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ClinicalTrials.gov 48 recruiting now early-phase tilt

Solid Tumor, Adult: early-phase trial registry

48 of 73 indexed Solid Tumor, Adult trials are currently recruiting, with more weight in Phase 1-2.

Corpus placement: #188 of 28,707 conditions by registered trial count.

73 US clinical trials · 48 currently recruiting · #188 of 28,707 conditions by registered trial count

Solid Tumor, Adult: 73 US clinical trials tracked, 48 recruiting.

Solid Tumor, Adult is the subject of 73 registered US clinical trials on ClinicalTrials.gov, 48 of them currently open to new participants. 0 are in Phase 3-4 (later-stage) and 61 in Phase 1-2 (earlier-stage). The most active sponsor is Memorial Sloan Kettering Cancer Center, running 7 of these trials.

Enrollment posture brief

Registry condition solid-tumor-adult

OPEN 48 | RECR 66% | LATE 0 | EARLY 61 | RANK #188 | SPON 7

Nearest open-share peer: Hematopoietic and Lymphoid System Neoplasm (66% recruiting · 32 trials)

Solid Tumor, Adult (this)66%Anatomic Stage II Breast Can54.1%Pulmonary Hypertension50.7%Contraception21.9%Anemia18.9%
Open-enrollment share among volume-matched conditions near Solid Tumor, Adult

Solid Tumor, Adult lists 48 open slots (66% of 73 indexed trials). Peers are matched on registered volume, not therapeutic-area browse lists. How peer matching works →

Key findings

What ClinicalTrials.gov does not surface for Solid Tumor, Adult on its own pages , computed from the registry mirror as of 2026-08-08. Each line carries its own denominator so it can be quoted as it stands.

  1. Solid Tumor, Adult is recruiting above its size-band peers.

    48 of 73 indexed trials (65.8%) are open to enrollment, against a 39.7% average across 762 conditions with 20-99 trials. The peer set uses the same ClinicalTrials.gov-derived counts as this page.

  2. Sponsorship of Solid Tumor, Adult trials is spread across many organizations.

    Memorial Sloan Kettering Cancer Center accounts for 7 of 73 trials (9.6%). 60 distinct sponsors appear on at least one study for this condition label.

  3. Typical Solid Tumor, Adult enrolment sits around 115 participants.

    Median target enrolment is 115 among the 73 trials that report a genuine target (sentinel values excluded). 32 of those (43.8%) plan for fewer than 100 participants.

  4. Solid Tumor, Adult research is mostly interventional.

    69 interventional and 4 observational studies make up this index (94.5% interventional). Study type is sponsor-reported on ClinicalTrials.gov.

Phase 157Phase 24

Open and recent trials

73 total, page 2 of 2

ACTIVE NOT RECRUITING Phase 1 310 participants

Safety and Preliminary Anti-Tumor Activity of TYRA-300 in Advanced Urothelial Carcinoma and Other Solid Tumors With FGFR3 Gene Alterations

Tyra Biosciences

NCT05544552

ACTIVE NOT RECRUITING Phase 1 292 participants

First-in-Human Study of ICT01 in Patients With Advanced Cancer

ImCheck Therapeutics

NCT04243499

ACTIVE NOT RECRUITING Phase 1 180 participants

Study to Evaluate D-1553 in Subjects With Solid Tumors

InventisBio Co.

NCT04585035

ACTIVE NOT RECRUITING Phase 1 160 participants

A Study to Evaluate the Safety and Efficacy of A2B530, a Logic-gated CAR T, in Participants With Solid Tumors That Express CEA and Have Lost HLA-A*02 Expression

A2 Biotherapeutics

NCT05736731

ACTIVE NOT RECRUITING Phase 1 130 participants

Study of CBX-12 in Subjects With Advanced or Metastatic Refractory Solid Tumors

Cybrexa Therapeutics

NCT04902872

ACTIVE NOT RECRUITING Phase 1 120 participants

Study of DECOY20 With or Without Tislelizumab in Patients With Advanced Solid Tumors

Indaptus Therapeutics

NCT05651022

ACTIVE NOT RECRUITING Phase 1 115 participants

Nous-209 Genetic Vaccine for the Treatment of Microsatellite Unstable Solid Tumors

Nouscom SRL

NCT04041310

ACTIVE NOT RECRUITING Phase 1 98 participants

A Study of SNS-101 (Anti VISTA) Monotherapy and in Combination With Cemiplimab in Patients With Advanced Solid Tumors

Sensei Biotherapeutics

NCT05864144

ACTIVE NOT RECRUITING Phase 1 77 participants

A Study of HST-1011 Given as Monotherapy and in Combination With an Anti-PD1 Antibody

HotSpot Therapeutics

NCT05662397

ACTIVE NOT RECRUITING Phase 1 56 participants

Evaluation of AL3818 in Combination With Nivolumab in Solid Tumors

Sarcoma Oncology Research Center

NCT04165330

ACTIVE NOT RECRUITING Phase 1 54 participants

A Study of AZD1390 and Stereotactic Body Radiotherapy (SBRT) for People With Metastatic Solid Tumor Cancer

Memorial Sloan Kettering Cancer Center

NCT05678010

ACTIVE NOT RECRUITING Phase 1 52 participants

A Study to Assess AXN-2510 Treatment in Adult Patients With Advanced Solid Tumors

Axion Bio

NCT07159828

ACTIVE NOT RECRUITING Phase 2 51 participants

Study of Benralizumab in People With Skin Side Effects Caused by Cancer Therapies

Memorial Sloan Kettering Cancer Center

NCT04552288

ACTIVE NOT RECRUITING Phase 1 42 participants

A Monotherapy in Subjects With Advanced Solid Tumors

3D Medicines (Beijing) Co.

NCT04221204

ACTIVE NOT RECRUITING Phase 1 2 participants

A Rollover Study for Subjects Who Completed Participation in IMSA101-101 Trial

ImmuneSensor Therapeutics

NCT06026254

COMPLETED Phase 1 78 participants

A Phase 1a/b Study of IK-175 as a Single Agent and in Combination With Nivolumab in Patients With Locally Advanced or Metastatic Solid Tumors and Urothelial Carcinoma

Ikena Oncology

NCT04200963

COMPLETED Phase 2 52 participants

Pembrolizumab Activity in Patients With Homologous Recombination Competent and Deficient Tumors

Baptist Health South Florida

NCT03274661

COMPLETED Phase 1 52 participants

A Study to Evaluate NT219 Alone and in Combination with ERBITUX® (Cetuximab) in Adults with Advanced Solid Tumors and Head and Neck Cancer

TyrNovo

NCT04474470

COMPLETED Phase 1 41 participants

First-in-Human Study of RLY-5836 in Advanced Breast Cancer and Other Solid Tumors

Relay Therapeutics

NCT05759949

COMPLETED 27 participants

Cannabis Use in Cancer Patients

University of Colorado, Denver

NCT03617692

COMPLETED Phase 1 26 participants

A Study of DCR-STAT3 in Adults With Solid Tumors

Dicerna Pharmaceuticals, Inc., a Novo Nordisk company

NCT06098651

COMPLETED Phase 1 22 participants

Study of FCN-437c in Patients With Advanced Solid Tumors

Fochon Pharmaceuticals

NCT03951116

COMPLETED Phase 1 19 participants

18F-FDG Uptake Measurements in Malignant Solid Tumors on PET/CT and PET/MR

Washington University School of Medicine

NCT02717572

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Phase Distribution

PhaseTrial count
Phase 1 57
Phase 2 4

Named interventions

Most-linked intervention names on Solid Tumor, Adult records (sponsor-reported on ClinicalTrials.gov). Counts are trial links, not unique products.

Fulvestrant Drug
4 trials
Pre-assessment questionnaire Behavioral
2 trials
Meaning Centered Psychotherapy for Latinos for Waitlist Control Patients Behavioral
2 trials
Functional Assessment of Cancer Therapy - Spiritual Well-Being Scale Behavioral
2 trials
Meaning Centered Psychotherapy for Latinos Behavioral
2 trials
Ribociclib Drug
2 trials
Abemaciclib Drug
2 trials
Nivolumab Drug
2 trials

US sites by state

Facility locations filed on Solid Tumor, Adult trials. A trial with sites in several states counts in each.

California 39 trials
New York 35 trials
Texas 34 trials
Florida 27 trials
Tennessee 20 trials
Pennsylvania 16 trials
Massachusetts 16 trials
Michigan 14 trials

Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.

What to do with this Solid Tumor, Adult page

73 registered trials, 48 currently recruiting, is a starting point for a conversation, not a diagnosis or a recommendation.

Trial and recruiting counts reflect ClinicalTrials.gov registry status as of the data vintage above; individual trial eligibility and enrollment status can change.

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This Solid Tumor, Adult condition card totals 73 registered trials; most-linked intervention Fulvestrant; top US site state California. See our editorial standards & corrections policy, the methodology behind these numbers, the data changelog, or report a data error.