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Stage I Prostate Cancer AJCC v8: early-phase trial registry
11 of 21 indexed Stage I Prostate Cancer AJCC v8 trials are currently recruiting, with more weight in Phase 1-2.
Corpus placement: #797 of 28,707 conditions by registered trial count.
21 US clinical trials · 11 currently recruiting · #797 of 28,707 conditions by registered trial count
Stage I Prostate Cancer AJCC v8: 21 US clinical trials tracked, 11 recruiting.
Stage I Prostate Cancer AJCC v8 is the subject of 21 registered US clinical trials on ClinicalTrials.gov, 11 of them currently open to new participants. 3 are in Phase 3-4 (later-stage) and 7 in Phase 1-2 (earlier-stage). The most active sponsor is M.D. Anderson Cancer Center, running 5 of these trials.
Enrollment posture brief
Registry condition stage-i-prostate-cancer-ajcc-v8
OPEN 11 | RECR 52% | LATE 3 | EARLY 7 | RANK #797 | SPON 5
Volume-matched condition peers
Nearest open-share peer: End-Stage Kidney Disease (52% recruiting · 21 trials)
Stage I Prostate Cancer AJCC v8 lists 11 open slots (52% of 21 indexed trials). Peers are matched on registered volume, not therapeutic-area browse lists. How peer matching works →
Key findings
What ClinicalTrials.gov does not surface for Stage I Prostate Cancer AJCC v8 on its own pages , computed from the registry mirror as of 2026-08-08. Each line carries its own denominator so it can be quoted as it stands.
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Stage I Prostate Cancer AJCC v8 is recruiting above its size-band peers.
11 of 21 indexed trials (52.4%) are open to enrollment, against a 39.7% average across 762 conditions with 20-99 trials. The peer set uses the same ClinicalTrials.gov-derived counts as this page.
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One sponsor concentrates Stage I Prostate Cancer AJCC v8 research.
M.D. Anderson Cancer Center accounts for 5 of 21 trials (23.8%). 12 distinct sponsors appear on at least one study for this condition label.
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Typical Stage I Prostate Cancer AJCC v8 enrolment sits around 80 participants.
Median target enrolment is 80 among the 21 trials that report a genuine target (sentinel values excluded). 12 of those (57.1%) plan for fewer than 100 participants.
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Stage I Prostate Cancer AJCC v8 research is mostly interventional.
20 interventional and 1 observational studies make up this index (95.2% interventional). Study type is sponsor-reported on ClinicalTrials.gov.
Open and recent trials
21 total, page 1 of 1
Testing the Addition of the Drug Apalutamide to the Usual Hormone Therapy and Radiation Therapy After Surgery for Prostate Cancer, INNOVATE Trial
NRG Oncology
NCT04134260
Vitamin D for Prostate Endocrine Therapy
University of Rochester
NCT05838716
Image-Guidance and Online Adaptation With Stereotactic Body Radiation Therapy for the Treatment of Localized Prostate Cancer, MANTICORE Trial
Jonsson Comprehensive Cancer Center
NCT07276438
Adaptive Radiation Therapy (ART) Stereotactic Ablative Body Radiotherapy (SABR) for Primary Localized Prostate Cancer
Mayo Clinic
NCT06325046
Focal Ablation With Focal Cryotherapy or HIFU for the Treatment of Men With Localized Prostate Cancer
Marc Dall'Era, MD
NCT06178354
MRI-guided Transurethral Urethral Ultrasound Ablation for the Treatment of Low to Intermediate Grade Prostate Cancer
Mayo Clinic
NCT05438563
Computed Tomography-Guided Stereotactic Body Radiation Therapy With Intrafraction Motion Monitoring for the Treatment of Localized Prostate Cancer, ILLUSION Trial
Jonsson Comprehensive Cancer Center
NCT06995053
Time-Restricted Eating Versus Nutritional Counseling for the Reduction of Radiation or Chemoradiation Tx Side Effects in Patients With Prostate, Cervical, or Rectal Cancers
City of Hope Medical Center
NCT05722288
Accuracy of 18F-rhPSMA-7.3 PET/ MRI for Prediction of Lymph Node Metastasis in Localized High-Risk Prostate Cancer
Mayo Clinic
NCT06389786
rhPSMA-73 PET-MRI Imaging for the Detection of Prostate Cancer Among Men Who Are Otherwise Candidates for Active Surveillance
Northwestern University
NCT05852041
Feasibility and Effect of Wrapping Nerves With a Multi-Layer Perinatal Tissue Allograft During Prostatectomy
Mayo Clinic
NCT06940271
Lifestyle Behavior Influences Among African American Patients With Stage 0-III Prostate Cancer Survivors and Their Partners
M.D. Anderson Cancer Center
NCT04189770
Conventional or Hypofractionated Radiation Therapy in Treating Patients With Prostate Cancer
M.D. Anderson Cancer Center
NCT03987386
White Button Mushroom Sup for the Reduction of PSA in Pts With Biochemically Rec or Therapy Naive Fav Risk Prostate CA
City of Hope Medical Center
NCT04519879
RElugolix VErsus LeUprolide Cardiac Trial
Emory University
NCT05320406
Watchful Living in Improving Quality of Life in Participants With Localized Prostate Cancer on Active Surveillance and Their Partners
M.D. Anderson Cancer Center
NCT03575832
Testing the Effects of Low Dose Apalutamide on Prostate-Specific Antigen (PSA) Levels in Men Scheduled for Removal of the Prostate Gland
National Cancer Institute (NCI)
NCT04530552
Comparison of High-Dose Rate Brachytherapy and Stereotactic Ablative Radiotherapy as Monotherapy for the Treatment of Localized Prostate Cancer
Rutgers, The State University of New Jersey
NCT04253483
Neoadjuvant Dietary Intervention in Intermediate Risk Prostate Cancer
M.D. Anderson Cancer Center
NCT04985565
Aspirin and Rintatolimod With or Without Interferon-alpha 2b in Treating Patients With Prostate Cancer Before Surgery
Roswell Park Cancer Institute
NCT03899987
Lifestyle Intervention for the Reduction of Prostate Cancer Disparities Among African Americans
M.D. Anderson Cancer Center
NCT04215029
Phase Distribution
| Phase | Trial count |
|---|---|
| Phase 1 | 1 |
| Phase 2 | 6 |
| Phase 3 | 3 |
Top Sponsors
Named interventions
Most-linked intervention names on Stage I Prostate Cancer AJCC v8 records (sponsor-reported on ClinicalTrials.gov). Counts are trial links, not unique products.
US sites by state
Facility locations filed on Stage I Prostate Cancer AJCC v8 trials. A trial with sites in several states counts in each.
Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.
Related
What to do with this Stage I Prostate Cancer AJCC v8 page
21 registered trials, 11 currently recruiting, is a starting point for a conversation, not a diagnosis or a recommendation.
- 11 Stage I Prostate Cancer AJCC v8 trials are currently recruiting, check eligibility criteria before contacting a site. Browse recruiting trials
- M.D. Anderson Cancer Center sponsors the most Stage I Prostate Cancer AJCC v8 trials on record, review their full trial history before evaluating a specific study. See M.D. Anderson Cancer Center's trials
- Bring the specific trial ID (NCT number) to your own doctor before enrolling, this page is a directory, not medical guidance. Read the trial-finding guide
Trial and recruiting counts reflect ClinicalTrials.gov registry status as of the data vintage above; individual trial eligibility and enrollment status can change.
Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This Stage I Prostate Cancer AJCC v8 condition card totals 21 registered trials; most-linked intervention Questionnaire Administration; top US site state California. See our editorial standards & corrections policy, the methodology behind these numbers, the data changelog, or report a data error.