Medical Information Only. Consult your healthcare provider before considering clinical trial enrollment.
Safety Issues: early-phase trial registry
2 of 14 indexed Safety Issues trials are currently recruiting, with more weight in Phase 1-2.
Corpus placement: #1,230 of 28,707 conditions by registered trial count.
14 US clinical trials · 2 currently recruiting · #1,230 of 28,707 conditions by registered trial count
Safety Issues: 14 US clinical trials tracked, 2 recruiting.
Safety Issues is the subject of 14 registered US clinical trials on ClinicalTrials.gov, 2 of them currently open to new participants. 0 are in Phase 3-4 (later-stage) and 8 in Phase 1-2 (earlier-stage). The most active sponsor is International Partnership for Microbicides, running 1 of these trials.
Enrollment posture brief
Registry condition safety-issues
OPEN 2 | RECR 14% | LATE 0 | EARLY 8 | RANK #1230 | SPON 1
Volume-matched condition peers
Nearest open-share peer: Adverse Drug Events (14% recruiting · 7 trials)
Safety Issues lists 2 open slots (14% of 14 indexed trials). Peers are matched on registered volume, not therapeutic-area browse lists. How peer matching works →
Key findings
What ClinicalTrials.gov does not surface for Safety Issues on its own pages , computed from the registry mirror as of 2026-08-08. Each line carries its own denominator so it can be quoted as it stands.
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Safety Issues is recruiting below its size-band peers.
2 of 14 indexed trials (14.3%) are open to enrollment, against a 46.5% average across 27,806 conditions with fewer than 20 trials. The peer set uses the same ClinicalTrials.gov-derived counts as this page.
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Sponsorship of Safety Issues trials is spread across many organizations.
International Partnership for Microbicides accounts for 1 of 14 trials (7.1%). 14 distinct sponsors appear on at least one study for this condition label.
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Most Safety Issues trials plan to enrol fewer than 100 people.
Median target enrolment is 30 among the 14 trials that report a genuine target (sentinel values excluded). 11 of those (78.6%) plan for fewer than 100 participants.
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Safety Issues research is mostly interventional.
13 interventional and 1 observational studies make up this index (92.9% interventional). Study type is sponsor-reported on ClinicalTrials.gov.
Open and recent trials
14 total, page 1 of 1
BeSMART Secure Storage Counseling in the Inpatient Setting
Vanderbilt University Medical Center
NCT06485141
Phase1/2a Study for IPG7236 in Patients With Advanced Solid Tumors
Nanjing Immunophage Biotech Co.
NCT05142592
Role of a CCK Receptor Antagonist Proglumide in Management of Chronic Pancreatitis
Georgetown University
NCT05551858
Directed Use of REmote Patient Management System AMia to Achieve Prescribed Dry Weight
University of California, San Diego
NCT04002440
A Phase 1 Study of the Safety and Tolerability of ICM20 in Adults
IC-MedTech Corporation
NCT05523596
Survey of Housestaff Attitudes Toward Patient Care and Safety
Weill Medical College of Cornell University
NCT00845052
Assessing the Effects of a Cannabidiol Derived From Hemp Supplement in Healthy Adults
University of South Carolina
NCT05212402
PK, Safety Study of 90-Day Use of Vaginal Rings Containing Dapivirine and Levonorgestrel
International Partnership for Microbicides
NCT05041699
Buck Institute Ketone Ester RCT
Buck Institute for Research on Aging
NCT05585762
A Phase 1 Study of EXT608 in Healthy Adults
Extend Biosciences
NCT05408663
Rectal Insert TAF/EVG Pre-Exposure Prophylaxis (RITE PrEP) Study
Eastern Virginia Medical School
NCT06274398
Oral Remimazolam With and Without Alcohol in Healthy Female Subjects
Paion UK
NCT04113343
Pupillary Unrest in Ambient Light, and Relationship to Opioid-Induced Respiratory Depression
University of California, San Francisco
NCT04301895
Effect of Naringenin and Beta Carotene on Energy Expenditure
Pennington Biomedical Research Center
NCT04697355
Phase Distribution
| Phase | Trial count |
|---|---|
| Phase 1 | 8 |
Top Sponsors
Named interventions
Most-linked intervention names on Safety Issues records (sponsor-reported on ClinicalTrials.gov). Counts are trial links, not unique products.
US sites by state
Facility locations filed on Safety Issues trials. A trial with sites in several states counts in each.
Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.
Related
What to do with this Safety Issues page
14 registered trials, 2 currently recruiting, is a starting point for a conversation, not a diagnosis or a recommendation.
- 2 Safety Issues trials are currently recruiting, check eligibility criteria before contacting a site. Browse recruiting trials
- International Partnership for Microbicides sponsors the most Safety Issues trials on record, review their full trial history before evaluating a specific study. See International Partnership for Microbicides's trials
- Bring the specific trial ID (NCT number) to your own doctor before enrolling, this page is a directory, not medical guidance. Read the trial-finding guide
Trial and recruiting counts reflect ClinicalTrials.gov registry status as of the data vintage above; individual trial eligibility and enrollment status can change.
Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This Safety Issues condition card totals 14 registered trials; most-linked intervention Placebo; top US site state California. See our editorial standards & corrections policy, the methodology behind these numbers, the data changelog, or report a data error.