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ClinicalTrials.gov 19 recruiting now later-stage tilt

Sleep Deprivation: later-stage trial registry

19 of 35 indexed Sleep Deprivation trials are currently recruiting, with more weight in Phase 3-4.

Corpus placement: #435 of 28,707 conditions by registered trial count.

35 US clinical trials · 19 currently recruiting · #435 of 28,707 conditions by registered trial count

Sleep Deprivation: 35 US clinical trials tracked, 19 recruiting.

Sleep Deprivation is the subject of 35 registered US clinical trials on ClinicalTrials.gov, 19 of them currently open to new participants. 1 are in Phase 3-4 (later-stage) and 0 in Phase 1-2 (earlier-stage). The most active sponsor is University of Utah, running 3 of these trials.

Enrollment posture brief

Registry condition sleep-deprivation

OPEN 19 | RECR 54% | LATE 1 | EARLY 0 | RANK #435 | SPON 3

Nearest open-share peer: Non-Hodgkin Lymphoma (54% recruiting · 107 trials)

Cannabis Use Disorder71.4%Cirrhosis, Liver60%Sleep Deprivation (this)54%Carcinoma, Renal Cell17.1%Advanced Lymphoma8.6%
Open-enrollment share among volume-matched conditions near Sleep Deprivation

Sleep Deprivation lists 19 open slots (54% of 35 indexed trials). Peers are matched on registered volume, not therapeutic-area browse lists. How peer matching works →

Key findings

What ClinicalTrials.gov does not surface for Sleep Deprivation on its own pages , computed from the registry mirror as of 2026-08-08. Each line carries its own denominator so it can be quoted as it stands.

  1. Sleep Deprivation is recruiting above its size-band peers.

    19 of 35 indexed trials (54.3%) are open to enrollment, against a 39.7% average across 762 conditions with 20-99 trials. The peer set uses the same ClinicalTrials.gov-derived counts as this page.

  2. Sponsorship of Sleep Deprivation trials is spread across many organizations.

    University of Utah accounts for 3 of 35 trials (8.6%). 26 distinct sponsors appear on at least one study for this condition label.

  3. Most Sleep Deprivation trials plan to enrol fewer than 100 people.

    Median target enrolment is 60 among the 35 trials that report a genuine target (sentinel values excluded). 24 of those (68.6%) plan for fewer than 100 participants.

  4. Sleep Deprivation research is mostly interventional.

    33 interventional and 2 observational studies make up this index (94.3% interventional). Study type is sponsor-reported on ClinicalTrials.gov.

Phase 41

Open and recent trials

35 total, page 1 of 1

RECRUITING NA 180 participants

Caffeine Optimization Versus Standard Caffeine Dosage (2B-2)

University of Arizona

NCT05588934

RECRUITING NA 160 participants

Reestablishing Sleep and Circadian Alignment in Medical Intensive Care Unit (MICU) Patients Via a Mechanistic RCT of an Sleep Chronobundle

Yale University

NCT05551325

RECRUITING NA 120 participants

Nighttime Synchrony of Your Nutrition and Circadian Health

University of Utah

NCT07329283

RECRUITING NA 100 participants

The Function of Biphasic Sleep in Infants

University of Massachusetts, Amherst

NCT06399939

RECRUITING NA 100 participants

Menstrual-phase-dependent Differences in Response to Sleep Loss

Brigham and Women's Hospital

NCT05381532

RECRUITING NA 100 participants

Cardiovascular Risk and Circadian Misalignment in Short Sleepers - Role of Extended Eating Period

Pennington Biomedical Research Center

NCT06070194

RECRUITING NA 100 participants

The Effect of Sleep Deprivation and Recovery Sleep on Emotional Memory and Affective Reactivity

Beth Israel Deaconess Medical Center

NCT03767426

RECRUITING NA 90 participants

Mind After Midnight

University of Arizona

NCT07438912

RECRUITING NA 90 participants

The Effect of Sleep Loss on Emotion Regulation

Beth Israel Deaconess Medical Center

NCT05393830

RECRUITING NA 70 participants

Effect of Sleep Extension on Ceramides in People with Overweight and Obesity

University of Utah

NCT06180837

RECRUITING 60 participants

Immune Status After Being on Call for 24 Hrs

University of Chicago

NCT06636318

RECRUITING NA 60 participants

Resilience to Sleep Deprivation and Changes in Sleep Architecture in Shoonya Meditators

Beth Israel Deaconess Medical Center

NCT05026541

RECRUITING NA 60 participants

Ketone Conferred Resiliency Against Sleep Restriction With Nutritional Intervention.

Ohio State University

NCT06075914

RECRUITING NA 60 participants

Strategies to Augment Ketosis: Ketone Conferred Resiliency Against Sleep Restriction

Ohio State University

NCT05519644

RECRUITING NA 55 participants

The Dream Team: Testing Implementation of a Sleep Intervention for Perinatal Women Delivered by Direct Care Workers

Rhode Island Hospital

NCT06737055

RECRUITING NA 46 participants

Biomarkers of Increased Free Living Sleep Time

University of Utah

NCT04214184

RECRUITING NA 44 participants

Acoustic Stimulation During Restricted Sleep After Sleep Deprivation

Walter Reed Army Institute of Research (WRAIR)

NCT05309473

RECRUITING NA 40 participants

Transcranial Electrical Stimulation (TES) at Slow Oscillation (SO) Frequency During NREM Sleep

U.S. Army Medical Research and Development Command

NCT02945501

RECRUITING NA 20 participants

Sleep and Metabolism

Oregon Health and Science University

NCT05775627

COMPLETED 771 participants

Understanding Sleep in Hospitalized Older Patients

University of Chicago

NCT01057823

COMPLETED NA 180 participants

Impact of Sleep Workshops in College Students

NYU Langone Health

NCT02665247

COMPLETED NA 100 participants

Mechanisms of Sleep Disruption Hyperalgesia

Johns Hopkins University

NCT01794689

COMPLETED Phase 4 100 participants

Does Nightly Dexmedetomidine Improve Sleep and Reduce Delirium in ICU Patients?

Maisonneuve-Rosemont Hospital

NCT01791296

COMPLETED NA 90 participants

Impact of Bed Provision and Sleep Education

Saint Joseph's University, Philadelphia

NCT04536766

COMPLETED NA 84 participants

A Study of the Effectiveness and Efficacy of the PowerSleep Device

Philips Respironics

NCT03162328

COMPLETED NA 46 participants

Olfactory Decision-making and Deprived Sleep

Northwestern University

NCT05093413

COMPLETED NA 44 participants

Are Bright Lights and Regulated Sleep Effective Treatment for Depression?

New York State Psychiatric Institute

NCT03010488

COMPLETED NA 24 participants

Sleep Chatbot Intervention for Emerging Black/African American Adults

University of Delaware

NCT05956886

COMPLETED NA 23 participants

Effect of Total Sleep Deprivation on Vascular Function

University of Florida

NCT04535219

COMPLETED NA 22 participants

Quantifying and Developing Countermeasures for the Effect of Fatigue-Related Stressors on Automation Use and Trust During Robotic Supervisory Control

Brigham and Women's Hospital

NCT02755493

COMPLETED NA 15 participants

Implementing Behavioral Sleep Intervention in Urban Primary Care

Children's Hospital of Philadelphia

NCT04046341

COMPLETED NA 12 participants

Biomarkers of Insufficient Sleep and Sleepiness

University of Colorado, Boulder

NCT03130803

COMPLETED NA 10 participants

Circadian Rhythm Disruption Effects on Smoke Inhalation

University of Montana

NCT04955431

COMPLETED NA 10 participants

Sleep Restriction and Postprandial Lipemia

University of Missouri-Columbia

NCT05713370

COMPLETED NA 7 participants

White Noise to Improve Sleep in the Medical Intensive Care Unit (MICU): a Pilot and Feasibility Study

Yale University

NCT03755011

Phase Distribution

PhaseTrial count
Phase 4 1

Named interventions

Most-linked intervention names on Sleep Deprivation records (sponsor-reported on ClinicalTrials.gov). Counts are trial links, not unique products.

Sleep Restriction Behavioral
3 trials
Sleep deprivation Behavioral
2 trials
Assigned Sleep Times Behavioral
1 trials
Morning Light Therapy Behavioral
1 trials
white noise Device
1 trials
PowerSleep Sham Device
1 trials
PowerSleep Stim Device
1 trials
high fat meal Dietary supplement
1 trials

US sites by state

Facility locations filed on Sleep Deprivation trials. A trial with sites in several states counts in each.

Massachusetts 7 trials
Maryland 4 trials
Utah 3 trials
Pennsylvania 3 trials
Illinois 3 trials
Ohio 2 trials
New York 2 trials
Missouri 2 trials

Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.

What to do with this Sleep Deprivation page

35 registered trials, 19 currently recruiting, is a starting point for a conversation, not a diagnosis or a recommendation.

Trial and recruiting counts reflect ClinicalTrials.gov registry status as of the data vintage above; individual trial eligibility and enrollment status can change.

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This Sleep Deprivation condition card totals 35 registered trials; most-linked intervention Sleep Restriction; top US site state Massachusetts. See our editorial standards & corrections policy, the methodology behind these numbers, the data changelog, or report a data error.