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Shoulder Pain clinical trials
Every US clinical trial registered for Shoulder Pain — phase mix, recruiting status, and the sponsors running them, straight from the NIH ClinicalTrials.gov registry.
28 US clinical trials · 9 currently recruiting
The research picture
Shoulder Pain has 28 registered US clinical trials, 9 of them open to new participants right now — about 32% of the total.
- 9
- recruiting participants now
- 32%
- of trials open to enrollment
- 4
- in Phase 3–4 (later-stage)
- 3
- top sponsor: Texas Woman's University
Counts reflect the public ClinicalTrials.gov registry as last mirrored by PlainTrial. Status and phase are reported by each study's sponsor. This is reference information, not medical advice.
Active & Recent Trials
Zimmer Biomet Shoulder Arthroplasty PMCF
Zimmer Biomet
NCT04984291
Patient Outcomes Collection: How Can we do Better?
Rush University Medical Center
NCT03653455
Evaluating Hemidiaphragmatic Paralysis With Prolonged Neural Blockade From an Interscalene Brachial Plexus Block
Duke University
NCT04209504
Biopsychosocial Contributors to Irritability in Individuals With Shoulder Pain
University of Central Florida
NCT06429371
MDR - Comprehensive Primary Revision Stems PMCF
Zimmer Biomet
NCT06788717
The Effect of Micro Fragmented Adipose Tissue (MFAT) on Shoulder Osteoarthritis
Stanford University
NCT04929951
Embolization Treatment of Chronic Refractory Shoulder Tendinopathy
Brigham and Women's Hospital
NCT06095050
BFRT for Subacromial Pain
University of Florida
NCT06873113
Shoulder RFA Pilot Study
University of Utah
NCT06039345
Connective Tissue Matrix for Rotator Cuff Tendinopathy
Allegheny Singer Research Institute (also known as Allegheny Health Network Research Institute)
NCT06160427
Opioid-Free Pain Protocol After Shoulder Arthroplasty
Henry Ford Health System
NCT05488847
Natural History of Shoulder Pathology in Manual Wheelchair Users
The University of Texas Medical Branch, Galveston
NCT02600910
Dry Needling and Shoulder Muscle Blood Flow, Motions, and Pain Sensitivity in Individuals with Shoulder Pain
Texas Woman's University
NCT05596240
How Dry Needling at the Neck Affects Shoulder Movement, Strength, Pain, and Shoulder Circulation
Texas Woman's University
NCT06705634
Reliability and Validity of Patient Reported Outcome Measures in Head and Neck Cancer
Mayo Clinic
NCT02554968
A Randomized Controlled Trial of Best Approach to Care Compared to Diversified Chiropractic Adjustive Technique
Parker College of Chiropractic
NCT00163124
Maintenance of Shoulder Health and Function After Spinal Cord Injury
Rancho Research Institute
NCT02135978
Rotator Cuff Pathway
Hospital for Special Surgery, New York
NCT03717753
Peripheral Nerve Stimulation(PNS) for Subacromial Impingement Syndrome(SIS)
MetroHealth Medical Center
NCT03752619
Liposomal Bupivacaine vs Dexamethasone ISB
Hospital for Special Surgery, New York
NCT04047446
Liposomal Bupivacaine Plus Bupivacaine Peripheral Nerve Blockade Versus Ropivacaine Plus Dexamethasone Peripheral Nerve Blockade for Arthroscopic Rotator Cuff Repair
Hospital for Special Surgery Florida
NCT04737980
Dry Needling vs Dry Needling With ES in Patients With Neck/Shoulder Pain
Kindyle Brennan
NCT03638388
Dry Needling and Shoulder Muscle Blood Flow, Motions, and Pain Sensitivity
Texas Woman's University
NCT05467098
Subacromial Corticosteroid Injection for Hemiplegic Shoulder Pain
MetroHealth Medical Center
NCT00597766
A Pilot Study Comparing Two Rehabilitation Approaches for Individuals With Irritable Shoulder Pain
University of Central Florida
NCT06467123
Feasibility of Near-infrared Spectroscopy to Measure Cortical Pain Pathway (Brain) Activation During Dry Needling
Army-Baylor University Doctoral Program in Physical Therapy
NCT04170803
Microbreaks in the OR to Mitigate High Physical and Mental Demands
Mayo Clinic
NCT02565394
Platelet-Rich Plasma Therapy for Shoulder Pain in Persons With Spinal Cord Injury
Kessler Foundation
NCT01355549
Phase Distribution
| Phase | Trial count |
|---|---|
| Phase 1 | 3 |
| Phase 2 | 1 |
| Phase 4 | 4 |
Top Sponsors
Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.
Reading the Shoulder Pain Trial Landscape
ClinicalTrials.gov lists 28 US studies indexed under Shoulder Pain, and 9 of those are currently open to recruitment — roughly 32% of the total volume on the registry. That ratio is a useful proxy for activity level: a high share of recruiting studies often signals that research interest is current and that new enrollment opportunities are appearing, while a low share typically means the field is dominated by completed or follow-up work where most participant spots have already been filled. These counts reflect the public registry only and include studies at every stage of design, so they should be read as an index of research attention rather than as a measure of treatment availability.
The phase distribution for Shoulder Pain shows 4 late-stage studies (Phase 3 and Phase 4 combined) alongside 4 earlier-phase entries (Phase 1 through Phase 2). Phase 1 and Phase 2 studies focus on early safety signals, dosing, and preliminary effect, while Phase 3 studies are typically the larger efficacy and safety trials submitted toward regulatory review, and Phase 4 studies follow approved interventions in real-world use. A condition weighted toward later phases often reflects a mature research pipeline with several interventions already close to or past approval, whereas a heavier early-phase tilt suggests the field is still exploring new mechanisms and candidate approaches.
Top sponsor activity for Shoulder Pain is led by Texas Woman's University with 3 indexed trials, alongside 9 other organizations in the top contributor list. The list on this page surfaces up to 28 of the most relevant recent and active entries, ordered with recruiting studies first so practical options are visible. All figures are derived from the public ClinicalTrials.gov dataset maintained by the National Library of Medicine and are reproduced here for reference. Inclusion of a trial, sponsor, or intervention on this page is neither an endorsement nor a recommendation — eligibility, protocol changes, and site-level status can shift frequently, so always verify current details on ClinicalTrials.gov and consult a qualified healthcare provider before acting on anything you see here.
Frequently Asked Questions
How many clinical trials are there for Shoulder Pain?
PlainTrial tracks 28 US clinical trials for Shoulder Pain, of which 9 are currently recruiting participants. Data sourced from ClinicalTrials.gov.
How do I find a recruiting trial for Shoulder Pain?
Use the trial list above filtered by "Recruiting" status, or visit our trial finder at /recruiting to search by condition and state. Always discuss trial participation with your healthcare provider before enrolling.
Is this data current?
Data is sourced from ClinicalTrials.gov and reflects our most recent data pull. Trial status may have changed since then. Always verify current information at ClinicalTrials.gov before making decisions about participation.
Related
Disclaimer: This information is provided for informational purposes only and does not constitute professional advice. Data is sourced from ClinicalTrials.gov (National Library of Medicine). Consult a qualified professional before making decisions based on this data.
Read our methodology — how this data is sourced, computed, and verified.
Source: ClinicalTrials.gov (NIH/NLM) ClinicalTrials.gov AACT registry · 2026 Trial counts and statuses sourced from ClinicalTrials.gov. Sponsor counts include both industry and federal/academic sponsors.