Medical Information Only. Consult your healthcare provider before considering clinical trial enrollment.
Sleep Deprivation
Open-data reference.
35 US clinical trials · 19 currently recruiting
Active & Recent Trials
Caffeine Optimization Versus Standard Caffeine Dosage (2B-2)
University of Arizona
NCT05588934
Reestablishing Sleep and Circadian Alignment in Medical Intensive Care Unit (MICU) Patients Via a Mechanistic RCT of an Sleep Chronobundle
Yale University
NCT05551325
Nighttime Synchrony of Your Nutrition and Circadian Health
University of Utah
NCT07329283
The Function of Biphasic Sleep in Infants
University of Massachusetts, Amherst
NCT06399939
Menstrual-phase-dependent Differences in Response to Sleep Loss
Brigham and Women's Hospital
NCT05381532
Cardiovascular Risk and Circadian Misalignment in Short Sleepers - Role of Extended Eating Period
Pennington Biomedical Research Center
NCT06070194
The Effect of Sleep Deprivation and Recovery Sleep on Emotional Memory and Affective Reactivity
Beth Israel Deaconess Medical Center
NCT03767426
Mind After Midnight
University of Arizona
NCT07438912
The Effect of Sleep Loss on Emotion Regulation
Beth Israel Deaconess Medical Center
NCT05393830
Effect of Sleep Extension on Ceramides in People with Overweight and Obesity
University of Utah
NCT06180837
Immune Status After Being on Call for 24 Hrs
University of Chicago
NCT06636318
Resilience to Sleep Deprivation and Changes in Sleep Architecture in Shoonya Meditators
Beth Israel Deaconess Medical Center
NCT05026541
Ketone Conferred Resiliency Against Sleep Restriction With Nutritional Intervention.
Ohio State University
NCT06075914
Strategies to Augment Ketosis: Ketone Conferred Resiliency Against Sleep Restriction
Ohio State University
NCT05519644
The Dream Team: Testing Implementation of a Sleep Intervention for Perinatal Women Delivered by Direct Care Workers
Rhode Island Hospital
NCT06737055
Biomarkers of Increased Free Living Sleep Time
University of Utah
NCT04214184
Acoustic Stimulation During Restricted Sleep After Sleep Deprivation
Walter Reed Army Institute of Research (WRAIR)
NCT05309473
Transcranial Electrical Stimulation (TES) at Slow Oscillation (SO) Frequency During NREM Sleep
U.S. Army Medical Research and Development Command
NCT02945501
Sleep and Metabolism
Oregon Health and Science University
NCT05775627
Understanding Sleep in Hospitalized Older Patients
University of Chicago
NCT01057823
Impact of Sleep Workshops in College Students
NYU Langone Health
NCT02665247
Mechanisms of Sleep Disruption Hyperalgesia
Johns Hopkins University
NCT01794689
Does Nightly Dexmedetomidine Improve Sleep and Reduce Delirium in ICU Patients?
Maisonneuve-Rosemont Hospital
NCT01791296
Impact of Bed Provision and Sleep Education
Saint Joseph's University, Philadelphia
NCT04536766
A Study of the Effectiveness and Efficacy of the PowerSleep Device
Philips Respironics
NCT03162328
Olfactory Decision-making and Deprived Sleep
Northwestern University
NCT05093413
Are Bright Lights and Regulated Sleep Effective Treatment for Depression?
New York State Psychiatric Institute
NCT03010488
Sleep Chatbot Intervention for Emerging Black/African American Adults
University of Delaware
NCT05956886
Effect of Total Sleep Deprivation on Vascular Function
University of Florida
NCT04535219
Quantifying and Developing Countermeasures for the Effect of Fatigue-Related Stressors on Automation Use and Trust During Robotic Supervisory Control
Brigham and Women's Hospital
NCT02755493
Implementing Behavioral Sleep Intervention in Urban Primary Care
Children's Hospital of Philadelphia
NCT04046341
Biomarkers of Insufficient Sleep and Sleepiness
University of Colorado, Boulder
NCT03130803
Circadian Rhythm Disruption Effects on Smoke Inhalation
University of Montana
NCT04955431
Sleep Restriction and Postprandial Lipemia
University of Missouri-Columbia
NCT05713370
White Noise to Improve Sleep in the Medical Intensive Care Unit (MICU): a Pilot and Feasibility Study
Yale University
NCT03755011
Phase Distribution
| Phase | Trial count |
|---|---|
| Phase 4 | 1 |
Top Sponsors
Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.
Reading the Sleep Deprivation Trial Landscape
ClinicalTrials.gov lists 35 US studies indexed under Sleep Deprivation, and 19 of those are currently open to recruitment — roughly 54% of the total volume on the registry. That ratio is a useful proxy for activity level: a high share of recruiting studies often signals that research interest is current and that new enrollment opportunities are appearing, while a low share typically means the field is dominated by completed or follow-up work where most participant spots have already been filled. These counts reflect the public registry only and include studies at every stage of design, so they should be read as an index of research attention rather than as a measure of treatment availability.
The phase distribution for Sleep Deprivation shows 1 late-stage studies (Phase 3 and Phase 4 combined) alongside 0 earlier-phase entries (Phase 1 through Phase 2). Phase 1 and Phase 2 studies focus on early safety signals, dosing, and preliminary effect, while Phase 3 studies are typically the larger efficacy and safety trials submitted toward regulatory review, and Phase 4 studies follow approved interventions in real-world use. A condition weighted toward later phases often reflects a mature research pipeline with several interventions already close to or past approval, whereas a heavier early-phase tilt suggests the field is still exploring new mechanisms and candidate approaches.
Top sponsor activity for Sleep Deprivation is led by University of Utah with 3 indexed trials, alongside 9 other organizations in the top contributor list. The list on this page surfaces up to 35 of the most relevant recent and active entries, ordered with recruiting studies first so practical options are visible. All figures are derived from the public ClinicalTrials.gov dataset maintained by the National Library of Medicine and are reproduced here for reference. Inclusion of a trial, sponsor, or intervention on this page is neither an endorsement nor a recommendation — eligibility, protocol changes, and site-level status can shift frequently, so always verify current details on ClinicalTrials.gov and consult a qualified healthcare provider before acting on anything you see here.
Frequently Asked Questions
How many clinical trials are there for Sleep Deprivation?
PlainTrial tracks 35 US clinical trials for Sleep Deprivation, of which 19 are currently recruiting participants. Data sourced from ClinicalTrials.gov.
How do I find a recruiting trial for Sleep Deprivation?
Use the trial list above filtered by "Recruiting" status, or visit our trial finder at /recruiting to search by condition and state. Always discuss trial participation with your healthcare provider before enrolling.
Is this data current?
Data is sourced from ClinicalTrials.gov and reflects our most recent data pull. Trial status may have changed since then. Always verify current information at ClinicalTrials.gov before making decisions about participation.
Related
Disclaimer: This information is provided for informational purposes only and does not constitute professional advice. Data is sourced from ClinicalTrials.gov (National Library of Medicine). Consult a qualified professional before making decisions based on this data.
Read our methodology — how this data is sourced, computed, and verified.
Source: ClinicalTrials.gov (NIH/NLM) ClinicalTrials.gov AACT registry · 2024 Trial counts and statuses sourced from ClinicalTrials.gov. Sponsor counts include both industry and federal/academic sponsors.