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ClinicalTrials.gov 6 recruiting now later-stage tilt small index

Patellofemoral Pain Syndrome: later-stage trial registry

6 of 11 indexed Patellofemoral Pain Syndrome trials are currently recruiting, with more weight in Phase 3-4.

Corpus placement: #1,577 of 28,707 conditions by registered trial count.

11 US clinical trials · 6 currently recruiting · #1,577 of 28,707 conditions by registered trial count

Patellofemoral Pain Syndrome: 11 US clinical trials tracked, 6 recruiting.

Patellofemoral Pain Syndrome is the subject of 11 registered US clinical trials on ClinicalTrials.gov, 6 of them currently open to new participants. 1 are in Phase 3-4 (later-stage) and 0 in Phase 1-2 (earlier-stage). The most active sponsor is National Institutes of Health Clinical Center (CC), running 2 of these trials.

Enrollment posture brief

Registry condition patellofemoral-pain-syndrome

OPEN 6 | RECR 55% | LATE 1 | EARLY 0 | RANK #1577 | SPON 2

Nearest open-share peer: Advanced Ovarian Carcinoma (55% recruiting · 11 trials)

Acute Pancreatitis81.8%Patellofemoral Pain Synd (th…55%Acute Stroke45.5%Acquired Brain Injury36.4%Acute Lung Injury9.1%
Open-enrollment share among volume-matched conditions near Patellofemoral Pain Syndrome

Patellofemoral Pain Syndrome lists 6 open slots (55% of 11 indexed trials). Peers are matched on registered volume, not therapeutic-area browse lists. How peer matching works →

Key findings

What ClinicalTrials.gov does not surface for Patellofemoral Pain Syndrome on its own pages , computed from the registry mirror as of 2026-08-08. Each line carries its own denominator so it can be quoted as it stands.

  1. Patellofemoral Pain Syndrome is recruiting above its size-band peers.

    6 of 11 indexed trials (54.5%) are open to enrollment, against a 46.5% average across 27,806 conditions with fewer than 20 trials. The peer set uses the same ClinicalTrials.gov-derived counts as this page.

  2. One sponsor concentrates Patellofemoral Pain Syndrome research.

    National Institutes of Health Clinical Center (CC) accounts for 2 of 11 trials (18.2%). 10 distinct sponsors appear on at least one study for this condition label.

  3. Most Patellofemoral Pain Syndrome trials plan to enrol fewer than 100 people.

    Median target enrolment is 55 among the 11 trials that report a genuine target (sentinel values excluded). 8 of those (72.7%) plan for fewer than 100 participants.

  4. Patellofemoral Pain Syndrome research is mostly interventional.

    9 interventional and 2 observational studies make up this index (81.8% interventional). Study type is sponsor-reported on ClinicalTrials.gov.

Phase 31

Open and recent trials

11 total, page 1 of 1

RECRUITING 750 participants

MRI Study of Musculoskeletal Function

National Institutes of Health Clinical Center (CC)

NCT00051857

RECRUITING NA 180 participants

Emovi 3D Knee Assessment Device Intervention for Operational Readiness

Womack Army Medical Center

NCT06517056

RECRUITING NA 120 participants

The Effects of Dry Needling on Patients With Knee Pain

Ohio State University

NCT02890485

RECRUITING Phase 3 92 participants

Comparing the Outcome of Electrical Stimulation and Physical Therapy in Patellofemoral Pain Syndrome

Northwell Health

NCT03184545

RECRUITING NA 50 participants

Modulating Cortical Excitability to Improve Functional Movements in Individuals With Patellofemoral Pain

University of Nevada, Las Vegas

NCT06565520

RECRUITING NA 20 participants

Mindful Miles Pilot Feasibility Study

University of North Carolina, Chapel Hill

NCT07462429

COMPLETED NA 84 participants

Trial of Neurostimulation and Blood Flow Restriction for PFPS in Active Duty

University of Tennessee

NCT04086615

COMPLETED NA 55 participants

Evaluation of a Treatment Algorithm for Patients With Patellofemoral Pain Syndrome

Nationwide Children's Hospital

NCT02461095

COMPLETED NA 43 participants

Protonics Knee Brace Versus Hamstring Resisted Exercise (HRE) on Individuals With Patellofemoral Pain Syndrome

Loma Linda University

NCT03042559

COMPLETED 35 participants

Muscle Strength Loss and Its Effect on Knee Cap Motion in Volunteers With Anterior Knee Pain

National Institutes of Health Clinical Center (CC)

NCT01862731

COMPLETED NA 32 participants

Utilizing the Trunk as a Proximal Lever to Strengthen the Hip Musculature and Alter Lower Extremity Function

High Point University

NCT03285464

Phase Distribution

PhaseTrial count
Phase 3 1

Named interventions

Most-linked intervention names on Patellofemoral Pain Syndrome records (sponsor-reported on ClinicalTrials.gov). Counts are trial links, not unique products.

PFPS Algorithm approach Other
1 trials
Impairment based approach Other
1 trials
Sports Cords Device
1 trials
Protonics Knee brace Device
1 trials
Triplanar Rotary Resistance Other
1 trials
NMES and exercise supplemented with low BFR Device
1 trials
NMES and exercise supplemented with high BFR Device
1 trials
EMS Device
1 trials

US sites by state

Facility locations filed on Patellofemoral Pain Syndrome trials. A trial with sites in several states counts in each.

North Carolina 3 trials
Ohio 2 trials
Maryland 2 trials
New York 1 trials
Nevada 1 trials
Kentucky 1 trials
Hawaii 1 trials
California 1 trials

Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.

What to do with this Patellofemoral Pain Syndrome page

11 registered trials, 6 currently recruiting, is a starting point for a conversation, not a diagnosis or a recommendation.

Trial and recruiting counts reflect ClinicalTrials.gov registry status as of the data vintage above; individual trial eligibility and enrollment status can change.

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This Patellofemoral Pain Syndrome condition card totals 11 registered trials; most-linked intervention PFPS Algorithm approach; top US site state North Carolina. See our editorial standards & corrections policy, the methodology behind these numbers, the data changelog, or report a data error.