Medical Information Only. Always consult your healthcare provider before enrolling in any clinical trial.
NCT05408117 · ClinicalTrials.gov registry record · NA
Impact of Suture Type on Pigment Disturbances in Patients of Skin of Color
A NA study of Scar, sponsored by Melissa Pugliano-Mauro.
- Recruiting
- Registry status
- NA
- Development phase
- 34
- Enrollment target
- 3
- Study locations
NCT05408117: Recruiting NA study of Scar, sponsored by Melissa Pugliano-Mauro.
NCT05408117 is a NA study of Scar that is actively recruiting participants, run by Melissa Pugliano-Mauro. The registered enrollment target is 34 participants, below the 47-participant average among 15 other Scar trials with a reported enrollment target (28% lower). The trial reports 3 study locations across 1 state. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT05408117, a NA study of Scar, is actively recruiting participants, sponsored by Melissa Pugliano-Mauro.
- RECRUITING
- Registry status
- NA
- Development phase
- 34 participants
- Enrollment target
- 3
- Study locations
Study Summary
The present study assesses if dissolvable (fast gut) or non-dissolvable (polypropylene) epidermal sutures produce better cosmetic results in terms of dyspigmentation and scarring in patients of skin of color. Through a split-wound study design, patients undergoing standard elliptical excisions at least 3 cm in length will receive each suture type. Measurements of dyspigmentation and scarring will be made at 7 days (for the head and neck), 10 days (for the trunk and extremities), and 3 months for all locations.
Primary Outcome
Patient and Observer Scar Assessment Scale (POSAS) outcome (6-60 scale). 6 subscales (which assess scar pain, itch, color, stiffness, thickness, and irregularity) comprise the POSAS measure and each are measured 1-10. Subscales will be summed to get a total score out of 60. Higher values represent worse outcomes.
Conditions Studied
Interventions
- DEVICE 5-0 Polypropylene epidermal suture
- DEVICE 5-0 Fast gut epidermal suture
Study Locations (3)
Pennsylvania
- UPMC Presbyterian - Pittsburgh
- UPMC St. Margaret - Pittsburgh
- UPMC Shadyside Place - Pittsburgh
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 34 participants |
| Start Date | 2022-10-01 |
| Est. Completion | 2026-10-01 |
| Phase | NA |
What NCT05408117 shows while recruiting
NCT05408117 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 34 participants, a relatively small participant target, below the 47-participant average among 15 other Scar trials with a reported enrollment target (28% lower).
The record links to 1 condition, with Scar appearing as the primary indexed condition, and to 2 interventions - of which 5-0 Polypropylene epidermal suture is the first listed.
NCT05408117 reports a single indexed study location in Pennsylvania.
Frequently Asked Questions
What is clinical trial NCT05408117 about?
NCT05408117 is a clinical study titled "Impact of Suture Type on Pigment Disturbances in Patients of Skin of Color". The present study assesses if dissolvable (fast gut) or non-dissolvable (polypropylene) epidermal sutures produce better cosmetic results in terms of dyspigmentation and scarring in patients of skin of color. Through a split-wound study design, patients undergoing standard elliptical excisions at le...
What is the current status of trial NCT05408117?
This trial is currently recruiting. It is a NA study. The enrollment target is 34 participants. The study started on 2022-10-01. Estimated completion is 2026-10-01.
What conditions does trial NCT05408117 study?
This clinical trial studies the following conditions: Scar.
What interventions are being tested in trial NCT05408117?
The interventions under investigation include: 5-0 Polypropylene epidermal suture (DEVICE), 5-0 Fast gut epidermal suture (DEVICE).
Who is sponsoring clinical trial NCT05408117?
This trial is sponsored by Melissa Pugliano-Mauro, which has 3 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT05408117 being conducted?
This trial has 3 study locations across Pennsylvania. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
Similar trials for Scar
Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.
Where NCT05408117's enrollment target sits among peer trials
34 7th of 15 higher than 9 of 15 other Scar trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Scar trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
-
Microneedling vs Dermabrasion for Early Facial Scar Resurfacing
RECRUITING · NA
-
Paraffin Wax and Exercise Prospective
RECRUITING · NA
-
CO2 Laser Revision for Burn Related Donor Site Scars
ACTIVE NOT RECRUITING · NA
-
Influence of Sun Protection and Linear Repair of Cutaneous Surgical Defects
ACTIVE NOT RECRUITING · NA
-
PDL and Fractional Photothermolysis for Postsurgical Scars
ACTIVE NOT RECRUITING · NA
-
Pilot Study Investigating a Restorative Wound Care Cream Together With Petrolatum on Surgical Excisions
COMPLETED · NA
Nationwide trials with similar profiles
Cross-condition peers matched on enrollment target and registry start date, not the same-condition list above.
Similar enrollment target
- NCT02897063 · 34 participants · Phase 1
Effects of Midodrine and Droxidopa on Splanchnic Capacitance in Autonomic Failure
- NCT03906617 · 34 participants · Phase 4
Bupivacaine/Epinephrine +Dexamethasone vs. Liposomal Bupivacaine
- NCT03992378 · 34 participants · NA
Neuromodulation to Regulate Inflammation and Autonomic Imbalance in Sepsis
- NCT04047849 · 34 participants · Phase 4
Latency Antibiotics in Previable PPROM, 18 0/7- 22 6/7 WGA
Similar registry start date
- NCT05962346 · started 2026-12 · NA
Fetal Endoscopic Tracheal Occlusion for Congenital Diaphragmatic Hernia
- NCT07125183 · started 2026-12 · Phase 2
Study on Efficacy and Tolerability of Weekly Doxorubicin in Elderly Patients With Advanced or Metastatic Leiomyosarcoma
- NCT07292298 · started 2026-11 · Phase 2
Phase 2 Single-Arm Rectal Cancer Brachytherapy for Patients With Low-Lying Residual Adenocarcinoma After Total Neoadjuvant Therapy to Improve Organ Preservation Rates
- NCT04263285 · started 2026-10 · NA
Treatment of Depression Post-SCI