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ClinicalTrials.gov 5 recruiting now official registry

Scar clinical trials

Every US clinical trial registered for Scar — phase mix, recruiting status, and the sponsors running them, straight from the NIH ClinicalTrials.gov registry.

16 US clinical trials · 5 currently recruiting

The research picture

Scar has 16 registered US clinical trials, 5 of them open to new participants right now — about 31% of the total.

5
recruiting participants now
31%
of trials open to enrollment
0
in Phase 3–4 (later-stage)
2
top sponsor: Melissa Pugliano-Mauro

Counts reflect the public ClinicalTrials.gov registry as last mirrored by PlainTrial. Status and phase are reported by each study's sponsor. This is reference information, not medical advice.

Active & Recent Trials

RECRUITING NA 34 participants

Impact of Suture Type on Pigment Disturbances in Patients of Skin of Color

Melissa Pugliano-Mauro

NCT05408117

RECRUITING NA 30 participants

Microneedling vs Dermabrasion for Early Facial Scar Resurfacing

Wake Forest University Health Sciences

NCT06171386

RECRUITING Early Phase 1 30 participants

Zinc Oxide Versus Petrolatum Following Skin Surgery

Melissa Pugliano-Mauro

NCT03561376

RECRUITING NA 30 participants

Paraffin Wax and Exercise Prospective

Medstar Health Research Institute

NCT06786884

RECRUITING Phase 2 30 participants

Dose Regimen Study of SLI-F06 in Healthy Volunteers

Scarless Laboratories

NCT05501327

ACTIVE NOT RECRUITING NA 76 participants

PDL and Fractional Photothermolysis for Postsurgical Scars

Northwestern University

NCT03057964

ACTIVE NOT RECRUITING NA 50 participants

Influence of Sun Protection and Linear Repair of Cutaneous Surgical Defects

University of California, Davis

NCT05074238

ACTIVE NOT RECRUITING NA 25 participants

CO2 Laser Revision for Burn Related Donor Site Scars

Medstar Health Research Institute

NCT04456127

ACTIVE NOT RECRUITING Phase 2 12 participants

Randomized Controlled Trial Examining the Efficacy of Botulinum Toxin in Biopsy Scar Minimization

Henry Ford Health System

NCT05478551

COMPLETED Phase 2 184 participants

A Study of Granexin® Gel for the Reduction of Scar Formation in Surgical Wounds Following Bilateral Anchor Incision Breast Surgery

Xequel Bio

NCT04331080

COMPLETED NA 75 participants

"A Clinical Study Investigating the Effectiveness of OTC Scar-management Modalities"

The Center for Clinical and Cosmetic Research

NCT04169490

COMPLETED NA 60 participants

A Comparison of Scar Infiltration, Scar Deactivation, and Standard of Care for the Treatment of Chronic, Post-Surgical Pain After Cesarean Section

Jennifer Loomis

NCT03936309

COMPLETED NA 50 participants

Aesthetic Outcome of Running Cuticular Suture Distance (2mm vs 5mm)

University of California, Davis

NCT04870008

COMPLETED NA 28 participants

Treatment of Surgical Scars Using the Pulsed Dye Laser

University of California, San Diego

NCT00970671

COMPLETED NA 10 participants

Pilot Study Investigating a Restorative Wound Care Cream Together With Petrolatum on Surgical Excisions

The Center for Clinical and Cosmetic Research

NCT04169438

COMPLETED NA 9 participants

Evaluation of Non-Ablative Laser for Treatment of Direct Brow Lift Scars

University of Miami

NCT02032641

Phase Distribution

PhaseTrial count
Phase 1 1
Phase 2 3

Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.

Reading the Scar Trial Landscape

ClinicalTrials.gov lists 16 US studies indexed under Scar, and 5 of those are currently open to recruitment — roughly 31% of the total volume on the registry. That ratio is a useful proxy for activity level: a high share of recruiting studies often signals that research interest is current and that new enrollment opportunities are appearing, while a low share typically means the field is dominated by completed or follow-up work where most participant spots have already been filled. These counts reflect the public registry only and include studies at every stage of design, so they should be read as an index of research attention rather than as a measure of treatment availability.

The phase distribution for Scar shows 0 late-stage studies (Phase 3 and Phase 4 combined) alongside 4 earlier-phase entries (Phase 1 through Phase 2). Phase 1 and Phase 2 studies focus on early safety signals, dosing, and preliminary effect, while Phase 3 studies are typically the larger efficacy and safety trials submitted toward regulatory review, and Phase 4 studies follow approved interventions in real-world use. A condition weighted toward later phases often reflects a mature research pipeline with several interventions already close to or past approval, whereas a heavier early-phase tilt suggests the field is still exploring new mechanisms and candidate approaches.

Top sponsor activity for Scar is led by Melissa Pugliano-Mauro with 2 indexed trials, alongside 9 other organizations in the top contributor list. The list on this page surfaces up to 16 of the most relevant recent and active entries, ordered with recruiting studies first so practical options are visible. All figures are derived from the public ClinicalTrials.gov dataset maintained by the National Library of Medicine and are reproduced here for reference. Inclusion of a trial, sponsor, or intervention on this page is neither an endorsement nor a recommendation — eligibility, protocol changes, and site-level status can shift frequently, so always verify current details on ClinicalTrials.gov and consult a qualified healthcare provider before acting on anything you see here.

Frequently Asked Questions

How many clinical trials are there for Scar?

PlainTrial tracks 16 US clinical trials for Scar, of which 5 are currently recruiting participants. Data sourced from ClinicalTrials.gov.

How do I find a recruiting trial for Scar?

Use the trial list above filtered by "Recruiting" status, or visit our trial finder at /recruiting to search by condition and state. Always discuss trial participation with your healthcare provider before enrolling.

Is this data current?

Data is sourced from ClinicalTrials.gov and reflects our most recent data pull. Trial status may have changed since then. Always verify current information at ClinicalTrials.gov before making decisions about participation.

Related

Disclaimer: This information is provided for informational purposes only and does not constitute professional advice. Data is sourced from ClinicalTrials.gov (National Library of Medicine). Consult a qualified professional before making decisions based on this data.

Source: ClinicalTrials.gov (NIH/NLM) ClinicalTrials.gov AACT registry · 2026 Trial counts and statuses sourced from ClinicalTrials.gov. Sponsor counts include both industry and federal/academic sponsors.

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