Medical Information Only. Consult your healthcare provider before considering clinical trial enrollment.
Opiate Dependence: full-pipeline trial registry
2 of 16 indexed Opiate Dependence trials are currently recruiting.
Corpus placement: #1,060 of 28,707 conditions by registered trial count.
16 US clinical trials · 2 currently recruiting · #1,060 of 28,707 conditions by registered trial count
Opiate Dependence: 16 US clinical trials tracked, 2 recruiting.
Opiate Dependence is the subject of 16 registered US clinical trials on ClinicalTrials.gov, 2 of them currently open to new participants. 3 are in Phase 3-4 (later-stage) and 4 in Phase 1-2 (earlier-stage). The most active sponsor is Yale University, running 3 of these trials.
Enrollment posture brief
Registry condition opiate-dependence
OPEN 2 | RECR 13% | LATE 3 | EARLY 4 | RANK #1060 | SPON 3
Volume-matched condition peers
Nearest open-share peer: Acute Respiratory Infection (13% recruiting · 8 trials)
Opiate Dependence lists 2 open slots (13% of 16 indexed trials). Peers are matched on registered volume, not therapeutic-area browse lists. How peer matching works →
Key findings
What ClinicalTrials.gov does not surface for Opiate Dependence on its own pages , computed from the registry mirror as of 2026-08-08. Each line carries its own denominator so it can be quoted as it stands.
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Opiate Dependence is recruiting below its size-band peers.
2 of 16 indexed trials (12.5%) are open to enrollment, against a 46.5% average across 27,806 conditions with fewer than 20 trials. The peer set uses the same ClinicalTrials.gov-derived counts as this page.
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One sponsor concentrates Opiate Dependence research.
Yale University accounts for 3 of 16 trials (18.8%). 13 distinct sponsors appear on at least one study for this condition label.
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Typical Opiate Dependence enrolment sits around 106 participants.
Median target enrolment is 106 among the 16 trials that report a genuine target (sentinel values excluded). 8 of those (50%) plan for fewer than 100 participants.
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Opiate Dependence research is mostly interventional.
15 interventional and 1 observational studies make up this index (93.8% interventional). Study type is sponsor-reported on ClinicalTrials.gov.
Open and recent trials
16 total, page 1 of 1
Substance Abuse Pre-Treatment Screening Study
The University of Texas Health Science Center, Houston
NCT00439049
Infusion of Lidocaine and Steroids in Middle Meningeal Artery for Pain in Subarachnoid Hemorrhage
The University of Texas Medical Branch, Galveston
NCT07294118
Study to Assess Efficacy and Safety of BNX Sublingual Tablets for the Induction of Treatment of Opioid Dependence
Orexo AB
NCT01848054
Reengineering Methadone Treatment Study of Patient-centered Methadone Treatment
Friends Research Institute
NCT01442493
Project FIRST - Financial Incentives to Reduce Substance Use and Improve Treatment
Albert Einstein College of Medicine
NCT01376570
Linking Hospitalized Injection Drug Users to Buprenorphine
Butler Hospital
NCT00987961
Clinical Efficacy of Disulfiram in LAAM-Maintained Cocaine Abusers
Yale University
NCT00580827
Comparison of HIV Clinic-based Treatment With Buprenorphine Versus Referred Care in Heroin-dependent Participants
Johns Hopkins University
NCT00130819
Cocaine Withdrawal and Pharmacotherapy Response
Yale University
NCT00566969
Behavioral Naltrexone Therapy for Promoting Adherence to Oral Naltrexone vs Extended Release Injectable Depot Naltrexone
New York State Psychiatric Institute
NCT00577408
Imaging Synaptic Density in Cocaine and Opiate Addiction In Vivo Using 11UCB-J PET
Yale University
NCT03527485
Project Relief: Developing Brain Stimulation as a Treatment for Chronic Pain
Wake Forest University Health Sciences
NCT04156802
Employment-Based Depot Naltrexone Clinical Trial II
Johns Hopkins University
NCT00684775
Neurobehavioral Measurement of Substance Users in Outpatient Treatment Setting
Hunter Holmes Mcguire Veteran Affairs Medical Center
NCT03662529
Remote Observed Dosing of Suboxone to Improve Clinical Practice
University of Pennsylvania
NCT03769025
Distress Tolerance and HIV Prevention With XR-NTX Initiation in Opioid Dependence
Rhode Island Hospital
NCT02602795
Phase Distribution
| Phase | Trial count |
|---|---|
| Phase 1 | 1 |
| Phase 2 | 3 |
| Phase 3 | 3 |
Top Sponsors
Named interventions
Most-linked intervention names on Opiate Dependence records (sponsor-reported on ClinicalTrials.gov). Counts are trial links, not unique products.
US sites by state
Facility locations filed on Opiate Dependence trials. A trial with sites in several states counts in each.
Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.
Related
What to do with this Opiate Dependence page
16 registered trials, 2 currently recruiting, is a starting point for a conversation, not a diagnosis or a recommendation.
- 2 Opiate Dependence trials are currently recruiting, check eligibility criteria before contacting a site. Browse recruiting trials
- Yale University sponsors the most Opiate Dependence trials on record, review their full trial history before evaluating a specific study. See Yale University's trials
- Bring the specific trial ID (NCT number) to your own doctor before enrolling, this page is a directory, not medical guidance. Read the trial-finding guide
Trial and recruiting counts reflect ClinicalTrials.gov registry status as of the data vintage above; individual trial eligibility and enrollment status can change.
Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This Opiate Dependence condition card totals 16 registered trials; most-linked intervention Carvedilol 50 mg; top US site state Maryland. See our editorial standards & corrections policy, the methodology behind these numbers, the data changelog, or report a data error.