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ClinicalTrials.gov 7 recruiting now full pipeline small index

Spasticity, Muscle: full-pipeline trial registry

7 of 12 indexed Spasticity, Muscle trials are currently recruiting.

Corpus placement: #1,429 of 28,707 conditions by registered trial count.

12 US clinical trials · 7 currently recruiting · #1,429 of 28,707 conditions by registered trial count

Spasticity, Muscle: 12 US clinical trials tracked, 7 recruiting.

Spasticity, Muscle is the subject of 12 registered US clinical trials on ClinicalTrials.gov, 7 of them currently open to new participants. 1 are in Phase 3-4 (later-stage) and 1 in Phase 1-2 (earlier-stage). The most active sponsor is Medical University of South Carolina, running 2 of these trials.

Enrollment posture brief

Registry condition spasticity-muscle

OPEN 7 | RECR 58% | LATE 1 | EARLY 1 | RANK #1429 | SPON 2

Nearest open-share peer: Anterior Cruciate Ligament Reconstruction (58% recruiting · 12 trials)

Spasticity, Muscle (this)58%Acute Myeloid Leukemia in Re41.7%Adenocarcinoma of the Rectum41.7%Adherence, Patient16.7%Accelerated Phase Chronic My0%
Open-enrollment share among volume-matched conditions near Spasticity, Muscle

Spasticity, Muscle lists 7 open slots (58% of 12 indexed trials). Peers are matched on registered volume, not therapeutic-area browse lists. How peer matching works →

Key findings

What ClinicalTrials.gov does not surface for Spasticity, Muscle on its own pages , computed from the registry mirror as of 2026-08-08. Each line carries its own denominator so it can be quoted as it stands.

  1. Spasticity, Muscle is recruiting above its size-band peers.

    7 of 12 indexed trials (58.3%) are open to enrollment, against a 46.5% average across 27,806 conditions with fewer than 20 trials. The peer set uses the same ClinicalTrials.gov-derived counts as this page.

  2. One sponsor concentrates Spasticity, Muscle research.

    Medical University of South Carolina accounts for 2 of 12 trials (16.7%). 10 distinct sponsors appear on at least one study for this condition label.

  3. Most Spasticity, Muscle trials plan to enrol fewer than 100 people.

    Median target enrolment is 30 among the 12 trials that report a genuine target (sentinel values excluded). 9 of those (75%) plan for fewer than 100 participants.

  4. Spasticity, Muscle splits between interventional and observational designs.

    8 interventional and 4 observational studies make up this index (66.7% interventional). Study type is sponsor-reported on ClinicalTrials.gov.

Phase 11Phase 31

Open and recent trials

12 total, page 1 of 1

RECRUITING 200 participants

Hereditary Spastic Paraplegia Genomic Sequencing Initiative (HSPseq)

Boston Children's Hospital

NCT05354622

RECRUITING NA 30 participants

Extracorporeal Shockwave Therapy for Spasticity in People With Spinal Cord Injury

Kessler Foundation

NCT05432999

RECRUITING NA 28 participants

Activating Spinal Circuits to Improve Walking, Balance, Strength, and Reduce Spasticity

Shepherd Center, Atlanta GA

NCT05429736

RECRUITING NA 25 participants

Operant Conditioning of Spinal Reflexes Training System--Reflex Operant Down Conditioning

Medical University of South Carolina

NCT05094362

RECRUITING NA 22 participants

Radiosurgery Treatment for Spasticity Associated With Stroke, SCI & Cerebral Palsy

Ohio State University

NCT06070233

RECRUITING NA 12 participants

Transcutaneous Spinal Stimulation for Lower Limb Spasticity in Spinal Cord Injury

University of Mississippi Medical Center

NCT05457205

RECRUITING Phase 1 4 participants

Melpida: Recombinant Adeno-associated Virus (serotype 9) Encoding a Codon Optimized Human AP4M1 Transgene (hAP4M1opt)

Elpida Therapeutics SPC

NCT05518188

COMPLETED Phase 3 323 participants

A Study to Evaluate the Long-term Safety of Arbaclofen Extended-Release Tablets for Patients With Spasticity Due to MS

RVL Pharmaceuticals

NCT03319732

COMPLETED 105 participants

Efficacy and Safety of 10-Week or Shorter vs 12-Week or Longer Injection Intervals of Botulinum Toxin

University of Texas Southwestern Medical Center

NCT05103202

COMPLETED 60 participants

Validity and Inter-Rater Reliability of a Novel Bedside Referral Tool for Spasticity

Vanderbilt University Medical Center

NCT03209960

COMPLETED 60 participants

Using Telemedicine to Improve Spasticity Diagnosis Rates

Vanderbilt University Medical Center

NCT03211390

COMPLETED NA 11 participants

DDN in Stroke--COBRE

Medical University of South Carolina

NCT05196737

Phase Distribution

PhaseTrial count
Phase 1 1
Phase 3 1

Named interventions

Most-linked intervention names on Spasticity, Muscle records (sponsor-reported on ClinicalTrials.gov). Counts are trial links, not unique products.

Teleneurological Examination Diagnostic test
1 trials
Neurological Examination Diagnostic test
1 trials
Neurological Examination Other
1 trials
Bedside Referral Tool Diagnostic test
1 trials
Arbaclofen Drug
1 trials
Dry Needling Behavioral
1 trials
Extracorporeal Shockwave Therapy Device
1 trials
Transcutaneous Spinal Stimulation (TSS) Device
1 trials

US sites by state

Facility locations filed on Spasticity, Muscle trials. A trial with sites in several states counts in each.

Texas 2 trials
Tennessee 2 trials
South Carolina 2 trials
Ohio 1 trials
New Jersey 1 trials
Mississippi 1 trials
Massachusetts 1 trials
Georgia 1 trials

Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.

What to do with this Spasticity, Muscle page

12 registered trials, 7 currently recruiting, is a starting point for a conversation, not a diagnosis or a recommendation.

Trial and recruiting counts reflect ClinicalTrials.gov registry status as of the data vintage above; individual trial eligibility and enrollment status can change.

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This Spasticity, Muscle condition card totals 12 registered trials; most-linked intervention Teleneurological Examination; top US site state Texas. See our editorial standards & corrections policy, the methodology behind these numbers, the data changelog, or report a data error.