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ClinicalTrials.gov 7 recruiting now early-phase tilt small index

Stage III Renal Cell Cancer AJCC v8: early-phase trial registry

7 of 15 indexed Stage III Renal Cell Cancer AJCC v8 trials are currently recruiting, with more weight in Phase 1-2.

Corpus placement: #1,140 of 28,707 conditions by registered trial count.

15 US clinical trials · 7 currently recruiting · #1,140 of 28,707 conditions by registered trial count

Stage III Renal Cell Cancer AJCC v8: 15 US clinical trials tracked, 7 recruiting.

Stage III Renal Cell Cancer AJCC v8 is the subject of 15 registered US clinical trials on ClinicalTrials.gov, 7 of them currently open to new participants. 1 are in Phase 3-4 (later-stage) and 14 in Phase 1-2 (earlier-stage). The most active sponsor is National Cancer Institute (NCI), running 4 of these trials.

Enrollment posture brief

Registry condition stage-iii-renal-cell-cancer-ajcc-v8

OPEN 7 | RECR 47% | LATE 1 | EARLY 14 | RANK #1140 | SPON 4

Nearest open-share peer: Autism (47% recruiting · 105 trials)

Advanced Lung Non-Small Cell53.3%Stage III Renal Cell Can (th…47%AIDS26.7%Adult Acute Myeloid Leukemia0%Adult Glioblastoma0%
Open-enrollment share among volume-matched conditions near Stage III Renal Cell Cancer AJCC v8

Stage III Renal Cell Cancer AJCC v8 lists 7 open slots (47% of 15 indexed trials). Peers are matched on registered volume, not therapeutic-area browse lists. How peer matching works →

Key findings

What ClinicalTrials.gov does not surface for Stage III Renal Cell Cancer AJCC v8 on its own pages , computed from the registry mirror as of 2026-08-08. Each line carries its own denominator so it can be quoted as it stands.

  1. Stage III Renal Cell Cancer AJCC v8 recruits in line with its size-band peers.

    7 of 15 indexed trials (46.7%) are open to enrollment, against a 46.5% average across 27,806 conditions with fewer than 20 trials. The peer set uses the same ClinicalTrials.gov-derived counts as this page.

  2. One sponsor concentrates Stage III Renal Cell Cancer AJCC v8 research.

    National Cancer Institute (NCI) accounts for 4 of 15 trials (26.7%). 9 distinct sponsors appear on at least one study for this condition label.

  3. Most Stage III Renal Cell Cancer AJCC v8 trials plan to enrol fewer than 100 people.

    Median target enrolment is 54 among the 15 trials that report a genuine target (sentinel values excluded). 13 of those (86.7%) plan for fewer than 100 participants.

  4. Stage III Renal Cell Cancer AJCC v8 research is mostly interventional.

    15 interventional and 0 observational studies make up this index (100% interventional). Study type is sponsor-reported on ClinicalTrials.gov.

Phase 15Phase 29Phase 31

Open and recent trials

15 total, page 1 of 1

RECRUITING Phase 2 240 participants

Testing the Addition of Stereotactic Radiation Therapy With Immune Therapy for the Treatment of Patients With Unresectable or Metastatic Renal Cell Cancer, SAMURAI Trial

NRG Oncology

NCT05327686

RECRUITING Phase 2 65 participants

Testing of Bevacizumab, Erlotinib, and Atezolizumab in Combination for Advanced-Stage Kidney Cancer

National Cancer Institute (NCI)

NCT04981509

RECRUITING Phase 1 56 participants

Imaging of Solid Tumors Using 18F-TRX

Rahul Aggarwal

NCT06942104

RECRUITING Phase 1 55 participants

Inulin Gel in Combination With Ipilimumab and Nivolumab for the Treatment of Metastatic or Locally Advanced Kidney Cell Cancer, ICON Trial

University of Michigan Rogel Cancer Center

NCT06866262

RECRUITING Phase 2 54 participants

Genetic Testing to Select Therapy for the Treatment of Advanced or Metastatic Kidney Cancer, OPTIC RCC Study

Vanderbilt-Ingram Cancer Center

NCT05361720

RECRUITING Phase 1 33 participants

Immunotherapy (Nivolumab and Ipilimumab) With and Without a Live Biotherapeutic Product (EXL01) for the Treatment of Metastatic Renal Cell Cancer

City of Hope Medical Center

NCT07128680

RECRUITING Phase 1 28 participants

CBM588 Capsules in Combination With Nivolumab and Ipilimumab for the Treatment of Advanced Stage Kidney Cancer

Osel

NCT06399419

ACTIVE NOT RECRUITING Phase 3 1,175 participants

Immunotherapy With Nivolumab and Ipilimumab Followed by Nivolumab or Nivolumab With Cabozantinib for Patients With Advanced Kidney Cancer, The PDIGREE Study

National Cancer Institute (NCI)

NCT03793166

ACTIVE NOT RECRUITING Phase 2 90 participants

Lenvatinib With Everolimus Versus Cabozantinib for Second-Line or Third-Line Treatment of Metastatic Renal Cell Cancer

M.D. Anderson Cancer Center

NCT05012371

ACTIVE NOT RECRUITING Phase 2 60 participants

Testing AZD1775 in Advanced Solid Tumors That Have a Mutation Called SETD2

National Cancer Institute (NCI)

NCT03284385

ACTIVE NOT RECRUITING Phase 1 31 participants

CBM588 in Combination With Nivolumab and Cabozantinib for the Treatment of Advanced or Metastatic Kidney Cancer

City of Hope Medical Center

NCT05122546

ACTIVE NOT RECRUITING Phase 2 30 participants

Ixazomib, Gemcitabine, and Doxorubicin in Treating Patients With Locally Advanced or Metastatic Kidney Cancer

M.D. Anderson Cancer Center

NCT03587662

ACTIVE NOT RECRUITING Phase 2 22 participants

Neoadjuvant Cabozantinib in Treating Patients With Locally Advanced Kidney Cancer

Emory University

NCT04022343

ACTIVE NOT RECRUITING Phase 2 18 participants

Perioperative Lenvatinib With Pembrolizumab in Patients With Locally Advanced Nonmetastatic Clear Cell Renal Cell Carcinoma

Emory University

NCT04393350

ACTIVE NOT RECRUITING Phase 2 15 participants

A Study to Compare Treatments for a Type of Kidney Cancer Called TFE/Translocation Renal Cell Carcinoma (tRCC)

National Cancer Institute (NCI)

NCT03595124

Phase Distribution

PhaseTrial count
Phase 1 5
Phase 2 9
Phase 3 1

Named interventions

Most-linked intervention names on Stage III Renal Cell Cancer AJCC v8 records (sponsor-reported on ClinicalTrials.gov). Counts are trial links, not unique products.

Biospecimen Collection Procedure
6 trials
Ipilimumab Biological
5 trials
Cabozantinib Drug
5 trials
Bone Scan Procedure
5 trials
Computed Tomography Procedure
4 trials
Nivolumab Biological
3 trials
Axitinib Drug
2 trials
Lenvatinib Drug
2 trials

US sites by state

Facility locations filed on Stage III Renal Cell Cancer AJCC v8 trials. A trial with sites in several states counts in each.

California 10 trials
Texas 4 trials
Georgia 3 trials
Arkansas 3 trials
Alabama 3 trials
Ohio 2 trials
Michigan 2 trials
Maryland 2 trials

Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.

What to do with this Stage III Renal Cell Cancer AJCC v8 page

15 registered trials, 7 currently recruiting, is a starting point for a conversation, not a diagnosis or a recommendation.

Trial and recruiting counts reflect ClinicalTrials.gov registry status as of the data vintage above; individual trial eligibility and enrollment status can change.

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This Stage III Renal Cell Cancer AJCC v8 condition card totals 15 registered trials; most-linked intervention Biospecimen Collection; top US site state California. See our editorial standards & corrections policy, the methodology behind these numbers, the data changelog, or report a data error.