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ClinicalTrials.gov 6 recruiting now official registry

Patellofemoral Pain Syndrome clinical trials

6 of 11 indexed Patellofemoral Pain Syndrome trials are currently recruiting.

11 US clinical trials · 6 currently recruiting

Patellofemoral Pain Syndrome is the subject of 11 registered US clinical trials on ClinicalTrials.gov, 6 of them currently open to new participants. 1 are in Phase 3-4 (later-stage) and 0 in Phase 1-2 (earlier-stage). The most active sponsor is National Institutes of Health Clinical Center (CC), running 2 of these trials.

The research picture

Patellofemoral Pain Syndrome has 11 registered US clinical trials, 6 of them open to new participants right now, about 55% of the total.

6
recruiting participants now
55%
of trials open to enrollment
1
in Phase 3–4 (later-stage)
2
top sponsor: National Institutes of Health Clinical Center (CC)
Phase 31

Active & Recent Trials

11 total, page 1 of 1

RECRUITING 750 participants

MRI Study of Musculoskeletal Function

National Institutes of Health Clinical Center (CC)

NCT00051857

RECRUITING NA 180 participants

Emovi 3D Knee Assessment Device Intervention for Operational Readiness

Womack Army Medical Center

NCT06517056

RECRUITING NA 120 participants

The Effects of Dry Needling on Patients With Knee Pain

Ohio State University

NCT02890485

RECRUITING Phase 3 92 participants

Comparing the Outcome of Electrical Stimulation and Physical Therapy in Patellofemoral Pain Syndrome

Northwell Health

NCT03184545

RECRUITING NA 50 participants

Modulating Cortical Excitability to Improve Functional Movements in Individuals With Patellofemoral Pain

University of Nevada, Las Vegas

NCT06565520

RECRUITING NA 20 participants

Mindful Miles Pilot Feasibility Study

University of North Carolina, Chapel Hill

NCT07462429

COMPLETED NA 84 participants

Trial of Neurostimulation and Blood Flow Restriction for PFPS in Active Duty

University of Tennessee

NCT04086615

COMPLETED NA 55 participants

Evaluation of a Treatment Algorithm for Patients With Patellofemoral Pain Syndrome

Nationwide Children's Hospital

NCT02461095

COMPLETED NA 43 participants

Protonics Knee Brace Versus Hamstring Resisted Exercise (HRE) on Individuals With Patellofemoral Pain Syndrome

Loma Linda University

NCT03042559

COMPLETED 35 participants

Muscle Strength Loss and Its Effect on Knee Cap Motion in Volunteers With Anterior Knee Pain

National Institutes of Health Clinical Center (CC)

NCT01862731

COMPLETED NA 32 participants

Utilizing the Trunk as a Proximal Lever to Strengthen the Hip Musculature and Alter Lower Extremity Function

High Point University

NCT03285464

Phase Distribution

PhaseTrial count
Phase 3 1

Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.

Reading the Patellofemoral Pain Syndrome Trial Landscape

11 indexed Patellofemoral Pain Syndrome studies · 6 recruiting (55%).

Phase mix: 1 late (III/IV) vs 0 early (I/II).

Top sponsor: National Institutes of Health Clinical Center (CC) (2 trials), 9 others listed. 11 shown below, recruiting first.

How to read this condition's trial landscape

That ratio is a useful proxy for activity level: a high share of recruiting studies often signals that research interest is current and that new enrollment opportunities are appearing, while a low share typically means the field is dominated by completed or follow-up work where most participant spots have already been filled. These counts reflect the public registry only and include studies at every stage of design, so they should be read as an index of research attention rather than as a measure of treatment availability.

Phase 1 and Phase 2 studies focus on early safety signals, dosing, and preliminary effect, while Phase 3 studies are typically the larger efficacy and safety trials submitted toward regulatory review, and Phase 4 studies follow approved interventions in real-world use. A condition weighted toward later phases often reflects a mature research pipeline with several interventions already close to or past approval, whereas a heavier early-phase tilt suggests the field is still exploring new mechanisms and candidate approaches.

All figures are derived from the public ClinicalTrials.gov dataset maintained by the National Library of Medicine and are reproduced here for reference. Inclusion of a trial, sponsor, or intervention on this page is neither an endorsement nor a recommendation, eligibility, protocol changes, and site-level status can shift frequently, so always verify current details on ClinicalTrials.gov and consult a qualified healthcare provider before acting on anything you see here.

Frequently Asked Questions

How many clinical trials are there for Patellofemoral Pain Syndrome?

PlainTrial tracks 11 US clinical trials for Patellofemoral Pain Syndrome, of which 6 are currently recruiting participants. Data sourced from ClinicalTrials.gov.

How do I find a recruiting trial for Patellofemoral Pain Syndrome?

Use the trial list above filtered by "Recruiting" status, or visit our trial finder at /recruiting to search by condition and state. Always discuss trial participation with your healthcare provider before enrolling.

Is this data current?

Data is sourced from ClinicalTrials.gov and reflects our most recent data pull. Trial status may have changed since then. Always verify current information at ClinicalTrials.gov before making decisions about participation.

Disclaimer: This information is provided for informational purposes only and does not constitute professional advice. Data is sourced from ClinicalTrials.gov (National Library of Medicine). Consult a qualified professional before making decisions based on this data.

Source: ClinicalTrials.gov (NIH/NLM) ClinicalTrials.gov AACT registry · 2026 Trial counts and statuses sourced from ClinicalTrials.gov. Sponsor counts include both industry and federal/academic sponsors.

Verify with NIH →

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page aggregates every registered trial for this condition, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.