Medical Information Only. Always consult your healthcare provider before enrolling in any clinical trial.
NCT01794689 · ClinicalTrials.gov registry record · NA
Mechanisms of Sleep Disruption Hyperalgesia
A NA study of Pain and Sleep Deprivation, sponsored by Johns Hopkins University.
- Completed
- Registry status
- NA
- Development phase
- 100
- Enrollment target
- 1
- Study location
NCT01794689: Completed NA study of Pain and Sleep Deprivation, sponsored by Johns Hopkins University.
NCT01794689 is a NA study of Pain and Sleep Deprivation that has completed, run by Johns Hopkins University. The registered enrollment target is 100 participants, below the 304-participant average among 374 other Pain trials with a reported enrollment target (67% lower). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT01794689, a NA study of Pain and Sleep Deprivation, has completed, sponsored by Johns Hopkins University.
- COMPLETED
- Registry status
- NA
- Development phase
- 100 participants
- Enrollment target
- 1
- Study location
Study Summary
Twenty percent of Americans suffer from chronic pain. Sleep disturbance is similarly prevalent and among the most common and disabling neurobehavioral problems associated with chronic pain. This research is designed to evaluate the effects of disrupted sleep patterns on mood, inflammation, the perception of pain, and pain relief. This study will help researchers understand the relationship between sleep and pain, and how sleep disturbance might influence chronic pain conditions.
Primary Outcome
The area of secondary hyperalgesia (2HA) to mechanical stimulation was quantified by stimulating along eight linear paths near the capsaicin treated site using a 15 gram nonpainful von Frey filament. Stimulation occurred until the participant reported a change in sensation from which a border was marked on the skin. The degree of 2HA was assessed by measuring the total surface area (mm\^2) of the marked borders. Data were collapsed by group to analyze the effects of FA vs US, irrespective of ran
Conditions Studied
Interventions
- DRUG Saline Placebo
- DRUG Morphine
- BEHAVIORAL Forced Awakenings
- BEHAVIORAL Uninterrupted Sleep
Study Locations (1)
Maryland
- Johns Hopkins University Bayview Medical Center - Baltimore
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 100 participants |
| Start Date | 2013-05 |
| Est. Completion | 2019-03-12 |
| Phase | NA |
What the finished NCT01794689 record still lists
NCT01794689 is an interventional study that assigns participants to a tested intervention. The registered 100 participants enrollment target is mid-sized for trials with a published cap, below the 304-participant average among 374 other Pain trials with a reported enrollment target (67% lower).
The record links to 2 conditions, with Pain appearing as the primary indexed condition, and to 4 interventions - of which Saline Placebo is the first listed.
NCT01794689 reports a single indexed study location in Maryland.
Frequently Asked Questions
What is clinical trial NCT01794689 about?
NCT01794689 is a clinical study titled "Mechanisms of Sleep Disruption Hyperalgesia". Twenty percent of Americans suffer from chronic pain. Sleep disturbance is similarly prevalent and among the most common and disabling neurobehavioral problems associated with chronic pain. This research is designed to evaluate the effects of disrupted sleep patterns on mood, inflammation, the perce...
What is the current status of trial NCT01794689?
This trial is currently completed. It is a NA study. The enrollment target is 100 participants. The study started on 2013-05. Estimated completion is 2019-03-12.
What conditions does trial NCT01794689 study?
This clinical trial studies the following conditions: Pain, Sleep Deprivation.
What interventions are being tested in trial NCT01794689?
The interventions under investigation include: Saline Placebo (DRUG), Morphine (DRUG), Forced Awakenings (BEHAVIORAL), Uninterrupted Sleep (BEHAVIORAL).
Who is sponsoring clinical trial NCT01794689?
This trial is sponsored by Johns Hopkins University, which has 1,448 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT01794689 being conducted?
This trial has 1 study location across Maryland. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
Similar trials for Pain
Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.
Where NCT01794689's enrollment target sits among peer trials
100 164th of 374 higher than 201 of 374 other Pain trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Pain trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
-
Postoperative Pain After Activation of Irrigant
RECRUITING · NA
-
Neural Mechanisms of Immersive Virtual Reality in Chronic Pain (VR TMD EEG)
RECRUITING · NA
-
Pain With Dementia
RECRUITING · NA
-
Oklahoma Study of Native American Pain Risk IV: Smoking Cessation and Pain
RECRUITING · NA
-
Peer Support for Adolescents and Emerging Adults With Sickle Cell Pain
RECRUITING · NA
-
TENS Analgesia During Outpatient Urethral Bulking for Stress Urinary Incontinence.
RECRUITING · NA
Nationwide trials with similar profiles
Cross-condition peers matched on enrollment target and registry start date, not the same-condition list above.
Similar enrollment target
- NCT01048281 · 100 participants
Clinical & Pathological Studies of Upper Gastrointestinal Carcinoma
- NCT01161199 · 100 participants
The Use of Leukapheresis to Support HIV Pathogenesis Studies
- NCT01327690 · 100 participants · Early Phase 1
Mental Health in Veterans and Families After Group Therapies
- NCT01730781 · 100 participants
Imaging Cannabinoid Receptors Using Positron Emission Tomography (PET) Scanning
Similar registry start date
- NCT05988463 · started 2027-01-01 · Phase 1
Dose-Escalation Study of Artesunate Patients With IPF
- NCT07219706 · started 2026-12-10 · NA
Dietary Fiber and Time Restricted Eating
- NCT02831335 · started 2026-12-01
Technical Development of Multi-Parametric Renocerebral MRI
- NCT05962346 · started 2026-12 · NA
Fetal Endoscopic Tracheal Occlusion for Congenital Diaphragmatic Hernia