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ACTIVE NOT RECRUITING

A Real-World Study to Gain Clinical Insights Into Roche Ophthalmology Products

NCT05476926 · View on ClinicalTrials.gov ↗

Study Summary

The VOYAGER study is a primary data collection, non-interventional, prospective, multinational, multicenter study. It is designed to collect real-world, long-term data to explore long-term effectiveness, safety, clinical insights, treatment patterns, and factors driving the treatment decisions among patients being treated with specified Roche ophthalmology products in approved retinal indications (Faricimab for neovascular age-related macular degeneration \[nAMD\], diabetic macular edema \[DME\], and retinal vein occlusion; Port Delivery System with Ranibizumab for nAMD) in routine clinical practice. This study will not provide or make recommendations on use of any products including Roche products; treatment decisions will be determined by the treating physician and must be made independently to the decision to participate in this study. Participation in this study will not change or influence a patient's standard of care in any way.

Interventions

  • DRUG Faricimab
  • COMBINATION_PRODUCT Port Delivery System with Ranibizumab

Study Locations (20)

California

  • California Eye Specialists Medical group Inc. — Pasadena
  • Retinal Consultants Medical Group — Sacramento

Florida

  • Advanced Research — Coral Springs
  • Retina Specialty Institute — Pensacola

Illinois

  • University Retina and Macula Associates, PC — Lemont
  • Springfield Clinic, Llp — Springfield

Texas

  • Brown Retina Institute — San Antonio
  • Retina Center of Texas — Southlake

Virginia

  • Piedmont Eye Center — Lynchburg
  • Wagner Macula and Retina Center — Norfolk

Arizona

  • Retinal Research Institute, LLC — Phoenix

Kentucky

  • Retina Associates of Kentucky — Lexington

Maryland

  • Cumberland Valley Retina Consultants PC — Hagerstown

Trial Details

FieldValue
Enrollment Target 6,000 participants
Start Date 2022-11-21
Est. Completion 2027-11-30

Sponsor

Hoffmann-La Roche

758 total trials

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Full Details on ClinicalTrials.gov ↗

What the Registry Record Tells You About NCT05476926

The ClinicalTrials.gov registry entry for NCT05476926 describes a study currently listed as active not recruiting. It is categorized as an unspecified phase, which is the standard way researchers label where a study sits along the investigational pathway from early safety work through later efficacy and post-marketing evaluation. The registered enrollment target is 6,000 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is Hoffmann-La Roche, which has 758 total studies on file at ClinicalTrials.gov, and sponsors are the parties responsible for study design, oversight, and regulatory filings.

The record links to 6 conditions, with Diabetic Macular Edema appearing as the primary indexed condition, and to 2 interventions — of which Faricimab is the first listed. Interventions can include drugs, devices, procedures, behavioral programs, or observational arms, and each is tracked as a separate registry field so that downstream queries can filter accurately. When a trial lists multiple interventions, it usually reflects a multi-arm design or a comparison protocol rather than a single treatment being tested in isolation. The brief summary published in the registry is the clearest source of protocol intent and should be read before drawing conclusions from any sidebar tags.

Geographic footprint matters for practical reasons: NCT05476926 reports 20 study locations spanning 15 distinct geographic areas — top geographies include California, Florida, Illinois. A larger site network tends to correlate with broader recruitment capacity, but it does not imply anything about study quality, and site-level enrollment status can diverge from the overall registry status shown above. Every data point on this page comes from the public ClinicalTrials.gov dataset and is reproduced here for reference only; it is not a medical recommendation, an endorsement of the sponsor, or an invitation to enroll. Verify current status, eligibility criteria, and contact details directly at ClinicalTrials.gov, and discuss any participation decision with your own healthcare provider.

Frequently Asked Questions

What is clinical trial NCT05476926 about?

NCT05476926 is a clinical study titled "A Real-World Study to Gain Clinical Insights Into Roche Ophthalmology Products". The VOYAGER study is a primary data collection, non-interventional, prospective, multinational, multicenter study. It is designed to collect real-world, long-term data to explore long-term effectiveness, safety, clinical insights, treatment patterns, and factors driving the treatment decisions among...

What is the current status of trial NCT05476926?

This trial is currently active not recruiting. The enrollment target is 6,000 participants. The study started on 2022-11-21. Estimated completion is 2027-11-30.

What conditions does trial NCT05476926 study?

This clinical trial studies the following conditions: Diabetic Macular Edema, Neovascular Age-related Macular Degeneration, Retinal Vein Occlusion, Branch Retinal Vein Occlusion, Central Retinal Vein Occlusion. These conditions were identified from the trial registry and reflect the primary focus areas of the research.

What interventions are being tested in trial NCT05476926?

The interventions under investigation include: Faricimab (DRUG), Port Delivery System with Ranibizumab (COMBINATION_PRODUCT). Each intervention is being evaluated for safety and efficacy as part of this clinical study.

Who is sponsoring clinical trial NCT05476926?

This trial is sponsored by Hoffmann-La Roche, which has 758 total clinical trials registered on ClinicalTrials.gov. The sponsor is responsible for the study's design, funding, and regulatory compliance.

Where is trial NCT05476926 being conducted?

This trial has 20 study locations across Arizona, California, Florida, Illinois, Kentucky. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

Related

Data sourced from official U.S. government datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial