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NCT06274398 · ClinicalTrials.gov registry record · Phase 1
Rectal Insert TAF/EVG Pre-Exposure Prophylaxis (RITE PrEP) Study
A Phase 1 study of Safety Issues, sponsored by Eastern Virginia Medical School.
- Completed
- Registry status
- Phase 1
- Development phase
- 21
- Enrollment target
- 1
- Study location
NCT06274398 is a Phase 1 study of Safety Issues that has completed, run by Eastern Virginia Medical School. The registered enrollment target is 21 participants, below the 118-participant average among 13 other Safety Issues trials with a reported enrollment target (82% lower). The trial reports 1 study location across 1 state.
The verdict
NCT06274398, a Phase 1 study of Safety Issues, has completed, sponsored by Eastern Virginia Medical School.
- COMPLETED
- Registry status
- Phase 1
- Development phase
- 21 participants
- Enrollment target
- 1
- Study location
Study Summary
This is a double-blind, placebo-controlled, randomized two-phase study to evaluate the safety and pharmacokinetics (PK) of two TAF/EVG inserts administered rectally for 3 consecutive days, then every other day for 14 days.
Conditions Studied
Interventions
- DRUG TAF/EVG rectal insert
- DRUG Matching placebo rectal insert
Study Locations (1)
Georgia
- Emory Clinic - Atlanta
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 21 participants |
| Start Date | 2024-01-16 |
| Est. Completion | 2025-05-16 |
| Phase | Phase 1 |
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Full Details on ClinicalTrials.gov ↗What the Registry Record Tells You About NCT06274398
The ClinicalTrials.gov registry entry for NCT06274398 describes a study currently listed as completed, categorized as Phase 1. The registered enrollment target is 21 participants, a figure that helps gauge the scale of data the investigators plan to collect, below the 118-participant average among 13 other Safety Issues trials with a reported enrollment target (82% lower). The listed sponsor is Eastern Virginia Medical School, which has 36 total studies on file at ClinicalTrials.gov.
The record links to 1 condition, with Safety Issues appearing as the primary indexed condition, and to 2 interventions - of which TAF/EVG rectal insert is the first listed.
NCT06274398 reports 1 study location spanning 1 distinct geographic area - top geographies include Georgia.
Frequently Asked Questions
What is clinical trial NCT06274398 about?
NCT06274398 is a clinical study titled "Rectal Insert TAF/EVG Pre-Exposure Prophylaxis (RITE PrEP) Study". This is a double-blind, placebo-controlled, randomized two-phase study to evaluate the safety and pharmacokinetics (PK) of two TAF/EVG inserts administered rectally for 3 consecutive days, then every other day for 14 days.
What is the current status of trial NCT06274398?
This trial is currently completed. It is a Phase 1 study. The enrollment target is 21 participants. The study started on 2024-01-16. Estimated completion is 2025-05-16.
What conditions does trial NCT06274398 study?
This clinical trial studies the following conditions: Safety Issues.
What interventions are being tested in trial NCT06274398?
The interventions under investigation include: TAF/EVG rectal insert (DRUG), Matching placebo rectal insert (DRUG).
Who is sponsoring clinical trial NCT06274398?
This trial is sponsored by Eastern Virginia Medical School, which has 36 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT06274398 being conducted?
This trial has 1 study location across Georgia. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
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Read our methodology - how this data is sourced, computed, and verified.
Related
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