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ClinicalTrials.gov 11 recruiting now official registry

Solid Tumor Malignancies clinical trials

11 of 12 indexed Solid Tumor Malignancies trials are currently recruiting.

12 US clinical trials · 11 currently recruiting

Solid Tumor Malignancies is the subject of 12 registered US clinical trials on ClinicalTrials.gov, 11 of them currently open to new participants. 2 are in Phase 3-4 (later-stage) and 8 in Phase 1-2 (earlier-stage). The most active sponsor is Kumquat Biosciences, running 3 of these trials.

The research picture

Solid Tumor Malignancies has 12 registered US clinical trials, 11 of them open to new participants right now, about 92% of the total.

11
recruiting participants now
92%
of trials open to enrollment
2
in Phase 3–4 (later-stage)
3
top sponsor: Kumquat Biosciences
Phase 18Phase 31Phase 41

Active & Recent Trials

12 total, page 1 of 1

RECRUITING NA 500 participants

PROGRESS: Precision Oncology Using Genomic Reflexive Evaluations for Study Selection and Survival

UNC Lineberger Comprehensive Cancer Center

NCT06896162

RECRUITING Phase 1 450 participants

Safety and Preliminary Efficacy of VIR-5525 and VIR-5525 + Pembrolizumab in Participants With Locally Advanced or Metastatic Solid Tumors

Vir Biotechnology

NCT06960395

RECRUITING NA 210 participants

xDRIVE for Florida-based Cancer Patients

First Ascent Biomedical

NCT07167381

RECRUITING Phase 1 200 participants

A Study to Evaluate the Safety, Pharmacokinetics and Efficacy of TJ101 in Patients With Advanced/Metastatic Solid Tumors

Phrontline Biopharma

NCT07181473

RECRUITING Phase 3 192 participants

Trial to Evaluate irAEs With Different Standard of Care Dosing Strategies of Standard of Care Immunotherapies

University of Kansas Medical Center

NCT07174453

RECRUITING Phase 1 150 participants

Study of CP-383 in Patients With Advanced or Metastatic Solid Tumors

Tasca Therapeutics

NCT07030257

RECRUITING Phase 1 128 participants

A Study to Investigate the Safety and Efficacy of KQB365 as Monotherapy and in Combination in Participants With Advanced Solid Malignancies

Kumquat Biosciences

NCT06720987

RECRUITING Phase 1 86 participants

A First-In-Human, Phase 1 Study Evaluating Oral TACC3 PPI Inhibitor, AO-252, in Advanced Solid Tumors With or Without Brain Metastases

A2A Pharmaceuticals

NCT06136884

RECRUITING Phase 1 84 participants

A Study to Investigate the Safety and Efficacy of KQB168 as Monotherapy and in Combination in Participants With Advanced Solid Malignancies

Kumquat Biosciences

NCT06994806

RECRUITING Phase 1 78 participants

A Study to Investigate the Safety and Efficacy of KQB548 in Participants With Advanced Solid Malignancies

Kumquat Biosciences

NCT07207707

RECRUITING Phase 4 16 participants

Olutasidenib DDI Study in Patients With IDH1 Mutation Positive Malignancies

Rigel Pharmaceuticals

NCT07486713

ACTIVE NOT RECRUITING Phase 1 58 participants

ProAgio in Previously Treated Advanced Pancreatic Cancer and Other Solid Tumor Malignancies

ProDa BioTech

NCT05085548

Phase Distribution

PhaseTrial count
Phase 1 8
Phase 3 1
Phase 4 1

Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.

Reading the Solid Tumor Malignancies Trial Landscape

12 indexed Solid Tumor Malignancies studies · 11 recruiting (92%).

Phase mix: 2 late (III/IV) vs 8 early (I/II).

Top sponsor: Kumquat Biosciences (3 trials), 9 others listed. 12 shown below, recruiting first.

How to read this condition's trial landscape

That ratio is a useful proxy for activity level: a high share of recruiting studies often signals that research interest is current and that new enrollment opportunities are appearing, while a low share typically means the field is dominated by completed or follow-up work where most participant spots have already been filled. These counts reflect the public registry only and include studies at every stage of design, so they should be read as an index of research attention rather than as a measure of treatment availability.

Phase 1 and Phase 2 studies focus on early safety signals, dosing, and preliminary effect, while Phase 3 studies are typically the larger efficacy and safety trials submitted toward regulatory review, and Phase 4 studies follow approved interventions in real-world use. A condition weighted toward later phases often reflects a mature research pipeline with several interventions already close to or past approval, whereas a heavier early-phase tilt suggests the field is still exploring new mechanisms and candidate approaches.

All figures are derived from the public ClinicalTrials.gov dataset maintained by the National Library of Medicine and are reproduced here for reference. Inclusion of a trial, sponsor, or intervention on this page is neither an endorsement nor a recommendation, eligibility, protocol changes, and site-level status can shift frequently, so always verify current details on ClinicalTrials.gov and consult a qualified healthcare provider before acting on anything you see here.

Frequently Asked Questions

How many clinical trials are there for Solid Tumor Malignancies?

PlainTrial tracks 12 US clinical trials for Solid Tumor Malignancies, of which 11 are currently recruiting participants. Data sourced from ClinicalTrials.gov.

How do I find a recruiting trial for Solid Tumor Malignancies?

Use the trial list above filtered by "Recruiting" status, or visit our trial finder at /recruiting to search by condition and state. Always discuss trial participation with your healthcare provider before enrolling.

Is this data current?

Data is sourced from ClinicalTrials.gov and reflects our most recent data pull. Trial status may have changed since then. Always verify current information at ClinicalTrials.gov before making decisions about participation.

Disclaimer: This information is provided for informational purposes only and does not constitute professional advice. Data is sourced from ClinicalTrials.gov (National Library of Medicine). Consult a qualified professional before making decisions based on this data.

Source: ClinicalTrials.gov (NIH/NLM) ClinicalTrials.gov AACT registry · 2026 Trial counts and statuses sourced from ClinicalTrials.gov. Sponsor counts include both industry and federal/academic sponsors.

Verify with NIH →

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page aggregates every registered trial for this condition, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.