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NCT03016741 · ClinicalTrials.gov registry record · Phase 4
Cognitive Effects of Androgen Receptor Directed Therapies for Advanced Prostate Cancer
A Phase 4 study of Metastatic Prostate Carcinoma and Recurrent Prostate Carcinoma, sponsored by Northwestern University.
- Active
- Registry status
- Phase 4
- Development phase
- 100
- Enrollment target
- 5
- Study locations
NCT03016741 is a Phase 4 study of Metastatic Prostate Carcinoma and Recurrent Prostate Carcinoma that is active but no longer recruiting, run by Northwestern University. The registered enrollment target is 100 participants, below the 130-participant average among 37 other Metastatic Prostate Carcinoma trials with a reported enrollment target (23% lower). The trial reports 5 study locations across 5 states.
The verdict
NCT03016741, a Phase 4 study of Metastatic Prostate Carcinoma and Recurrent Prostate Carcinoma, is active but no longer recruiting, sponsored by Northwestern University.
- ACTIVE NOT RECRUITING
- Registry status
- Phase 4
- Development phase
- 100 participants
- Enrollment target
- 5
- Study locations
Study Summary
This clinical trial studies cognitive function in men with prostate cancer treated with androgen receptor directed therapies such as abiraterone acetate and enzalutamide. The investigators use MRI imaging (non-invasive, non-contrast) to see whether there are changes in brain structure or activity related to treatment that may be related to changes in cognitive function. The investigators are also looking for genetic variations that might make patients more or less sensitive to cognitive changes during treatment for prostate cancer.
Conditions Studied
Interventions
- DRUG Prednisone
- DRUG Enzalutamide
- DRUG Abiraterone Acetate
- BIOLOGICAL GnRH agonist/antagonist
Study Locations (5)
California
- City of Hope Comprehensive Cancer Center - Los Angeles
Illinois
- Northwestern University - Chicago
Louisiana
- Tulane Cancer Center - New Orleans
Minnesota
- University of Minnesota: Masonic Cancer Center - Minneapolis
Tennessee
- Vanderbilt-Ingram Cancer Center - Nashville
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 100 participants |
| Start Date | 2017-03-31 |
| Est. Completion | 2029-08 |
| Phase | Phase 4 |
Interested in This Trial?
Full Details on ClinicalTrials.gov ↗What the Registry Record Tells You About NCT03016741
The ClinicalTrials.gov registry entry for NCT03016741 describes a study currently listed as active not recruiting, categorized as Phase 4. The registered enrollment target is 100 participants, a figure that helps gauge the scale of data the investigators plan to collect, below the 130-participant average among 37 other Metastatic Prostate Carcinoma trials with a reported enrollment target (23% lower). The listed sponsor is Northwestern University, which has 1,209 total studies on file at ClinicalTrials.gov.
The record links to 5 conditions, with Metastatic Prostate Carcinoma appearing as the primary indexed condition, and to 4 interventions - of which Prednisone is the first listed.
NCT03016741 reports 5 study locations spanning 5 distinct geographic areas - top geographies include California, Illinois, Louisiana.
Frequently Asked Questions
What is clinical trial NCT03016741 about?
NCT03016741 is a clinical study titled "Cognitive Effects of Androgen Receptor Directed Therapies for Advanced Prostate Cancer". This clinical trial studies cognitive function in men with prostate cancer treated with androgen receptor directed therapies such as abiraterone acetate and enzalutamide. The investigators use MRI imaging (non-invasive, non-contrast) to see whether there are changes in brain structure or activity re...
What is the current status of trial NCT03016741?
This trial is currently active not recruiting. It is a Phase 4 study. The enrollment target is 100 participants. The study started on 2017-03-31. Estimated completion is 2029-08.
What conditions does trial NCT03016741 study?
This clinical trial studies the following conditions: Metastatic Prostate Carcinoma, Recurrent Prostate Carcinoma, Stage IV Prostate Cancer, Castration Resistant Prostatic Cancer, Hormone-refractory Prostate Cancer.
What interventions are being tested in trial NCT03016741?
The interventions under investigation include: Prednisone (DRUG), Enzalutamide (DRUG), Abiraterone Acetate (DRUG), GnRH agonist/antagonist (BIOLOGICAL).
Who is sponsoring clinical trial NCT03016741?
This trial is sponsored by Northwestern University, which has 1,209 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT03016741 being conducted?
This trial has 5 study locations across California, Illinois, Louisiana, Minnesota, Tennessee. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
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Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page mirrors this trial's own ClinicalTrials.gov registry record, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.