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ClinicalTrials.gov 12 recruiting now early-phase tilt

Psychological Distress: early-phase trial registry

12 of 29 indexed Psychological Distress trials are currently recruiting, with more weight in Phase 1-2.

Corpus placement: #552 of 28,707 conditions by registered trial count.

29 US clinical trials · 12 currently recruiting · #552 of 28,707 conditions by registered trial count

Psychological Distress: 29 US clinical trials tracked, 12 recruiting.

Psychological Distress is the subject of 29 registered US clinical trials on ClinicalTrials.gov, 12 of them currently open to new participants. 1 are in Phase 3-4 (later-stage) and 4 in Phase 1-2 (earlier-stage). The most active sponsor is San Diego State University, running 2 of these trials.

Enrollment posture brief

Registry condition psychological-distress

OPEN 12 | RECR 41% | LATE 1 | EARLY 4 | RANK #552 | SPON 2

Nearest open-share peer: Dyslipidemias (41% recruiting · 29 trials)

Advanced Breast Cancer62.1%Amyloidosis51.7%Psychological Distress (this)41%Arthritis, Rheumatoid17.2%Adult Acute Myeloid Leukemia0%
Open-enrollment share among volume-matched conditions near Psychological Distress

Psychological Distress lists 12 open slots (41% of 29 indexed trials). Peers are matched on registered volume, not therapeutic-area browse lists. How peer matching works →

Key findings

What ClinicalTrials.gov does not surface for Psychological Distress on its own pages , computed from the registry mirror as of 2026-08-08. Each line carries its own denominator so it can be quoted as it stands.

  1. Psychological Distress recruits in line with its size-band peers.

    12 of 29 indexed trials (41.4%) are open to enrollment, against a 39.7% average across 762 conditions with 20-99 trials. The peer set uses the same ClinicalTrials.gov-derived counts as this page.

  2. Sponsorship of Psychological Distress trials is spread across many organizations.

    San Diego State University accounts for 2 of 29 trials (6.9%). 24 distinct sponsors appear on at least one study for this condition label.

  3. Most Psychological Distress trials plan to enrol fewer than 100 people.

    Median target enrolment is 73 among the 29 trials that report a genuine target (sentinel values excluded). 19 of those (65.5%) plan for fewer than 100 participants.

  4. Psychological Distress research is mostly interventional.

    28 interventional and 1 observational studies make up this index (96.6% interventional). Study type is sponsor-reported on ClinicalTrials.gov.

Phase 11Phase 23Phase 41

Open and recent trials

29 total, page 1 of 1

RECRUITING NA 1,000 participants

REstoring Mental Health Through COmmUnity-based Psychological Services in New York City

George Washington University

NCT04913766

RECRUITING Phase 2 452 participants

The Breast Cancer Survivors and Partners Online Research Together (SUPORT) Project

University of Arizona

NCT05676255

RECRUITING NA 400 participants

Latinos Understanding the Need for Adherence in Diabetes Using E-Health

San Diego State University

NCT05570734

RECRUITING Phase 2 192 participants

Meditation to Reduce Firefighter Distress

University of Arizona

NCT06518616

RECRUITING NA 90 participants

Study to Determine How Different Types of Coping Strategies Can Help People Manage Pain and Distress After Surgery

University of Utah

NCT06858202

RECRUITING NA 90 participants

PODER Familiar: Health Promotion for Latino Families of Children With IDD

University of Texas at Austin

NCT05713617

RECRUITING Phase 4 80 participants

Psychopharmacological Treatment of Emotional Distress

Icahn School of Medicine at Mount Sinai

NCT06133114

RECRUITING NA 80 participants

Development and Testing of imHere4U: A Digital Suicide Prevention Intervention for Cyberbullied Adolescents

University of Pittsburgh

NCT06002191

RECRUITING NA 60 participants

Mindfulness Training and Respiration Biosignal Feedback - Study 2

Equa Health

NCT07136948

RECRUITING NA 40 participants

Behavioral Intervention to Reduce Stress Among Black Gender Minority Women

Emory University

NCT05436106

RECRUITING 36 participants

CARE-BI:a Pilot Study to Improve Patient Comfort and Reduce Psychological Distress During IA Removal

M.D. Anderson Cancer Center

NCT07335302

RECRUITING NA 20 participants

A Dyadic Intervention for Young Adult Patients With Cancer and Their Partner Caregivers

Massachusetts General Hospital

NCT06172907

ACTIVE NOT RECRUITING NA 360 participants

Creating Access to Resources and Economic Support

Duke University

NCT05971160

ACTIVE NOT RECRUITING NA 220 participants

A Hybrid Effectiveness Implementation Study of Latino/a Alcohol and Drug Users

Boston University Charles River Campus

NCT04771650

ACTIVE NOT RECRUITING NA 50 participants

Pomegranate Supplementation and Well-Being Among Medical Students and Residents

University of Mississippi Medical Center

NCT03063372

ACTIVE NOT RECRUITING NA 50 participants

Effects of Grape Powder on Psychological Distress and Gut Microbiota in College Students

Rutgers, The State University of New Jersey

NCT07214428

ACTIVE NOT RECRUITING NA 40 participants

Rise & Renew: Supporting Well-Being in Black Women After the Loss of a Loved One

Lillian Haley, PhD

NCT07009795

ACTIVE NOT RECRUITING NA 40 participants

Bright IDEAS for Pediatric Palliative Care: A Problem-Solving Skills Intervention to Empower Parent Resilience

Children's Hospital Los Angeles

NCT05899998

ACTIVE NOT RECRUITING Phase 1 24 participants

Palliadelic Treatment to Reduce Psychological Distress in Persons With Advanced Gastrointestinal Cancers

University of Nebraska

NCT05220046

COMPLETED NA 8,194 participants

Basic Income Guaranteed: Los Angeles Economic Assistance Pilot

University of Pennsylvania

NCT07200648

COMPLETED NA 890 participants

Testing the Effectiveness of an Online Behavioral Intervention in Reducing Loneliness

Happify

NCT04112225

COMPLETED NA 456 participants

Latinos Understanding the Need for Adherence in Diabetes

San Diego State University

NCT03983499

COMPLETED NA 151 participants

A Needs-focused Palliative Care Intervention for Older Adults in ICUs

Duke University

NCT04414787

COMPLETED NA 73 participants

Three-Principles Approach for Incarcerated Adults

Pacific University

NCT04747704

COMPLETED NA 53 participants

Examine the Effects of Meditation on Daily Psychological Stress Responses in Woman With a History of Child Adversity

University of California, San Francisco

NCT04606199

COMPLETED Phase 2 38 participants

Diabetes Homeless Medication Support

Hennepin Healthcare Research Institute

NCT05258630

COMPLETED NA 26 participants

ASD (Autism Spectrum Disorder) Telehealth for Distress Related to COVID-19

Rutgers, The State University of New Jersey

NCT04460677

COMPLETED NA 11 participants

Development and Feasibility Testing of a Suicide Prevention Intervention for Sexual and Gender Minority Youth

University of Pittsburgh

NCT05724784

COMPLETED NA 10 participants

Mindful Movement and Breathing to Improve Outcomes of Gynecologic Surgery

Wake Forest University Health Sciences

NCT01593657

Phase Distribution

PhaseTrial count
Phase 1 1
Phase 2 3
Phase 4 1

Named interventions

Most-linked intervention names on Psychological Distress records (sponsor-reported on ClinicalTrials.gov). Counts are trial links, not unique products.

Flourish Behavioral
2 trials
Volumetric Incentive Spirometry Procedure
1 trials
The Observer Mobility Scale Procedure
1 trials
Mindful Movement and Breathing program Other
1 trials
Mindfulness-based intervention, up to 5 minutes 0-3 times/day Behavioral
1 trials
Special Intervention Behavioral
1 trials
Happify Behavioral
1 trials
Emotional Support Plan Behavioral
1 trials

US sites by state

Facility locations filed on Psychological Distress trials. A trial with sites in several states counts in each.

California 5 trials
Pennsylvania 3 trials
New York 3 trials
North Carolina 3 trials
Texas 2 trials
New Jersey 2 trials
Massachusetts 2 trials
Georgia 2 trials

Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.

What to do with this Psychological Distress page

29 registered trials, 12 currently recruiting, is a starting point for a conversation, not a diagnosis or a recommendation.

Trial and recruiting counts reflect ClinicalTrials.gov registry status as of the data vintage above; individual trial eligibility and enrollment status can change.

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This Psychological Distress condition card totals 29 registered trials; most-linked intervention Flourish; top US site state California. See our editorial standards & corrections policy, the methodology behind these numbers, the data changelog, or report a data error.