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NCT01240876 · ClinicalTrials.gov registry record · Phase 1

Study to Evaluate the Safety and Efficacy of Placulumab (CEP-37247) Administered by the Transforaminal Epidural Route for the Treatment of Patients With Lumbosacral Radicular Pain Associated With Disk Herniation

A Phase 1 study of Sciatica, sponsored by Cephalon.

Completed
Registry status
Phase 1
Development phase
98
Enrollment target
20
Study locations

NCT01240876 is a Phase 1 study of Sciatica that has completed, run by Cephalon. The registered enrollment target is 98 participants, above the 71-participant average among 6 other Sciatica trials with a reported enrollment target (38% higher). The trial reports 20 study locations across 12 states.

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The verdict

NCT01240876, a Phase 1 study of Sciatica, has completed, sponsored by Cephalon.

COMPLETED
Registry status
Phase 1
Development phase
98 participants
Enrollment target
20
Study locations

Study Summary

The primary objective of the study is to evaluate the safety and efficacy of CEP-37247 compared with placebo as assessed by the occurrence of adverse events, and the mean change in average pain intensity (API) in the affected leg.

Conditions Studied

Interventions

  • DRUG Placebo
  • DRUG CEP-37247

Study Locations (20)

California

  • Teva Investigational Site 22 - La Mesa
  • Teva Investigational Site 18 - Laguna Hills
  • Teva Investigational Site 19 - Pasadena
  • Teva Investigational Site 2 - Pasadena

South Carolina

  • Teva Investigational Site 1 - Greenville
  • Teva Investigational Site 11 - North Charleston
  • Teva Investigational Site 6 - Spartanburg

Florida

  • Teva Investigational Site 14 - Orlando
  • Teva Investigational Site 5 - Sarasota

Georgia

  • Teva Investigational Site 10 - Marietta
  • Teva Investigational Site 13 - Marietta

Utah

  • Teva Investigational Site 4 - Orem
  • Teva Investigational Site 3 - Salt Lake City

Illinois

  • Teva Investigational Site 9 - Bloomington

Kansas

  • Teva Investigational Site 15 - Overland Park

Louisiana

  • Teva Investigational Site 8 - Shreveport

Trial Details

FieldValue
Enrollment Target 98 participants
Start Date 2011-01
Est. Completion 2013-04
Phase Phase 1

Sponsor

Cephalon

64 total trials

What the Registry Record Tells You About NCT01240876

The ClinicalTrials.gov registry entry for NCT01240876 describes a study currently listed as completed, categorized as Phase 1. The registered enrollment target is 98 participants, a figure that helps gauge the scale of data the investigators plan to collect, above the 71-participant average among 6 other Sciatica trials with a reported enrollment target (38% higher). The listed sponsor is Cephalon, which has 64 total studies on file at ClinicalTrials.gov.

The record links to 1 condition, with Sciatica appearing as the primary indexed condition, and to 2 interventions - of which Placebo is the first listed.

NCT01240876 reports 20 study locations spanning 12 distinct geographic areas - top geographies include California, South Carolina, Florida.

Frequently Asked Questions

What is clinical trial NCT01240876 about?

NCT01240876 is a clinical study titled "Study to Evaluate the Safety and Efficacy of Placulumab (CEP-37247) Administered by the Transforaminal Epidural Route for the Treatment of Patients With Lumbosacral Radicular Pain Associated With Disk Herniation". The primary objective of the study is to evaluate the safety and efficacy of CEP-37247 compared with placebo as assessed by the occurrence of adverse events, and the mean change in average pain intensity (API) in the affected leg.

What is the current status of trial NCT01240876?

This trial is currently completed. It is a Phase 1 study. The enrollment target is 98 participants. The study started on 2011-01. Estimated completion is 2013-04.

What conditions does trial NCT01240876 study?

This clinical trial studies the following conditions: Sciatica.

What interventions are being tested in trial NCT01240876?

The interventions under investigation include: Placebo (DRUG), CEP-37247 (DRUG).

Who is sponsoring clinical trial NCT01240876?

This trial is sponsored by Cephalon, which has 64 total clinical trials registered on ClinicalTrials.gov.

Where is trial NCT01240876 being conducted?

This trial has 20 study locations across California, Florida, Georgia, Illinois, Kansas. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

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Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page mirrors this trial's own ClinicalTrials.gov registry record, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.