Medical Information Only. Always consult your healthcare provider before enrolling in any clinical trial.

NCT04112225 · ClinicalTrials.gov registry record · NA

Testing the Effectiveness of an Online Behavioral Intervention in Reducing Loneliness

A NA study of Loneliness and Psychological Distress, sponsored by Happify.

Completed
Registry status
NA
Development phase
890
Enrollment target
1
Study location

NCT04112225: Completed NA study of Loneliness and Psychological Distress, sponsored by Happify.

NCT04112225 is a NA study of Loneliness and Psychological Distress that has completed, run by Happify. The registered enrollment target is 890 participants, above the 384-participant average among 35 other Loneliness trials with a reported enrollment target (132% higher). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.

View on ClinicalTrials.gov ↗

View your shortlist →

The verdict

NCT04112225, a NA study of Loneliness and Psychological Distress, has completed, sponsored by Happify.

COMPLETED
Registry status
NA
Development phase
890 participants
Enrollment target
1
Study location

Study Summary

This study will use a longitudinal randomized experimental design. Participants will be randomly assigned to either a positive affect skills intervention or a psychoeducation control group and assessed with questionnaires at baseline and immediately post 8-week intervention.

Primary Outcome

A 20-item scale designed to measure one's subjective feelings of loneliness as well as feelings of social isolation.

Interventions

  • BEHAVIORAL Happify

Study Locations (1)

New York

  • Happify (an online platform -- study is entirely online) - New York

Trial Details

FieldValue
Enrollment Target 890 participants
Start Date 2019-08-01
Est. Completion 2020-03-25
Phase NA
Happify

6 total trials

What the finished NCT04112225 record still lists

NCT04112225 is an interventional study that assigns participants to a tested intervention. The registered 890 participants enrollment target is mid-sized for trials with a published cap, above the 384-participant average among 35 other Loneliness trials with a reported enrollment target (132% higher).

The record links to 2 conditions, with Loneliness appearing as the primary indexed condition, and to 1 intervention - of which Happify is the first listed.

NCT04112225 reports a single indexed study location in New York.

Frequently Asked Questions

What is clinical trial NCT04112225 about?

NCT04112225 is a clinical study titled "Testing the Effectiveness of an Online Behavioral Intervention in Reducing Loneliness". This study will use a longitudinal randomized experimental design. Participants will be randomly assigned to either a positive affect skills intervention or a psychoeducation control group and assessed with questionnaires at baseline and immediately post 8-week intervention.

What is the current status of trial NCT04112225?

This trial is currently completed. It is a NA study. The enrollment target is 890 participants. The study started on 2019-08-01. Estimated completion is 2020-03-25.

What conditions does trial NCT04112225 study?

This clinical trial studies the following conditions: Loneliness, Psychological Distress.

What interventions are being tested in trial NCT04112225?

The interventions under investigation include: Happify (BEHAVIORAL).

Who is sponsoring clinical trial NCT04112225?

This trial is sponsored by Happify, which has 6 total clinical trials registered on ClinicalTrials.gov.

Where is trial NCT04112225 being conducted?

This trial has 1 study location across New York. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

Similar trials for Loneliness

Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.

Where NCT04112225's enrollment target sits among peer trials

890 6th of 35 higher than 30 of 35 other Loneliness trials

participants (enrollment target), bucketed by value

Each bar is a band; taller bars hold more other Loneliness trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.

Source ClinicalTrials.gov registry export · 2026-08-08

Nationwide trials with similar profiles

Cross-condition peers matched on enrollment target and registry start date, not the same-condition list above.

Similar enrollment target

  • NCT03564340 · 890 participants · Phase 1

    Study of REGN4018 (Ubamatamab) Administered Alone or in Combination With Cemiplimab in Adult Patients With Recurrent Ovarian Cancer or Other Recurrent Mucin-16 Expressing (MUC16+) Cancers

  • NCT05855200 · 892 participants · Phase 3

    Study of Perioperative Dostarlimab in Participants With Untreated T4N0 or Stage III dMMR/MSI-H Resectable Colon Cancer

  • NCT04862663 · 895 participants · Phase 3

    Capivasertib + CDK4/6i + Fulvestrant for Advanced/Metastatic HR+/HER2- Breast Cancer (CAPItello-292)

  • NCT07196748 · 882 participants · Phase 3

    A Protocol of Icotrokinra Therapy in Adult and Adolescent Participants With Moderately to Severely Active Ulcerative Colitis

Similar registry start date

  • NCT05962346 · started 2026-12 · NA

    Fetal Endoscopic Tracheal Occlusion for Congenital Diaphragmatic Hernia

  • NCT07125183 · started 2026-12 · Phase 2

    Study on Efficacy and Tolerability of Weekly Doxorubicin in Elderly Patients With Advanced or Metastatic Leiomyosarcoma

  • NCT07292298 · started 2026-11 · Phase 2

    Phase 2 Single-Arm Rectal Cancer Brachytherapy for Patients With Low-Lying Residual Adenocarcinoma After Total Neoadjuvant Therapy to Improve Organ Preservation Rates

  • NCT04263285 · started 2026-10 · NA

    Treatment of Depression Post-SCI

Source: ClinicalTrials.gov NCT04112225, the US trial registry maintained by the National Library of Medicine. NCT04112225 (mid enrollment · single site footprint · completed) retrieved and formatted by PlainTrial, see methodology.