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Premature Birth: full-pipeline trial registry
21 of 39 indexed Premature Birth trials are currently recruiting.
Corpus placement: #382 of 28,707 conditions by registered trial count.
39 US clinical trials · 21 currently recruiting · #382 of 28,707 conditions by registered trial count
Premature Birth: 39 US clinical trials tracked, 21 recruiting.
Premature Birth is the subject of 39 registered US clinical trials on ClinicalTrials.gov, 21 of them currently open to new participants. 3 are in Phase 3-4 (later-stage) and 2 in Phase 1-2 (earlier-stage). The most active sponsor is Ann & Robert H Lurie Children's Hospital of Chicago, running 3 of these trials.
Enrollment posture brief
Registry condition premature-birth
OPEN 21 | RECR 54% | LATE 3 | EARLY 2 | RANK #382 | SPON 3
Volume-matched condition peers
Nearest open-share peer: Advanced Renal Cell Carcinoma (54% recruiting · 13 trials)
Premature Birth lists 21 open slots (54% of 39 indexed trials). Peers are matched on registered volume, not therapeutic-area browse lists. How peer matching works →
Key findings
What ClinicalTrials.gov does not surface for Premature Birth on its own pages , computed from the registry mirror as of 2026-08-08. Each line carries its own denominator so it can be quoted as it stands.
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Premature Birth is recruiting above its size-band peers.
21 of 39 indexed trials (53.8%) are open to enrollment, against a 39.7% average across 762 conditions with 20-99 trials. The peer set uses the same ClinicalTrials.gov-derived counts as this page.
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Sponsorship of Premature Birth trials is spread across many organizations.
Ann & Robert H Lurie Children's Hospital of Chicago accounts for 3 of 39 trials (7.7%). 33 distinct sponsors appear on at least one study for this condition label.
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Typical Premature Birth enrolment sits around 120 participants.
Median target enrolment is 120 among the 39 trials that report a genuine target (sentinel values excluded). 17 of those (43.6%) plan for fewer than 100 participants.
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Premature Birth research is mostly interventional.
28 interventional and 11 observational studies make up this index (71.8% interventional). Study type is sponsor-reported on ClinicalTrials.gov.
Open and recent trials
39 total, page 1 of 1
Multisite Inventory of Neonatal-Perinatal Interventions (MINI) Minimum Dataset
The University of Texas Health Science Center, Houston
NCT05685745
PPROM Registry (Preterm Premature Rupture of Membranes)
American Alliance for pProm Support
NCT02997345
Fresh RX: NHS 2020
Washington University School of Medicine
NCT04845230
Post-Vent, the Sequelae: Personalized Prognostic Modeling for Consequences of Neonatal Intermittent Hypoxemia in Preterm Infants at Pre-School Age
Ann & Robert H Lurie Children's Hospital of Chicago
NCT05336890
Optimizing Family Counseling for Anticipated Extremely Preterm Delivery
Boston Children's Hospital
NCT03819933
LATe Cerclage in High-risk Pregnancies (LATCH)
Thomas Jefferson University
NCT06036446
A Randomized Control Trial of a Responsive Parenting Intervention to Support Healthy Brain Development and Self-regulation in Toddlers Born Preterm
The University of Texas Health Science Center, Houston
NCT04856501
Effects of a Physical Therapy Intervention on Motor Delay in Infants Admitted to a Neonatal Intensive Care Unit
Shirley Ryan AbilityLab
NCT05568264
The Periviable GOALS Decision Support Tool
Indiana University
NCT05264779
Development of a Therapeutic Device to Improve Speech Sound Differentiation in Preterm Infants
Thrive Neuromedical
NCT06063122
Prophylactic Minimally Invasive Surfactant Evaluation
Endeavor Health
NCT06007547
Nourishing Beginnings: Addressing Food Insecurity During Pregnancy
Case Western Reserve University
NCT05341960
Growing Little PEAPODS Study
University of Wisconsin, Madison
NCT06226051
Healing Tiny Minds: Rural Recovery Through Virtual and Lived Experience Care
University of Wisconsin, Madison
NCT06643598
Biomarkers Study in Infants With Prior Neonatal Brain Injury
University of Wisconsin, Madison
NCT07413900
Outpatient Antibiotics Following Previable Rupture of Membranes (pPPROM) Between 18 0/7 and 22 6/7 Weeks Gestational Age
University Hospitals Cleveland Medical Center
NCT05345457
Childhood Outcomes of Preterm Brain Abnormalities
Children's Hospital Los Angeles
NCT03410810
A Randomized Controlled Trial of Impact of Wearable, Wireless Breast Pumps on Frequency and Efficacy of Milk Expression in Mothers of Premature Infants
University of Texas at Austin
NCT06723067
Postpartum Care in the NICU (PeliCaN) Transitions
University of Pennsylvania
NCT06521398
Spinal Stimulation and Mobility Devices
University of Washington
NCT05520359
taVNS-Paired Breastfeeding to Improve Breastfeeding at Discharge
Medical University of South Carolina
NCT06417385
Parent Training for Parents of Toddlers Born Very Premature:
Ohio State University
NCT05217615
Prophylactic DR-CPAP on Late Preterm Infants Born by C-section: an RCT
University of Oklahoma
NCT05204719
Local Version of the Multi-center PREVENT Study Evaluating Cardio-respiratory Instability in Premature Infants
Ann & Robert H Lurie Children's Hospital of Chicago
NCT03655639
Listening to Mom 2: Neural, Clinical and Language Outcomes
Stanford University
NCT04193579
Exploring the Feasibility of Centering Pregnancy With Care Navigation
University of Arkansas
NCT05645549
Effect of Presenting Survival Information as Text or Pictograph During Periviable Birth Counseling
Medical College of Wisconsin
NCT04859114
Delayed Clamping and Milking the Umbilical Cord in Preterm Infants
TriHealth
NCT02092103
Welch Emotional Connection Screen (WECS) in the NICU
Columbia University
NCT04922242
Randomized Trial Comparing Misoprostol and Foley Bulb for Labor Induction in the Preterm Gestation
University of Florida
NCT00325026
Maternal Effects of Bacterial Vaginosis (BV) Treatment in Pregnancy
Centers for Disease Control and Prevention
NCT00153517
Comparing Rater Reliability of Familiar Practitioners to Blinded Coders
Columbia University
NCT03680157
Improving Brain Development in Medically Healthy Premature Infants
Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)
NCT00065364
Evaluating the Effects of Kangaroo Care in the NICU
Ann & Robert H Lurie Children's Hospital of Chicago
NCT04727125
Meditation for NICU Moms
St. Louis University
NCT03574766
Indomethacin PK and PD Therapy in Pregnancy
The University of Texas Medical Branch, Galveston
NCT02451228
Pilot Trial of CenteringPregnancy With Mindfulness Skills
University of California, San Francisco
NCT01646463
17OHP-C Dosing Among Obese Pregnant Women
University of South Florida
NCT03433040
Impact of Currently Recommended Postnatal Nutrition on Neonatal Body Composition
Vishal Pandey, M.D.
NCT02622373
Phase Distribution
| Phase | Trial count |
|---|---|
| Phase 2 | 2 |
| Phase 3 | 1 |
| Phase 4 | 2 |
Top Sponsors
Named interventions
Most-linked intervention names on Premature Birth records (sponsor-reported on ClinicalTrials.gov). Counts are trial links, not unique products.
US sites by state
Facility locations filed on Premature Birth trials. A trial with sites in several states counts in each.
Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.
Related
What to do with this Premature Birth page
39 registered trials, 21 currently recruiting, is a starting point for a conversation, not a diagnosis or a recommendation.
- 21 Premature Birth trials are currently recruiting, check eligibility criteria before contacting a site. Browse recruiting trials
- Ann & Robert H Lurie Children's Hospital of Chicago sponsors the most Premature Birth trials on record, review their full trial history before evaluating a specific study. See Ann & Robert H Lurie Children's Hospital of Chicago's trials
- Bring the specific trial ID (NCT number) to your own doctor before enrolling, this page is a directory, not medical guidance. Read the trial-finding guide
Trial and recruiting counts reflect ClinicalTrials.gov registry status as of the data vintage above; individual trial eligibility and enrollment status can change.
Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This Premature Birth condition card totals 39 registered trials; most-linked intervention Newborn Individualized Developmental Care Assessment Program; top US site state Illinois. See our editorial standards & corrections policy, the methodology behind these numbers, the data changelog, or report a data error.