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ClinicalTrials.gov 48 recruiting now official registry

Solid Tumor, Adult clinical trials

48 of 73 indexed Solid Tumor, Adult trials are currently recruiting.

73 US clinical trials · 48 currently recruiting

Solid Tumor, Adult is the subject of 73 registered US clinical trials on ClinicalTrials.gov, 48 of them currently open to new participants. 0 are in Phase 3-4 (later-stage) and 61 in Phase 1-2 (earlier-stage). The most active sponsor is Memorial Sloan Kettering Cancer Center, running 7 of these trials.

The research picture

Solid Tumor, Adult has 73 registered US clinical trials, 48 of them open to new participants right now, about 66% of the total.

48
recruiting participants now
66%
of trials open to enrollment
0
in Phase 3–4 (later-stage)
7
top sponsor: Memorial Sloan Kettering Cancer Center
Phase 157Phase 24

Active & Recent Trials

73 total, page 2 of 2

ACTIVE NOT RECRUITING Phase 1 310 participants

Safety and Preliminary Anti-Tumor Activity of TYRA-300 in Advanced Urothelial Carcinoma and Other Solid Tumors With FGFR3 Gene Alterations

Tyra Biosciences

NCT05544552

ACTIVE NOT RECRUITING Phase 1 292 participants

First-in-Human Study of ICT01 in Patients With Advanced Cancer

ImCheck Therapeutics

NCT04243499

ACTIVE NOT RECRUITING Phase 1 180 participants

Study to Evaluate D-1553 in Subjects With Solid Tumors

InventisBio Co.

NCT04585035

ACTIVE NOT RECRUITING Phase 1 160 participants

A Study to Evaluate the Safety and Efficacy of A2B530, a Logic-gated CAR T, in Participants With Solid Tumors That Express CEA and Have Lost HLA-A*02 Expression

A2 Biotherapeutics

NCT05736731

ACTIVE NOT RECRUITING Phase 1 130 participants

Study of CBX-12 in Subjects With Advanced or Metastatic Refractory Solid Tumors

Cybrexa Therapeutics

NCT04902872

ACTIVE NOT RECRUITING Phase 1 120 participants

Study of DECOY20 With or Without Tislelizumab in Patients With Advanced Solid Tumors

Indaptus Therapeutics

NCT05651022

ACTIVE NOT RECRUITING Phase 1 115 participants

Nous-209 Genetic Vaccine for the Treatment of Microsatellite Unstable Solid Tumors

Nouscom SRL

NCT04041310

ACTIVE NOT RECRUITING Phase 1 98 participants

A Study of SNS-101 (Anti VISTA) Monotherapy and in Combination With Cemiplimab in Patients With Advanced Solid Tumors

Sensei Biotherapeutics

NCT05864144

ACTIVE NOT RECRUITING Phase 1 77 participants

A Study of HST-1011 Given as Monotherapy and in Combination With an Anti-PD1 Antibody

HotSpot Therapeutics

NCT05662397

ACTIVE NOT RECRUITING Phase 1 56 participants

Evaluation of AL3818 in Combination With Nivolumab in Solid Tumors

Sarcoma Oncology Research Center

NCT04165330

ACTIVE NOT RECRUITING Phase 1 54 participants

A Study of AZD1390 and Stereotactic Body Radiotherapy (SBRT) for People With Metastatic Solid Tumor Cancer

Memorial Sloan Kettering Cancer Center

NCT05678010

ACTIVE NOT RECRUITING Phase 1 52 participants

A Study to Assess AXN-2510 Treatment in Adult Patients With Advanced Solid Tumors

Axion Bio

NCT07159828

ACTIVE NOT RECRUITING Phase 2 51 participants

Study of Benralizumab in People With Skin Side Effects Caused by Cancer Therapies

Memorial Sloan Kettering Cancer Center

NCT04552288

ACTIVE NOT RECRUITING Phase 1 42 participants

A Monotherapy in Subjects With Advanced Solid Tumors

3D Medicines (Beijing) Co.

NCT04221204

ACTIVE NOT RECRUITING Phase 1 2 participants

A Rollover Study for Subjects Who Completed Participation in IMSA101-101 Trial

ImmuneSensor Therapeutics

NCT06026254

COMPLETED Phase 1 78 participants

A Phase 1a/b Study of IK-175 as a Single Agent and in Combination With Nivolumab in Patients With Locally Advanced or Metastatic Solid Tumors and Urothelial Carcinoma

Ikena Oncology

NCT04200963

COMPLETED Phase 2 52 participants

Pembrolizumab Activity in Patients With Homologous Recombination Competent and Deficient Tumors

Baptist Health South Florida

NCT03274661

COMPLETED Phase 1 52 participants

A Study to Evaluate NT219 Alone and in Combination with ERBITUX® (Cetuximab) in Adults with Advanced Solid Tumors and Head and Neck Cancer

TyrNovo

NCT04474470

COMPLETED Phase 1 41 participants

First-in-Human Study of RLY-5836 in Advanced Breast Cancer and Other Solid Tumors

Relay Therapeutics

NCT05759949

COMPLETED 27 participants

Cannabis Use in Cancer Patients

University of Colorado, Denver

NCT03617692

COMPLETED Phase 1 26 participants

A Study of DCR-STAT3 in Adults With Solid Tumors

Dicerna Pharmaceuticals, Inc., a Novo Nordisk company

NCT06098651

COMPLETED Phase 1 22 participants

Study of FCN-437c in Patients With Advanced Solid Tumors

Fochon Pharmaceuticals

NCT03951116

COMPLETED Phase 1 19 participants

18F-FDG Uptake Measurements in Malignant Solid Tumors on PET/CT and PET/MR

Washington University School of Medicine

NCT02717572

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Phase Distribution

PhaseTrial count
Phase 1 57
Phase 2 4

Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.

Reading the Solid Tumor, Adult Trial Landscape

73 indexed Solid Tumor, Adult studies · 48 recruiting (66%).

Phase mix: 0 late (III/IV) vs 61 early (I/II).

Top sponsor: Memorial Sloan Kettering Cancer Center (7 trials), 9 others listed. 23 shown below, recruiting first.

How to read this condition's trial landscape

That ratio is a useful proxy for activity level: a high share of recruiting studies often signals that research interest is current and that new enrollment opportunities are appearing, while a low share typically means the field is dominated by completed or follow-up work where most participant spots have already been filled. These counts reflect the public registry only and include studies at every stage of design, so they should be read as an index of research attention rather than as a measure of treatment availability.

Phase 1 and Phase 2 studies focus on early safety signals, dosing, and preliminary effect, while Phase 3 studies are typically the larger efficacy and safety trials submitted toward regulatory review, and Phase 4 studies follow approved interventions in real-world use. A condition weighted toward later phases often reflects a mature research pipeline with several interventions already close to or past approval, whereas a heavier early-phase tilt suggests the field is still exploring new mechanisms and candidate approaches.

All figures are derived from the public ClinicalTrials.gov dataset maintained by the National Library of Medicine and are reproduced here for reference. Inclusion of a trial, sponsor, or intervention on this page is neither an endorsement nor a recommendation, eligibility, protocol changes, and site-level status can shift frequently, so always verify current details on ClinicalTrials.gov and consult a qualified healthcare provider before acting on anything you see here.

Frequently Asked Questions

How many clinical trials are there for Solid Tumor, Adult?

PlainTrial tracks 73 US clinical trials for Solid Tumor, Adult, of which 48 are currently recruiting participants. Data sourced from ClinicalTrials.gov.

How do I find a recruiting trial for Solid Tumor, Adult?

Use the trial list above filtered by "Recruiting" status, or visit our trial finder at /recruiting to search by condition and state. Always discuss trial participation with your healthcare provider before enrolling.

Is this data current?

Data is sourced from ClinicalTrials.gov and reflects our most recent data pull. Trial status may have changed since then. Always verify current information at ClinicalTrials.gov before making decisions about participation.

Disclaimer: This information is provided for informational purposes only and does not constitute professional advice. Data is sourced from ClinicalTrials.gov (National Library of Medicine). Consult a qualified professional before making decisions based on this data.

Source: ClinicalTrials.gov (NIH/NLM) ClinicalTrials.gov AACT registry · 2026 Trial counts and statuses sourced from ClinicalTrials.gov. Sponsor counts include both industry and federal/academic sponsors.

Verify with NIH →

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page aggregates every registered trial for this condition, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.