Medical Information Only. Always consult your healthcare provider before enrolling in any clinical trial.

COMPLETED Phase 2

Safety and Proof of Concept Study of ANXV (Annexin A5) in Patients With Retinal Vein Occlusion

NCT05532735 · View on ClinicalTrials.gov ↗

Study Summary

Open-label, dose ascending safety, tolerability, and proof of concept study to evaluate the use of ANXV (human recombinant Annexin A5) in the treatment of subjects with recently diagnosed Retinal Vein Occlusion.

Conditions Studied

Interventions

  • BIOLOGICAL ANXV

Study Locations (7)

Texas

  • Retina Consultants of Texas — Bellaire
  • Valley Retina Institute — McAllen
  • Retina Consultants of Texas — San Antonio

Louisiana

  • Eye Associates of Northeast Louisiana — West Monroe

Maryland

  • Cumberland Valley Retina Consultants — Hagerstown

Oklahoma

  • Tulsa Retina Consultants — Tulsa

Virginia

  • Virginia Retina Center — Warrenton

Trial Details

FieldValue
Enrollment Target 16 participants
Start Date 2022-08-24
Est. Completion 2024-11-11
Phase Phase 2

Sponsor

Annexin Pharmaceuticals AB

1 total trials

Interested in This Trial?

Always speak with your doctor before enrolling in a clinical trial.

Full Details on ClinicalTrials.gov ↗

What the Registry Record Tells You About NCT05532735

The ClinicalTrials.gov registry entry for NCT05532735 describes a study currently listed as completed. It is categorized as Phase 2, which is the standard way researchers label where a study sits along the investigational pathway from early safety work through later efficacy and post-marketing evaluation. The registered enrollment target is 16 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is Annexin Pharmaceuticals AB, which has 1 total studies on file at ClinicalTrials.gov, and sponsors are the parties responsible for study design, oversight, and regulatory filings.

The record links to 1 condition, with Retinal Vein Occlusion appearing as the primary indexed condition, and to 1 intervention — of which ANXV is the first listed. Interventions can include drugs, devices, procedures, behavioral programs, or observational arms, and each is tracked as a separate registry field so that downstream queries can filter accurately. When a trial lists multiple interventions, it usually reflects a multi-arm design or a comparison protocol rather than a single treatment being tested in isolation. The brief summary published in the registry is the clearest source of protocol intent and should be read before drawing conclusions from any sidebar tags.

Geographic footprint matters for practical reasons: NCT05532735 reports 7 study locations spanning 5 distinct geographic areas — top geographies include Texas, Louisiana, Maryland. A larger site network tends to correlate with broader recruitment capacity, but it does not imply anything about study quality, and site-level enrollment status can diverge from the overall registry status shown above. Every data point on this page comes from the public ClinicalTrials.gov dataset and is reproduced here for reference only; it is not a medical recommendation, an endorsement of the sponsor, or an invitation to enroll. Verify current status, eligibility criteria, and contact details directly at ClinicalTrials.gov, and discuss any participation decision with your own healthcare provider.

Frequently Asked Questions

What is clinical trial NCT05532735 about?

NCT05532735 is a clinical study titled "Safety and Proof of Concept Study of ANXV (Annexin A5) in Patients With Retinal Vein Occlusion". Open-label, dose ascending safety, tolerability, and proof of concept study to evaluate the use of ANXV (human recombinant Annexin A5) in the treatment of subjects with recently diagnosed Retinal Vein Occlusion.

What is the current status of trial NCT05532735?

This trial is currently completed. It is a Phase 2 study. The enrollment target is 16 participants. The study started on 2022-08-24. Estimated completion is 2024-11-11.

What conditions does trial NCT05532735 study?

This clinical trial studies the following conditions: Retinal Vein Occlusion. These conditions were identified from the trial registry and reflect the primary focus areas of the research.

What interventions are being tested in trial NCT05532735?

The interventions under investigation include: ANXV (BIOLOGICAL). Each intervention is being evaluated for safety and efficacy as part of this clinical study.

Who is sponsoring clinical trial NCT05532735?

This trial is sponsored by Annexin Pharmaceuticals AB, which has 1 total clinical trials registered on ClinicalTrials.gov. The sponsor is responsible for the study's design, funding, and regulatory compliance.

Where is trial NCT05532735 being conducted?

This trial has 7 study locations across Louisiana, Maryland, Oklahoma, Texas, Virginia. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

Related

Data sourced from official U.S. government datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial