Medical Information Only. Consult your healthcare provider before considering clinical trial enrollment.
Retinopathy of Prematurity: full-pipeline trial registry
3 of 10 indexed Retinopathy of Prematurity trials are currently recruiting.
Corpus placement: #1,724 of 28,707 conditions by registered trial count.
10 US clinical trials · 3 currently recruiting · #1,724 of 28,707 conditions by registered trial count
Retinopathy of Prematurity: 10 US clinical trials tracked, 3 recruiting.
Retinopathy of Prematurity is the subject of 10 registered US clinical trials on ClinicalTrials.gov, 3 of them currently open to new participants. 1 are in Phase 3-4 (later-stage) and 1 in Phase 1-2 (earlier-stage). The most active sponsor is National Eye Institute (NEI), running 2 of these trials.
Enrollment posture brief
Registry condition retinopathy-of-prematurity
OPEN 3 | RECR 30% | LATE 1 | EARLY 1 | RANK #1724 | SPON 2
Volume-matched condition peers
Nearest open-share peer: Adrenocortical Carcinoma (30% recruiting · 10 trials)
Retinopathy of Prematurity lists 3 open slots (30% of 10 indexed trials). Peers are matched on registered volume, not therapeutic-area browse lists. How peer matching works →
Key findings
What ClinicalTrials.gov does not surface for Retinopathy of Prematurity on its own pages , computed from the registry mirror as of 2026-08-08. Each line carries its own denominator so it can be quoted as it stands.
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Retinopathy of Prematurity is recruiting below its size-band peers.
3 of 10 indexed trials (30%) are open to enrollment, against a 46.5% average across 27,806 conditions with fewer than 20 trials. The peer set uses the same ClinicalTrials.gov-derived counts as this page.
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One sponsor concentrates Retinopathy of Prematurity research.
National Eye Institute (NEI) accounts for 2 of 10 trials (20%). 8 distinct sponsors appear on at least one study for this condition label.
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Typical Retinopathy of Prematurity enrolment sits around 100 participants.
Median target enrolment is 100 among the 8 trials that report a genuine target (sentinel values excluded). 4 of those (50%) plan for fewer than 100 participants.
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Retinopathy of Prematurity splits between interventional and observational designs.
6 interventional and 4 observational studies make up this index (60% interventional). Study type is sponsor-reported on ClinicalTrials.gov.
Open and recent trials
10 total, page 1 of 1
Clinical and Genetic Analysis of ROP
Oregon Health and Science University
NCT04420156
Retinal Microanatomy in Retinopathy of Prematurity (BabySTEPS2)
Duke University
NCT04995341
Imaging Retinal Vasculature in Infant Eyes
Duke University
NCT05558059
Extension Study to Evaluate the Long-Term Outcomes of Pediatric Patients Who Received Treatment for Retinopathy of Prematurity in the VGFTe-ROP-1920 Study (Acronym: Butterfleye Next)
Regeneron Pharmaceuticals
NCT04515524
Bevacizumab Treatment For Type 1 ROP
Jaeb Center for Health Research
NCT04634578
Validation of i-ROP DL to Detect More Than Mild ROP
Siloam Vision
NCT06109285
Time Outside Target Oxygen Saturation Range in Preterm Infants and Long Term Outcomes and Preterm Infants
University of Virginia
NCT00845624
Skin and Serum Carotenoids in Preterm Infants Fed on a Formula Supplemented With Carotenoids
University of Utah
NCT00872664
The Effects of Light Reduction on Retinopathy of Prematurity (Light-ROP)
National Eye Institute (NEI)
NCT00000156
Cryotherapy for Retinopathy of Prematurity (CRYO-ROP) - Outcome Study of Cryotherapy for Retinopathy of Prematurity
National Eye Institute (NEI)
NCT00000133
Phase Distribution
| Phase | Trial count |
|---|---|
| Phase 2 | 1 |
| Phase 3 | 1 |
Top Sponsors
Named interventions
Most-linked intervention names on Retinopathy of Prematurity records (sponsor-reported on ClinicalTrials.gov). Counts are trial links, not unique products.
US sites by state
Facility locations filed on Retinopathy of Prematurity trials. A trial with sites in several states counts in each.
Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.
Related
What to do with this Retinopathy of Prematurity page
10 registered trials, 3 currently recruiting, is a starting point for a conversation, not a diagnosis or a recommendation.
- 3 Retinopathy of Prematurity trials are currently recruiting, check eligibility criteria before contacting a site. Browse recruiting trials
- National Eye Institute (NEI) sponsors the most Retinopathy of Prematurity trials on record, review their full trial history before evaluating a specific study. See National Eye Institute (NEI)'s trials
- Bring the specific trial ID (NCT number) to your own doctor before enrolling, this page is a directory, not medical guidance. Read the trial-finding guide
Trial and recruiting counts reflect ClinicalTrials.gov registry status as of the data vintage above; individual trial eligibility and enrollment status can change.
Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This Retinopathy of Prematurity condition card totals 10 registered trials; most-linked intervention Trans-scleral Cryotherapy; top US site state Pennsylvania. See our editorial standards & corrections policy, the methodology behind these numbers, the data changelog, or report a data error.