Medical Information Only. Consult your healthcare provider before considering clinical trial enrollment.
Safety Issues clinical trials
Every US clinical trial registered for Safety Issues — phase mix, recruiting status, and the sponsors running them, straight from the NIH ClinicalTrials.gov registry.
14 US clinical trials · 2 currently recruiting
The research picture
Safety Issues has 14 registered US clinical trials, 2 of them open to new participants right now — about 14% of the total.
- 2
- recruiting participants now
- 14%
- of trials open to enrollment
- 0
- in Phase 3–4 (later-stage)
- 1
- top sponsor: International Partnership for Microbicides
Counts reflect the public ClinicalTrials.gov registry as last mirrored by PlainTrial. Status and phase are reported by each study's sponsor. This is reference information, not medical advice.
Active & Recent Trials
BeSMART Secure Storage Counseling in the Inpatient Setting
Vanderbilt University Medical Center
NCT06485141
Phase1/2a Study for IPG7236 in Patients With Advanced Solid Tumors
Nanjing Immunophage Biotech Co.
NCT05142592
Role of a CCK Receptor Antagonist Proglumide in Management of Chronic Pancreatitis
Georgetown University
NCT05551858
Directed Use of REmote Patient Management System AMia to Achieve Prescribed Dry Weight
University of California, San Diego
NCT04002440
A Phase 1 Study of the Safety and Tolerability of ICM20 in Adults
IC-MedTech Corporation
NCT05523596
Survey of Housestaff Attitudes Toward Patient Care and Safety
Weill Medical College of Cornell University
NCT00845052
Assessing the Effects of a Cannabidiol Derived From Hemp Supplement in Healthy Adults
University of South Carolina
NCT05212402
PK, Safety Study of 90-Day Use of Vaginal Rings Containing Dapivirine and Levonorgestrel
International Partnership for Microbicides
NCT05041699
Buck Institute Ketone Ester RCT
Buck Institute for Research on Aging
NCT05585762
A Phase 1 Study of EXT608 in Healthy Adults
Extend Biosciences
NCT05408663
Rectal Insert TAF/EVG Pre-Exposure Prophylaxis (RITE PrEP) Study
Eastern Virginia Medical School
NCT06274398
Oral Remimazolam With and Without Alcohol in Healthy Female Subjects
Paion UK
NCT04113343
Pupillary Unrest in Ambient Light, and Relationship to Opioid-Induced Respiratory Depression
University of California, San Francis
NCT04301895
Effect of Naringenin and Beta Carotene on Energy Expenditure
Pennington Biomedical Research Center
NCT04697355
Phase Distribution
| Phase | Trial count |
|---|---|
| Phase 1 | 8 |
Top Sponsors
Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.
Reading the Safety Issues Trial Landscape
ClinicalTrials.gov lists 14 US studies indexed under Safety Issues, and 2 of those are currently open to recruitment — roughly 14% of the total volume on the registry. That ratio is a useful proxy for activity level: a high share of recruiting studies often signals that research interest is current and that new enrollment opportunities are appearing, while a low share typically means the field is dominated by completed or follow-up work where most participant spots have already been filled. These counts reflect the public registry only and include studies at every stage of design, so they should be read as an index of research attention rather than as a measure of treatment availability.
The phase distribution for Safety Issues shows 0 late-stage studies (Phase 3 and Phase 4 combined) alongside 8 earlier-phase entries (Phase 1 through Phase 2). Phase 1 and Phase 2 studies focus on early safety signals, dosing, and preliminary effect, while Phase 3 studies are typically the larger efficacy and safety trials submitted toward regulatory review, and Phase 4 studies follow approved interventions in real-world use. A condition weighted toward later phases often reflects a mature research pipeline with several interventions already close to or past approval, whereas a heavier early-phase tilt suggests the field is still exploring new mechanisms and candidate approaches.
Top sponsor activity for Safety Issues is led by International Partnership for Microbicides with 1 indexed trial, alongside 9 other organizations in the top contributor list. The list on this page surfaces up to 14 of the most relevant recent and active entries, ordered with recruiting studies first so practical options are visible. All figures are derived from the public ClinicalTrials.gov dataset maintained by the National Library of Medicine and are reproduced here for reference. Inclusion of a trial, sponsor, or intervention on this page is neither an endorsement nor a recommendation — eligibility, protocol changes, and site-level status can shift frequently, so always verify current details on ClinicalTrials.gov and consult a qualified healthcare provider before acting on anything you see here.
Frequently Asked Questions
How many clinical trials are there for Safety Issues?
PlainTrial tracks 14 US clinical trials for Safety Issues, of which 2 are currently recruiting participants. Data sourced from ClinicalTrials.gov.
How do I find a recruiting trial for Safety Issues?
Use the trial list above filtered by "Recruiting" status, or visit our trial finder at /recruiting to search by condition and state. Always discuss trial participation with your healthcare provider before enrolling.
Is this data current?
Data is sourced from ClinicalTrials.gov and reflects our most recent data pull. Trial status may have changed since then. Always verify current information at ClinicalTrials.gov before making decisions about participation.
Related
Disclaimer: This information is provided for informational purposes only and does not constitute professional advice. Data is sourced from ClinicalTrials.gov (National Library of Medicine). Consult a qualified professional before making decisions based on this data.
Read our methodology — how this data is sourced, computed, and verified.
Source: ClinicalTrials.gov (NIH/NLM) ClinicalTrials.gov AACT registry · 2026 Trial counts and statuses sourced from ClinicalTrials.gov. Sponsor counts include both industry and federal/academic sponsors.