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NCT04535219 · ClinicalTrials.gov registry record · NA
Effect of Total Sleep Deprivation on Vascular Function
A NA study of Sleep Deprivation, sponsored by University of Florida.
- Completed
- Registry status
- NA
- Development phase
- 23
- Enrollment target
- 1
- Study location
NCT04535219: Completed NA study of Sleep Deprivation, sponsored by University of Florida.
NCT04535219 is a NA study of Sleep Deprivation that has completed, run by University of Florida. The registered enrollment target is 23 participants, below the 90-participant average among 34 other Sleep Deprivation trials with a reported enrollment target (74% lower). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT04535219, a NA study of Sleep Deprivation, has completed, sponsored by University of Florida.
- COMPLETED
- Registry status
- NA
- Development phase
- 23 participants
- Enrollment target
- 1
- Study location
Study Summary
Insufficient sleep is associated with an increased risk for cardiovascular disease. The causal mechanisms are currently unknown, but may include endothelial dysfunction. The purpose of this study is to examine the influence of sex and aging on the effects of total sleep deprivation on vascular function and whether exercise training attenuates these effects.
Primary Outcome
Endothelial function will be determined using brachial artery flow-mediated dilation via high resolution duplex ultrasonography. Reactive hyperemia will be produced by inflating a forearm cuff to \~250 mmHg for 5 minutes followed by rapid deflation.
Conditions Studied
Interventions
- OTHER Exercise
- OTHER Supervised Total Sleep Deprivation
Study Locations (1)
Florida
- University of Florida - Gainesville
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 23 participants |
| Start Date | 2021-07-11 |
| Est. Completion | 2022-08-02 |
| Phase | NA |
What the finished NCT04535219 record still lists
NCT04535219 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 23 participants, a relatively small participant target, below the 90-participant average among 34 other Sleep Deprivation trials with a reported enrollment target (74% lower).
The record links to 1 condition, with Sleep Deprivation appearing as the primary indexed condition, and to 2 interventions - of which Exercise is the first listed.
NCT04535219 reports a single indexed study location in Florida.
Frequently Asked Questions
What is clinical trial NCT04535219 about?
NCT04535219 is a clinical study titled "Effect of Total Sleep Deprivation on Vascular Function". Insufficient sleep is associated with an increased risk for cardiovascular disease. The causal mechanisms are currently unknown, but may include endothelial dysfunction. The purpose of this study is to examine the influence of sex and aging on the effects of total sleep deprivation on vascular funct...
What is the current status of trial NCT04535219?
This trial is currently completed. It is a NA study. The enrollment target is 23 participants. The study started on 2021-07-11. Estimated completion is 2022-08-02.
What conditions does trial NCT04535219 study?
This clinical trial studies the following conditions: Sleep Deprivation.
What interventions are being tested in trial NCT04535219?
The interventions under investigation include: Exercise (OTHER), Supervised Total Sleep Deprivation (OTHER).
Who is sponsoring clinical trial NCT04535219?
This trial is sponsored by University of Florida, which has 1,106 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT04535219 being conducted?
This trial has 1 study location across Florida. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
Similar trials for Sleep Deprivation
Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.
Where NCT04535219's enrollment target sits among peer trials
23 28th of 34 higher than 7 of 34 other Sleep Deprivation trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Sleep Deprivation trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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