Medical Information Only. Consult your healthcare provider before considering clinical trial enrollment.
Scar clinical trials
Every US clinical trial registered for Scar — phase mix, recruiting status, and the sponsors running them, straight from the NIH ClinicalTrials.gov registry.
16 US clinical trials · 5 currently recruiting
The research picture
Scar has 16 registered US clinical trials, 5 of them open to new participants right now — about 31% of the total.
- 5
- recruiting participants now
- 31%
- of trials open to enrollment
- 0
- in Phase 3–4 (later-stage)
- 2
- top sponsor: Melissa Pugliano-Mauro
Counts reflect the public ClinicalTrials.gov registry as last mirrored by PlainTrial. Status and phase are reported by each study's sponsor. This is reference information, not medical advice.
Active & Recent Trials
Impact of Suture Type on Pigment Disturbances in Patients of Skin of Color
Melissa Pugliano-Mauro
NCT05408117
Microneedling vs Dermabrasion for Early Facial Scar Resurfacing
Wake Forest University Health Sciences
NCT06171386
Zinc Oxide Versus Petrolatum Following Skin Surgery
Melissa Pugliano-Mauro
NCT03561376
Paraffin Wax and Exercise Prospective
Medstar Health Research Institute
NCT06786884
Dose Regimen Study of SLI-F06 in Healthy Volunteers
Scarless Laboratories
NCT05501327
PDL and Fractional Photothermolysis for Postsurgical Scars
Northwestern University
NCT03057964
Influence of Sun Protection and Linear Repair of Cutaneous Surgical Defects
University of California, Davis
NCT05074238
CO2 Laser Revision for Burn Related Donor Site Scars
Medstar Health Research Institute
NCT04456127
Randomized Controlled Trial Examining the Efficacy of Botulinum Toxin in Biopsy Scar Minimization
Henry Ford Health System
NCT05478551
A Study of Granexin® Gel for the Reduction of Scar Formation in Surgical Wounds Following Bilateral Anchor Incision Breast Surgery
Xequel Bio
NCT04331080
"A Clinical Study Investigating the Effectiveness of OTC Scar-management Modalities"
The Center for Clinical and Cosmetic Research
NCT04169490
A Comparison of Scar Infiltration, Scar Deactivation, and Standard of Care for the Treatment of Chronic, Post-Surgical Pain After Cesarean Section
Jennifer Loomis
NCT03936309
Aesthetic Outcome of Running Cuticular Suture Distance (2mm vs 5mm)
University of California, Davis
NCT04870008
Treatment of Surgical Scars Using the Pulsed Dye Laser
University of California, San Diego
NCT00970671
Pilot Study Investigating a Restorative Wound Care Cream Together With Petrolatum on Surgical Excisions
The Center for Clinical and Cosmetic Research
NCT04169438
Evaluation of Non-Ablative Laser for Treatment of Direct Brow Lift Scars
University of Miami
NCT02032641
Phase Distribution
| Phase | Trial count |
|---|---|
| Phase 1 | 1 |
| Phase 2 | 3 |
Top Sponsors
Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.
Reading the Scar Trial Landscape
ClinicalTrials.gov lists 16 US studies indexed under Scar, and 5 of those are currently open to recruitment — roughly 31% of the total volume on the registry. That ratio is a useful proxy for activity level: a high share of recruiting studies often signals that research interest is current and that new enrollment opportunities are appearing, while a low share typically means the field is dominated by completed or follow-up work where most participant spots have already been filled. These counts reflect the public registry only and include studies at every stage of design, so they should be read as an index of research attention rather than as a measure of treatment availability.
The phase distribution for Scar shows 0 late-stage studies (Phase 3 and Phase 4 combined) alongside 4 earlier-phase entries (Phase 1 through Phase 2). Phase 1 and Phase 2 studies focus on early safety signals, dosing, and preliminary effect, while Phase 3 studies are typically the larger efficacy and safety trials submitted toward regulatory review, and Phase 4 studies follow approved interventions in real-world use. A condition weighted toward later phases often reflects a mature research pipeline with several interventions already close to or past approval, whereas a heavier early-phase tilt suggests the field is still exploring new mechanisms and candidate approaches.
Top sponsor activity for Scar is led by Melissa Pugliano-Mauro with 2 indexed trials, alongside 9 other organizations in the top contributor list. The list on this page surfaces up to 16 of the most relevant recent and active entries, ordered with recruiting studies first so practical options are visible. All figures are derived from the public ClinicalTrials.gov dataset maintained by the National Library of Medicine and are reproduced here for reference. Inclusion of a trial, sponsor, or intervention on this page is neither an endorsement nor a recommendation — eligibility, protocol changes, and site-level status can shift frequently, so always verify current details on ClinicalTrials.gov and consult a qualified healthcare provider before acting on anything you see here.
Frequently Asked Questions
How many clinical trials are there for Scar?
PlainTrial tracks 16 US clinical trials for Scar, of which 5 are currently recruiting participants. Data sourced from ClinicalTrials.gov.
How do I find a recruiting trial for Scar?
Use the trial list above filtered by "Recruiting" status, or visit our trial finder at /recruiting to search by condition and state. Always discuss trial participation with your healthcare provider before enrolling.
Is this data current?
Data is sourced from ClinicalTrials.gov and reflects our most recent data pull. Trial status may have changed since then. Always verify current information at ClinicalTrials.gov before making decisions about participation.
Related
Disclaimer: This information is provided for informational purposes only and does not constitute professional advice. Data is sourced from ClinicalTrials.gov (National Library of Medicine). Consult a qualified professional before making decisions based on this data.
Read our methodology — how this data is sourced, computed, and verified.
Source: ClinicalTrials.gov (NIH/NLM) ClinicalTrials.gov AACT registry · 2026 Trial counts and statuses sourced from ClinicalTrials.gov. Sponsor counts include both industry and federal/academic sponsors.