Medical Information Only. Consult your healthcare provider before considering clinical trial enrollment.
Opioid Overdose: later-stage trial registry
6 of 9 indexed Opioid Overdose trials are currently recruiting, with more weight in Phase 3-4.
Corpus placement: #1,916 of 28,707 conditions by registered trial count.
9 US clinical trials · 6 currently recruiting · #1,916 of 28,707 conditions by registered trial count
Opioid Overdose: 9 US clinical trials tracked, 6 recruiting.
Opioid Overdose is the subject of 9 registered US clinical trials on ClinicalTrials.gov, 6 of them currently open to new participants. 2 are in Phase 3-4 (later-stage) and 1 in Phase 1-2 (earlier-stage). The most active sponsor is Kaiser Permanente, running 1 of these trials.
Enrollment posture brief
Registry condition opioid-overdose
OPEN 6 | RECR 67% | LATE 2 | EARLY 1 | RANK #1916 | SPON 1
Volume-matched condition peers
Nearest open-share peer: Acute Hypoxemic Respiratory Failure (67% recruiting · 6 trials)
Opioid Overdose lists 6 open slots (67% of 9 indexed trials). Peers are matched on registered volume, not therapeutic-area browse lists. How peer matching works →
Key findings
What ClinicalTrials.gov does not surface for Opioid Overdose on its own pages , computed from the registry mirror as of 2026-08-08. Each line carries its own denominator so it can be quoted as it stands.
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Opioid Overdose is recruiting above its size-band peers.
6 of 9 indexed trials (66.7%) are open to enrollment, against a 46.5% average across 27,806 conditions with fewer than 20 trials. The peer set uses the same ClinicalTrials.gov-derived counts as this page.
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Sponsorship of Opioid Overdose trials is spread across many organizations.
Kaiser Permanente accounts for 1 of 9 trials (11.1%). 9 distinct sponsors appear on at least one study for this condition label.
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Typical Opioid Overdose enrolment sits around 250 participants.
Median target enrolment is 250 among the 9 trials that report a genuine target (sentinel values excluded). 3 of those (33.3%) plan for fewer than 100 participants.
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Opioid Overdose splits between interventional and observational designs.
6 interventional and 3 observational studies make up this index (66.7% interventional). Study type is sponsor-reported on ClinicalTrials.gov.
Open and recent trials
9 total, page 1 of 1
Vending Machine Naloxone Distribution for Your Community (VENDY)
University of Colorado, Denver
NCT06429436
Machine-Learning Prediction and Reducing Overdoses With EHR Nudges
University of Pittsburgh
NCT06806163
Young Houston Emergency Opioid Engagement System
The University of Texas Health Science Center, Houston
NCT04811014
A Bundled Intervention
University of Alabama at Birmingham
NCT06593093
Improving Availability of Intranasal Naloxone
Hartford Hospital
NCT05877118
Quantitative Xylazine Measurement in ED
Icahn School of Medicine at Mount Sinai
NCT06949605
Health Insurance Instability and Mortality Among Patients Receiving Bup Tx for OUD
Kaiser Permanente
NCT05944133
Opioid Rapid Response System: Naloxone Training in Communities
University of Missouri-Columbia
NCT06238128
Development of a Tracheal Sound Sensor
Thomas Jefferson University
NCT05506267
Phase Distribution
| Phase | Trial count |
|---|---|
| Phase 1 | 1 |
| Phase 4 | 2 |
Top Sponsors
Named interventions
Most-linked intervention names on Opioid Overdose records (sponsor-reported on ClinicalTrials.gov). Counts are trial links, not unique products.
US sites by state
Facility locations filed on Opioid Overdose trials. A trial with sites in several states counts in each.
Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.
Related
What to do with this Opioid Overdose page
9 registered trials, 6 currently recruiting, is a starting point for a conversation, not a diagnosis or a recommendation.
- 6 Opioid Overdose trials are currently recruiting, check eligibility criteria before contacting a site. Browse recruiting trials
- Kaiser Permanente sponsors the most Opioid Overdose trials on record, review their full trial history before evaluating a specific study. See Kaiser Permanente's trials
- Bring the specific trial ID (NCT number) to your own doctor before enrolling, this page is a directory, not medical guidance. Read the trial-finding guide
Trial and recruiting counts reflect ClinicalTrials.gov registry status as of the data vintage above; individual trial eligibility and enrollment status can change.
Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This Opioid Overdose condition card totals 9 registered trials; most-linked intervention Trachea Sound Sensor (TSS); top US site state Pennsylvania. See our editorial standards & corrections policy, the methodology behind these numbers, the data changelog, or report a data error.