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NCT04955431 · ClinicalTrials.gov registry record · NA

Circadian Rhythm Disruption Effects on Smoke Inhalation

A NA study of Inflammation and Sleep Deprivation, sponsored by University of Montana.

Completed
Registry status
NA
Development phase
10
Enrollment target
1
Study location

NCT04955431 is a NA study of Inflammation and Sleep Deprivation that has completed, run by University of Montana. The registered enrollment target is 10 participants, below the 288-participant average among 132 other Inflammation trials with a reported enrollment target (97% lower). The trial reports 1 study location across 1 state.

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The verdict

NCT04955431, a NA study of Inflammation and Sleep Deprivation, has completed, sponsored by University of Montana.

COMPLETED
Registry status
NA
Development phase
10 participants
Enrollment target
1
Study location

Study Summary

Particulate matter exposure during smoke inhalation provokes inflammatory immune responses in people exposed to burning biomass including fire fighters and civilians. Persistent occupational exposure to particulate matter represents a unique hazard for firefighters, underpinning a burgeoning research area. This trial will evaluate the effects of sleep deprivation and circadian rhythm disruption on the inflammatory response to woodsmoke associated particulate matter exposure. Participants will undergo 2 experimental trials in a randomized cross-over design. Participants will have either an 8-hour sleep opportunity or a 4-hour sleep opportunity prior to reporting to lab for a 45 minute simulated firefighting trial (wood smoke associated particulate matter filtered to 2.5 um at a concentration of 250 ug/m\^3, while exercising at a moderate intensity). The effects of sleep restriction and simulated firefighting will be measured.

Conditions Studied

Inflammation Sleep Deprivation Circadian Rhythm Sleep Disorder, Shift Work Type Smoke Inhalation

Interventions

  • BEHAVIORAL Sleep Restriction
  • BEHAVIORAL Normal Sleep

Study Locations (1)

Montana

  • School of Integrative Physiology and Athletic Training - Missoula

Trial Details

FieldValue
Enrollment Target 10 participants
Start Date 2022-01-24
Est. Completion 2022-04-17
Phase NA

Sponsor

University of Montana

24 total trials

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What the Registry Record Tells You About NCT04955431

The ClinicalTrials.gov registry entry for NCT04955431 describes a study currently listed as completed, categorized as NA. The registered enrollment target is 10 participants, a figure that helps gauge the scale of data the investigators plan to collect, below the 288-participant average among 132 other Inflammation trials with a reported enrollment target (97% lower). The listed sponsor is University of Montana, which has 24 total studies on file at ClinicalTrials.gov.

The record links to 4 conditions, with Inflammation appearing as the primary indexed condition, and to 2 interventions - of which Sleep Restriction is the first listed.

NCT04955431 reports 1 study location spanning 1 distinct geographic area - top geographies include Montana.

Frequently Asked Questions

What is clinical trial NCT04955431 about?

NCT04955431 is a clinical study titled "Circadian Rhythm Disruption Effects on Smoke Inhalation". Particulate matter exposure during smoke inhalation provokes inflammatory immune responses in people exposed to burning biomass including fire fighters and civilians. Persistent occupational exposure to particulate matter represents a unique hazard for firefighters, underpinning a burgeoning researc...

What is the current status of trial NCT04955431?

This trial is currently completed. It is a NA study. The enrollment target is 10 participants. The study started on 2022-01-24. Estimated completion is 2022-04-17.

What conditions does trial NCT04955431 study?

This clinical trial studies the following conditions: Inflammation, Sleep Deprivation, Circadian Rhythm Sleep Disorder, Shift Work Type, Smoke Inhalation.

What interventions are being tested in trial NCT04955431?

The interventions under investigation include: Sleep Restriction (BEHAVIORAL), Normal Sleep (BEHAVIORAL).

Who is sponsoring clinical trial NCT04955431?

This trial is sponsored by University of Montana, which has 24 total clinical trials registered on ClinicalTrials.gov.

Where is trial NCT04955431 being conducted?

This trial has 1 study location across Montana. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

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Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page mirrors this trial's own ClinicalTrials.gov registry record, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.