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Patellofemoral Pain Syndrome clinical trials
Every US clinical trial registered for Patellofemoral Pain Syndrome — phase mix, recruiting status, and the sponsors running them, straight from the NIH ClinicalTrials.gov registry.
11 US clinical trials · 6 currently recruiting
The research picture
Patellofemoral Pain Syndrome has 11 registered US clinical trials, 6 of them open to new participants right now — about 55% of the total.
- 6
- recruiting participants now
- 55%
- of trials open to enrollment
- 1
- in Phase 3–4 (later-stage)
- 2
- top sponsor: National Institutes of Health Clinical Center (CC)
Counts reflect the public ClinicalTrials.gov registry as last mirrored by PlainTrial. Status and phase are reported by each study's sponsor. This is reference information, not medical advice.
Active & Recent Trials
MRI Study of Musculoskeletal Function
National Institutes of Health Clinical Center (CC)
NCT00051857
Emovi 3D Knee Assessment Device Intervention for Operational Readiness
Womack Army Medical Center
NCT06517056
The Effects of Dry Needling on Patients With Knee Pain
Ohio State University
NCT02890485
Comparing the Outcome of Electrical Stimulation and Physical Therapy in Patellofemoral Pain Syndrome
Northwell Health
NCT03184545
Modulating Cortical Excitability to Improve Functional Movements in Individuals With Patellofemoral Pain
University of Nevada, Las Vegas
NCT06565520
Mindful Miles Pilot Feasibility Study
University of North Carolina, Chapel Hill
NCT07462429
Trial of Neurostimulation and Blood Flow Restriction for PFPS in Active Duty
University of Tennessee
NCT04086615
Evaluation of a Treatment Algorithm for Patients With Patellofemoral Pain Syndrome
Nationwide Children's Hospital
NCT02461095
Protonics Knee Brace Versus Hamstring Resisted Exercise (HRE) on Individuals With Patellofemoral Pain Syndrome
Loma Linda University
NCT03042559
Muscle Strength Loss and Its Effect on Knee Cap Motion in Volunteers With Anterior Knee Pain
National Institutes of Health Clinical Center (CC)
NCT01862731
Utilizing the Trunk as a Proximal Lever to Strengthen the Hip Musculature and Alter Lower Extremity Function
High Point University
NCT03285464
Phase Distribution
| Phase | Trial count |
|---|---|
| Phase 3 | 1 |
Top Sponsors
Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.
Reading the Patellofemoral Pain Syndrome Trial Landscape
ClinicalTrials.gov lists 11 US studies indexed under Patellofemoral Pain Syndrome, and 6 of those are currently open to recruitment — roughly 55% of the total volume on the registry. That ratio is a useful proxy for activity level: a high share of recruiting studies often signals that research interest is current and that new enrollment opportunities are appearing, while a low share typically means the field is dominated by completed or follow-up work where most participant spots have already been filled. These counts reflect the public registry only and include studies at every stage of design, so they should be read as an index of research attention rather than as a measure of treatment availability.
The phase distribution for Patellofemoral Pain Syndrome shows 1 late-stage studies (Phase 3 and Phase 4 combined) alongside 0 earlier-phase entries (Phase 1 through Phase 2). Phase 1 and Phase 2 studies focus on early safety signals, dosing, and preliminary effect, while Phase 3 studies are typically the larger efficacy and safety trials submitted toward regulatory review, and Phase 4 studies follow approved interventions in real-world use. A condition weighted toward later phases often reflects a mature research pipeline with several interventions already close to or past approval, whereas a heavier early-phase tilt suggests the field is still exploring new mechanisms and candidate approaches.
Top sponsor activity for Patellofemoral Pain Syndrome is led by National Institutes of Health Clinical Center (CC) with 2 indexed trials, alongside 9 other organizations in the top contributor list. The list on this page surfaces up to 11 of the most relevant recent and active entries, ordered with recruiting studies first so practical options are visible. All figures are derived from the public ClinicalTrials.gov dataset maintained by the National Library of Medicine and are reproduced here for reference. Inclusion of a trial, sponsor, or intervention on this page is neither an endorsement nor a recommendation — eligibility, protocol changes, and site-level status can shift frequently, so always verify current details on ClinicalTrials.gov and consult a qualified healthcare provider before acting on anything you see here.
Frequently Asked Questions
How many clinical trials are there for Patellofemoral Pain Syndrome?
PlainTrial tracks 11 US clinical trials for Patellofemoral Pain Syndrome, of which 6 are currently recruiting participants. Data sourced from ClinicalTrials.gov.
How do I find a recruiting trial for Patellofemoral Pain Syndrome?
Use the trial list above filtered by "Recruiting" status, or visit our trial finder at /recruiting to search by condition and state. Always discuss trial participation with your healthcare provider before enrolling.
Is this data current?
Data is sourced from ClinicalTrials.gov and reflects our most recent data pull. Trial status may have changed since then. Always verify current information at ClinicalTrials.gov before making decisions about participation.
Related
Disclaimer: This information is provided for informational purposes only and does not constitute professional advice. Data is sourced from ClinicalTrials.gov (National Library of Medicine). Consult a qualified professional before making decisions based on this data.
Read our methodology — how this data is sourced, computed, and verified.
Source: ClinicalTrials.gov (NIH/NLM) ClinicalTrials.gov AACT registry · 2026 Trial counts and statuses sourced from ClinicalTrials.gov. Sponsor counts include both industry and federal/academic sponsors.