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ClinicalTrials.gov 11 recruiting now early-phase tilt small index

Solid Tumor Malignancies: early-phase trial registry

11 of 12 indexed Solid Tumor Malignancies trials are currently recruiting, with more weight in Phase 1-2.

Corpus placement: #1,429 of 28,707 conditions by registered trial count.

12 US clinical trials · 11 currently recruiting · #1,429 of 28,707 conditions by registered trial count

Solid Tumor Malignancies: 12 US clinical trials tracked, 11 recruiting.

Solid Tumor Malignancies is the subject of 12 registered US clinical trials on ClinicalTrials.gov, 11 of them currently open to new participants. 2 are in Phase 3-4 (later-stage) and 8 in Phase 1-2 (earlier-stage). The most active sponsor is Kumquat Biosciences, running 3 of these trials.

Enrollment posture brief

Registry condition solid-tumor-malignancies

OPEN 11 | RECR 92% | LATE 2 | EARLY 8 | RANK #1429 | SPON 3

Nearest open-share peer: Spinal Cord Injury Cervical (92% recruiting · 13 trials)

Solid Tumor Malignancies (th…92%Acute Myeloid Leukemia in Re41.7%Adenocarcinoma of the Rectum41.7%Adherence, Patient16.7%Accelerated Phase Chronic My0%
Open-enrollment share among volume-matched conditions near Solid Tumor Malignancies

Solid Tumor Malignancies lists 11 open slots (92% of 12 indexed trials). Peers are matched on registered volume, not therapeutic-area browse lists. How peer matching works →

Key findings

What ClinicalTrials.gov does not surface for Solid Tumor Malignancies on its own pages , computed from the registry mirror as of 2026-08-08. Each line carries its own denominator so it can be quoted as it stands.

  1. Solid Tumor Malignancies is recruiting above its size-band peers.

    11 of 12 indexed trials (91.7%) are open to enrollment, against a 46.5% average across 27,806 conditions with fewer than 20 trials. The peer set uses the same ClinicalTrials.gov-derived counts as this page.

  2. One sponsor concentrates Solid Tumor Malignancies research.

    Kumquat Biosciences accounts for 3 of 12 trials (25%). 10 distinct sponsors appear on at least one study for this condition label.

  3. Typical Solid Tumor Malignancies enrolment sits around 150 participants.

    Median target enrolment is 150 among the 12 trials that report a genuine target (sentinel values excluded). 5 of those (41.7%) plan for fewer than 100 participants.

  4. Solid Tumor Malignancies research is mostly interventional.

    12 interventional and 0 observational studies make up this index (100% interventional). Study type is sponsor-reported on ClinicalTrials.gov.

Phase 18Phase 31Phase 41

Open and recent trials

12 total, page 1 of 1

RECRUITING NA 500 participants

PROGRESS: Precision Oncology Using Genomic Reflexive Evaluations for Study Selection and Survival

UNC Lineberger Comprehensive Cancer Center

NCT06896162

RECRUITING Phase 1 450 participants

Safety and Preliminary Efficacy of VIR-5525 and VIR-5525 + Pembrolizumab in Participants With Locally Advanced or Metastatic Solid Tumors

Vir Biotechnology

NCT06960395

RECRUITING NA 210 participants

xDRIVE for Florida-based Cancer Patients

First Ascent Biomedical

NCT07167381

RECRUITING Phase 1 200 participants

A Study to Evaluate the Safety, Pharmacokinetics and Efficacy of TJ101 in Patients With Advanced/Metastatic Solid Tumors

Phrontline Biopharma

NCT07181473

RECRUITING Phase 3 192 participants

Trial to Evaluate irAEs With Different Standard of Care Dosing Strategies of Standard of Care Immunotherapies

University of Kansas Medical Center

NCT07174453

RECRUITING Phase 1 150 participants

Study of CP-383 in Patients With Advanced or Metastatic Solid Tumors

Tasca Therapeutics

NCT07030257

RECRUITING Phase 1 128 participants

A Study to Investigate the Safety and Efficacy of KQB365 as Monotherapy and in Combination in Participants With Advanced Solid Malignancies

Kumquat Biosciences

NCT06720987

RECRUITING Phase 1 86 participants

A First-In-Human, Phase 1 Study Evaluating Oral TACC3 PPI Inhibitor, AO-252, in Advanced Solid Tumors With or Without Brain Metastases

A2A Pharmaceuticals

NCT06136884

RECRUITING Phase 1 84 participants

A Study to Investigate the Safety and Efficacy of KQB168 as Monotherapy and in Combination in Participants With Advanced Solid Malignancies

Kumquat Biosciences

NCT06994806

RECRUITING Phase 1 78 participants

A Study to Investigate the Safety and Efficacy of KQB548 in Participants With Advanced Solid Malignancies

Kumquat Biosciences

NCT07207707

RECRUITING Phase 4 16 participants

Olutasidenib DDI Study in Patients With IDH1 Mutation Positive Malignancies

Rigel Pharmaceuticals

NCT07486713

ACTIVE NOT RECRUITING Phase 1 58 participants

ProAgio in Previously Treated Advanced Pancreatic Cancer and Other Solid Tumor Malignancies

ProDa BioTech

NCT05085548

Phase Distribution

PhaseTrial count
Phase 1 8
Phase 3 1
Phase 4 1

Named interventions

Most-linked intervention names on Solid Tumor Malignancies records (sponsor-reported on ClinicalTrials.gov). Counts are trial links, not unique products.

Pembrolizumab Drug
3 trials
ProAgio Dose Levels 4a,5a,6a Drug
1 trials
ProAgio Dose Levels (DL) 4,5,6 Drug
1 trials
ProAgio Dose Levels (DL) 1,2,3 Drug
1 trials
KQB365 Drug
1 trials
KQB168 Drug
1 trials
xDRIVE Tumor Profiling Diagnostic test
1 trials
CP-383 Drug
1 trials

US sites by state

Facility locations filed on Solid Tumor Malignancies trials. A trial with sites in several states counts in each.

Texas 7 trials
Florida 6 trials
Virginia 5 trials
Ohio 4 trials
Michigan 4 trials
Colorado 4 trials
California 3 trials
Arizona 3 trials

Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.

What to do with this Solid Tumor Malignancies page

12 registered trials, 11 currently recruiting, is a starting point for a conversation, not a diagnosis or a recommendation.

  • 11 Solid Tumor Malignancies trials are currently recruiting, check eligibility criteria before contacting a site. Browse recruiting trials
  • Kumquat Biosciences sponsors the most Solid Tumor Malignancies trials on record, review their full trial history before evaluating a specific study. See Kumquat Biosciences's trials
  • Bring the specific trial ID (NCT number) to your own doctor before enrolling, this page is a directory, not medical guidance. Read the trial-finding guide

Trial and recruiting counts reflect ClinicalTrials.gov registry status as of the data vintage above; individual trial eligibility and enrollment status can change.

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This Solid Tumor Malignancies condition card totals 12 registered trials; most-linked intervention Pembrolizumab; top US site state Texas. See our editorial standards & corrections policy, the methodology behind these numbers, the data changelog, or report a data error.