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NCT05041699 · ClinicalTrials.gov registry record · Phase 1

PK, Safety Study of 90-Day Use of Vaginal Rings Containing Dapivirine and Levonorgestrel

A Phase 1 study of Pharmacokinetics and Bleeding, sponsored by International Partnership for Microbicides.

Completed
Registry status
Phase 1
Development phase
40
Enrollment target
2
Study locations

NCT05041699 is a Phase 1 study of Pharmacokinetics and Bleeding that has completed, run by International Partnership for Microbicides. The registered enrollment target is 40 participants, below the 61-participant average among 37 other Pharmacokinetics trials with a reported enrollment target (34% lower). The trial reports 2 study locations across 2 states.

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The verdict

NCT05041699, a Phase 1 study of Pharmacokinetics and Bleeding, has completed, sponsored by International Partnership for Microbicides.

COMPLETED
Registry status
Phase 1
Development phase
40 participants
Enrollment target
2
Study locations

Study Summary

A double-blind, randomized trial (1:1) to characterize the local and systemic pharmacokinetics (PK) of two DPV-LNG vaginal ring formulations

Interventions

  • COMBINATION_PRODUCT IPM Ring-105
  • COMBINATION_PRODUCT IPM Ring-106

Study Locations (2)

Oregon

  • Oregon Health & Science University - Portland

Pennsylvania

  • UPMC Magee-Womens Hospital, Center for Family Planning Research - Pittsburgh

Trial Details

FieldValue
Enrollment Target 40 participants
Start Date 2022-06-20
Est. Completion 2024-10-07
Phase Phase 1

What the Registry Record Tells You About NCT05041699

The ClinicalTrials.gov registry entry for NCT05041699 describes a study currently listed as completed, categorized as Phase 1. The registered enrollment target is 40 participants, a figure that helps gauge the scale of data the investigators plan to collect, below the 61-participant average among 37 other Pharmacokinetics trials with a reported enrollment target (34% lower). The listed sponsor is International Partnership for Microbicides, which has 14 total studies on file at ClinicalTrials.gov.

The record links to 3 conditions, with Pharmacokinetics appearing as the primary indexed condition, and to 2 interventions - of which IPM Ring-105 is the first listed.

NCT05041699 reports 2 study locations spanning 2 distinct geographic areas - top geographies include Oregon, Pennsylvania.

Frequently Asked Questions

What is clinical trial NCT05041699 about?

NCT05041699 is a clinical study titled "PK, Safety Study of 90-Day Use of Vaginal Rings Containing Dapivirine and Levonorgestrel". A double-blind, randomized trial (1:1) to characterize the local and systemic pharmacokinetics (PK) of two DPV-LNG vaginal ring formulations

What is the current status of trial NCT05041699?

This trial is currently completed. It is a Phase 1 study. The enrollment target is 40 participants. The study started on 2022-06-20. Estimated completion is 2024-10-07.

What conditions does trial NCT05041699 study?

This clinical trial studies the following conditions: Pharmacokinetics, Bleeding, Safety Issues.

What interventions are being tested in trial NCT05041699?

The interventions under investigation include: IPM Ring-105 (COMBINATION_PRODUCT), IPM Ring-106 (COMBINATION_PRODUCT).

Who is sponsoring clinical trial NCT05041699?

This trial is sponsored by International Partnership for Microbicides, which has 14 total clinical trials registered on ClinicalTrials.gov.

Where is trial NCT05041699 being conducted?

This trial has 2 study locations across Oregon, Pennsylvania. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

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Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial

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