Oncology Associates - Norwich
- Stamford Hospital/Bennett Cancer Center - Stamford
Alabama
- University of Alabama at Birmingham Cancer Center - Birmingham
- University of South Alabama Mitchell Cancer Institute - Mobile
Delaware
- Beebe Medical Center - Lewes
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 169 participants |
| Start Date | 2014-01-24 |
| Est. Completion | 2025-01-31 |
| Phase | Phase 2 |
Interested in This Trial?
Full Details on ClinicalTrials.gov ↗What the Registry Record Tells You About NCT01950390
The ClinicalTrials.gov registry entry for NCT01950390 describes a study currently listed as completed, categorized as Phase 2. The registered enrollment target is 169 participants, a figure that helps gauge the scale of data the investigators plan to collect, above the 135-participant average among 24 other Unresectable Melanoma trials with a reported enrollment target (25% higher). The listed sponsor is National Cancer Institute (NCI), which has 3,257 total studies on file at ClinicalTrials.gov.
The record links to 3 conditions, with Unresectable Melanoma appearing as the primary indexed condition, and to 2 interventions - of which Ipilimumab is the first listed.
NCT01950390 reports 20 study locations spanning 4 distinct geographic areas - top geographies include California, Connecticut, Alabama.
Frequently Asked Questions
What is clinical trial NCT01950390 about?
NCT01950390 is a clinical study titled "Ipilimumab With or Without Bevacizumab in Treating Patients With Stage III-IV Melanoma That Cannot Be Removed by Surgery". This randomized phase II trial studies how well ipilimumab with or without bevacizumab works in treating patients with stage III-IV melanoma that cannot be removed by surgery. Immunotherapy with monoclonal antibodies, such as ipilimumab and bevacizumab, may help the body's immune system attack the c...
What is the current status of trial NCT01950390?
This trial is currently completed. It is a Phase 2 study. The enrollment target is 169 participants. The study started on 2014-01-24. Estimated completion is 2025-01-31.
What conditions does trial NCT01950390 study?
This clinical trial studies the following conditions: Unresectable Melanoma, Stage IV Cutaneous Melanoma AJCC v6 and v7, Stage IIIC Cutaneous Melanoma AJCC v7.
What interventions are being tested in trial NCT01950390?
The interventions under investigation include: Ipilimumab (BIOLOGICAL), Bevacizumab (BIOLOGICAL).
Who is sponsoring clinical trial NCT01950390?
This trial is sponsored by National Cancer Institute (NCI), which has 3,257 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT01950390 being conducted?
This trial has 20 study locations across Alabama, California, Connecticut, Delaware. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
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Unresectable Melanoma
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Stage IV Cutaneous Melanoma AJCC v6 and v7
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