Medical Information Only. Consult your healthcare provider before considering clinical trial enrollment.
Scar: early-phase trial registry
5 of 16 indexed Scar trials are currently recruiting, with more weight in Phase 1-2.
Corpus placement: #1,060 of 28,707 conditions by registered trial count.
16 US clinical trials · 5 currently recruiting · #1,060 of 28,707 conditions by registered trial count
Scar: 16 US clinical trials tracked, 5 recruiting.
Scar is the subject of 16 registered US clinical trials on ClinicalTrials.gov, 5 of them currently open to new participants. 0 are in Phase 3-4 (later-stage) and 4 in Phase 1-2 (earlier-stage). The most active sponsor is Melissa Pugliano-Mauro, running 2 of these trials.
Enrollment posture brief
Registry condition scar
OPEN 5 | RECR 31% | LATE 0 | EARLY 4 | RANK #1060 | SPON 2
Volume-matched condition peers
Nearest open-share peer: Aortic Valve Disease (31% recruiting · 16 trials)
Scar lists 5 open slots (31% of 16 indexed trials). Peers are matched on registered volume, not therapeutic-area browse lists. How peer matching works →
Key findings
What ClinicalTrials.gov does not surface for Scar on its own pages , computed from the registry mirror as of 2026-08-08. Each line carries its own denominator so it can be quoted as it stands.
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Scar is recruiting below its size-band peers.
5 of 16 indexed trials (31.3%) are open to enrollment, against a 46.5% average across 27,806 conditions with fewer than 20 trials. The peer set uses the same ClinicalTrials.gov-derived counts as this page.
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Sponsorship of Scar trials is spread across many organizations.
Melissa Pugliano-Mauro accounts for 2 of 16 trials (12.5%). 12 distinct sponsors appear on at least one study for this condition label.
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Most Scar trials plan to enrol fewer than 100 people.
Median target enrolment is 30 among the 16 trials that report a genuine target (sentinel values excluded). 15 of those (93.8%) plan for fewer than 100 participants.
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Scar research is mostly interventional.
16 interventional and 0 observational studies make up this index (100% interventional). Study type is sponsor-reported on ClinicalTrials.gov.
Open and recent trials
16 total, page 1 of 1
Impact of Suture Type on Pigment Disturbances in Patients of Skin of Color
Melissa Pugliano-Mauro
NCT05408117
Microneedling vs Dermabrasion for Early Facial Scar Resurfacing
Wake Forest University Health Sciences
NCT06171386
Zinc Oxide Versus Petrolatum Following Skin Surgery
Melissa Pugliano-Mauro
NCT03561376
Paraffin Wax and Exercise Prospective
Medstar Health Research Institute
NCT06786884
Dose Regimen Study of SLI-F06 in Healthy Volunteers
Scarless Laboratories
NCT05501327
PDL and Fractional Photothermolysis for Postsurgical Scars
Northwestern University
NCT03057964
Influence of Sun Protection and Linear Repair of Cutaneous Surgical Defects
University of California, Davis
NCT05074238
CO2 Laser Revision for Burn Related Donor Site Scars
Medstar Health Research Institute
NCT04456127
Randomized Controlled Trial Examining the Efficacy of Botulinum Toxin in Biopsy Scar Minimization
Henry Ford Health System
NCT05478551
A Study of Granexin® Gel for the Reduction of Scar Formation in Surgical Wounds Following Bilateral Anchor Incision Breast Surgery
Xequel Bio
NCT04331080
"A Clinical Study Investigating the Effectiveness of OTC Scar-management Modalities"
The Center for Clinical and Cosmetic Research
NCT04169490
A Comparison of Scar Infiltration, Scar Deactivation, and Standard of Care for the Treatment of Chronic, Post-Surgical Pain After Cesarean Section
Jennifer Loomis
NCT03936309
Aesthetic Outcome of Running Cuticular Suture Distance (2mm vs 5mm)
University of California, Davis
NCT04870008
Treatment of Surgical Scars Using the Pulsed Dye Laser
University of California, San Diego
NCT00970671
Pilot Study Investigating a Restorative Wound Care Cream Together With Petrolatum on Surgical Excisions
The Center for Clinical and Cosmetic Research
NCT04169438
Evaluation of Non-Ablative Laser for Treatment of Direct Brow Lift Scars
University of Miami
NCT02032641
Phase Distribution
| Phase | Trial count |
|---|---|
| Phase 1 | 1 |
| Phase 2 | 3 |
Top Sponsors
Named interventions
Most-linked intervention names on Scar records (sponsor-reported on ClinicalTrials.gov). Counts are trial links, not unique products.
US sites by state
Facility locations filed on Scar trials. A trial with sites in several states counts in each.
Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.
Related
What to do with this Scar page
16 registered trials, 5 currently recruiting, is a starting point for a conversation, not a diagnosis or a recommendation.
- 5 Scar trials are currently recruiting, check eligibility criteria before contacting a site. Browse recruiting trials
- Melissa Pugliano-Mauro sponsors the most Scar trials on record, review their full trial history before evaluating a specific study. See Melissa Pugliano-Mauro's trials
- Bring the specific trial ID (NCT number) to your own doctor before enrolling, this page is a directory, not medical guidance. Read the trial-finding guide
Trial and recruiting counts reflect ClinicalTrials.gov registry status as of the data vintage above; individual trial eligibility and enrollment status can change.
Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This Scar condition card totals 16 registered trials; most-linked intervention Active Comparator Silicone Gel (Kelo-Cote) + FS2 Emulsion Moisturizer; top US site state California. See our editorial standards & corrections policy, the methodology behind these numbers, the data changelog, or report a data error.