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ClinicalTrials.gov 8 recruiting now early-phase tilt

Opioid-Related Disorders: early-phase trial registry

8 of 59 indexed Opioid-Related Disorders trials are currently recruiting, with more weight in Phase 1-2.

Corpus placement: #241 of 28,707 conditions by registered trial count.

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59 US clinical trials · 8 currently recruiting · #241 of 28,707 conditions by registered trial count

Opioid-Related Disorders: 59 US clinical trials tracked, 8 recruiting.

Opioid-Related Disorders is the subject of 59 registered US clinical trials on ClinicalTrials.gov, 8 of them currently open to new participants. 10 are in Phase 3-4 (later-stage) and 25 in Phase 1-2 (earlier-stage). The most active sponsor is National Institute on Drug Abuse (NIDA), running 10 of these trials.

Enrollment posture brief

Registry condition opioid-related-disorders

OPEN 8 | RECR 14% | LATE 10 | EARLY 25 | RANK #241 | SPON 10

Volume-matched condition peers

Nearest open-share peer: Chronic Myeloproliferative Disorders (14% recruiting · 22 trials)

Anatomic Stage IV Breast Can70%Hearing Loss50%HER2-positive Breast Cancer47.5%Substance Abuse15.3%Opioid-Related Disorders (th…14%
Open-enrollment share among volume-matched conditions near Opioid-Related Disorders

Opioid-Related Disorders lists 8 open slots (14% of 59 indexed trials). Peers are matched on registered volume, not therapeutic-area browse lists. How peer matching works →

Key findings

What ClinicalTrials.gov does not surface for Opioid-Related Disorders on its own pages , computed from the registry mirror as of 2026-08-08. Each line carries its own denominator so it can be quoted as it stands.

  1. Opioid-Related Disorders is recruiting below its size-band peers.

    8 of 59 indexed trials (13.6%) are open to enrollment, against a 39.7% average across 762 conditions with 20-99 trials. The peer set uses the same ClinicalTrials.gov-derived counts as this page.

  2. One sponsor concentrates Opioid-Related Disorders research.

    National Institute on Drug Abuse (NIDA) accounts for 10 of 59 trials (16.9%). 38 distinct sponsors appear on at least one study for this condition label.

  3. Typical Opioid-Related Disorders enrolment sits around 140 participants.

    Median target enrolment is 140 among the 48 trials that report a genuine target (sentinel values excluded). 22 of those (45.8%) plan for fewer than 100 participants.

  4. Opioid-Related Disorders research is mostly interventional.

    52 interventional and 7 observational studies make up this index (88.1% interventional). Study type is sponsor-reported on ClinicalTrials.gov.

Phase 16Phase 219Phase 37Phase 43

Phase Distribution

PhaseTrial count
Phase 1 6
Phase 2 19
Phase 3 7
Phase 4 3

Top Sponsors

National Institute on Drug Abuse (NIDA) 10 trials
Indivior 4 trials
University of Vermont 4 trials
T. John Winhusen, PhD 3 trials
New York State Psychiatric Institute 2 trials
University of Pittsburgh 2 trials
Yale University 2 trials
University of Chicago 2 trials
Acura Pharmaceuticals 1 trials
Jennifer Havens 1 trials

Named interventions

Most-linked intervention names on Opioid-Related Disorders records (sponsor-reported on ClinicalTrials.gov). Counts are trial links, not unique products.

Buprenorphine Drug
11 trials
Buprenorphine Sublingual Product Drug
3 trials
Buprenorphine/naloxone Drug
3 trials
Buprenorphine Injection Drug
3 trials
RBP-6000 Drug
2 trials
40% N2O Drug
2 trials
Placebo Drug
2 trials
Generic H/A plus p taken first Drug
1 trials

US sites by state

Facility locations filed on Opioid-Related Disorders trials. A trial with sites in several states counts in each.

California 10 trials
Pennsylvania 9 trials
Massachusetts 9 trials
Florida 8 trials
Vermont 7 trials
Utah 7 trials
Washington 6 trials
Ohio 6 trials

Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.

Related

Read our methodology - how this data is sourced, computed, and verified.

What to do with this Opioid-Related Disorders page

59 registered trials, 8 currently recruiting, is a starting point for a conversation, not a diagnosis or a recommendation.

Trial and recruiting counts reflect ClinicalTrials.gov registry status as of the data vintage above; individual trial eligibility and enrollment status can change.

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This Opioid-Related Disorders condition card totals 59 registered trials; most-linked intervention Buprenorphine; top US site state California. See our editorial standards & corrections policy, the methodology behind these numbers, the data changelog, or report a data error.