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NCT00759707 · ClinicalTrials.gov registry record · NA
Endothelial Function in Lower Extremity Bypass Grafts
A NA study of Peripheral Arterial Disease, sponsored by Brigham and Women's Hospital.
- Completed
- Registry status
- NA
- Development phase
- 19
- Enrollment target
- 1
- Study location
NCT00759707: Completed NA study of Peripheral Arterial Disease, sponsored by Brigham and Women's Hospital.
NCT00759707 is a NA study of Peripheral Arterial Disease that has completed, run by Brigham and Women's Hospital. The registered enrollment target is 19 participants, below the 4,206-participant average among 79 other Peripheral Arterial Disease trials with a reported enrollment target (100% lower). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT00759707, a NA study of Peripheral Arterial Disease, has completed, sponsored by Brigham and Women's Hospital.
- COMPLETED
- Registry status
- NA
- Development phase
- 19 participants
- Enrollment target
- 1
- Study location
Study Summary
This study will determine whether or not saphenous vein \[arterial\] bypass grafts in the leg relax in response to increases in blood flow.
Primary Outcome
Flow-mediated, endothelium-dependent vasodilation was determined by comparing baseline vein graft diameter with vein graft diameter as measured after deflation of a 2.5-inch wide sphygmomanometric cuff that had been inflated to suprasystolic pressure for 5 minutes. The cuff was never placed directly over the graft. Vasodilation of the vein graft was determined by acquiring images at 1 minute after cuff deflation.
Conditions Studied
Interventions
- DRUG L-N^G monomethyl arginine (L-NMMA)
Study Locations (1)
Massachusetts
- Brigham and Women's Hospital - Boston
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 19 participants |
| Start Date | 2006-04 |
| Est. Completion | 2009-12 |
| Phase | NA |
What the finished NCT00759707 record still lists
NCT00759707 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 19 participants, a relatively small participant target, below the 4,206-participant average among 79 other Peripheral Arterial Disease trials with a reported enrollment target (100% lower).
The record links to 1 condition, with Peripheral Arterial Disease appearing as the primary indexed condition, and to 1 intervention - of which L-N^G monomethyl arginine (L-NMMA) is the first listed.
NCT00759707 reports a single indexed study location in Massachusetts.
Frequently Asked Questions
What is clinical trial NCT00759707 about?
NCT00759707 is a clinical study titled "Endothelial Function in Lower Extremity Bypass Grafts". This study will determine whether or not saphenous vein \[arterial\] bypass grafts in the leg relax in response to increases in blood flow.
What is the current status of trial NCT00759707?
This trial is currently completed. It is a NA study. The enrollment target is 19 participants. The study started on 2006-04. Estimated completion is 2009-12.
What conditions does trial NCT00759707 study?
This clinical trial studies the following conditions: Peripheral Arterial Disease.
What interventions are being tested in trial NCT00759707?
The interventions under investigation include: L-N^G monomethyl arginine (L-NMMA) (DRUG).
Who is sponsoring clinical trial NCT00759707?
This trial is sponsored by Brigham and Women's Hospital, which has 937 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT00759707 being conducted?
This trial has 1 study location across Massachusetts. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
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Where NCT00759707's enrollment target sits among peer trials
19 69th of 79 higher than 11 of 79 other Peripheral Arterial Disease trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Peripheral Arterial Disease trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
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