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NCT00566969 · ClinicalTrials.gov registry record · NA

Cocaine Withdrawal and Pharmacotherapy Response

A NA study of Cocaine Dependence and Opiate Dependence, sponsored by Yale University.

Completed
Registry status
NA
Development phase
106
Enrollment target
1
Study location

NCT00566969 is a NA study of Cocaine Dependence and Opiate Dependence that has completed, run by Yale University. The registered enrollment target is 106 participants, below the 296-participant average among 38 other Cocaine Dependence trials with a reported enrollment target (64% lower). The trial reports 1 study location across 1 state.

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The verdict

NCT00566969, a NA study of Cocaine Dependence and Opiate Dependence, has completed, sponsored by Yale University.

COMPLETED
Registry status
NA
Development phase
106 participants
Enrollment target
1
Study location

Study Summary

A total of 120 male and female opioid dependent cocaine users will participate in this study. This study will be a 8-week double-blind, placebo controlled study examining the dose-dependent effects of carvedilol (up to 50 mg/day) in methadone stabilized patients. The design will have two phases: 1) a four-week "treatment " phase; and 2) a 4 week " taper and detoxification or transfer" phase. Subjects will be cocaine users who are on stable doses of methadone (60 to 140 mg/day). Carvedilol dose will be increased from 12.5mg/day to the target dose of either 25 or 50 mg/day as tolerated. At the end of the treatment-phase, subjects will undergo detoxification from methadone over a 2 to 4-week period based on an individual's needs, and they will concurrently be tapered off carvedilol.

Conditions Studied

Cocaine Dependence Opiate Dependence

Interventions

  • DRUG sugar pill
  • DRUG Carvedilol 25 mg
  • DRUG Carvedilol 50 mg

Study Locations (1)

Connecticut

  • Veterans Hospital - West Haven

Trial Details

FieldValue
Enrollment Target 106 participants
Start Date 2007-09
Est. Completion 2013-01
Phase NA

Sponsor

Yale University

1,492 total trials

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What the Registry Record Tells You About NCT00566969

The ClinicalTrials.gov registry entry for NCT00566969 describes a study currently listed as completed, categorized as NA. The registered enrollment target is 106 participants, a figure that helps gauge the scale of data the investigators plan to collect, below the 296-participant average among 38 other Cocaine Dependence trials with a reported enrollment target (64% lower). The listed sponsor is Yale University, which has 1,492 total studies on file at ClinicalTrials.gov.

The record links to 2 conditions, with Cocaine Dependence appearing as the primary indexed condition, and to 3 interventions - of which sugar pill is the first listed.

NCT00566969 reports 1 study location spanning 1 distinct geographic area - top geographies include Connecticut.

Frequently Asked Questions

What is clinical trial NCT00566969 about?

NCT00566969 is a clinical study titled "Cocaine Withdrawal and Pharmacotherapy Response". A total of 120 male and female opioid dependent cocaine users will participate in this study. This study will be a 8-week double-blind, placebo controlled study examining the dose-dependent effects of carvedilol (up to 50 mg/day) in methadone stabilized patients. The design will have two phases: 1) ...

What is the current status of trial NCT00566969?

This trial is currently completed. It is a NA study. The enrollment target is 106 participants. The study started on 2007-09. Estimated completion is 2013-01.

What conditions does trial NCT00566969 study?

This clinical trial studies the following conditions: Cocaine Dependence, Opiate Dependence.

What interventions are being tested in trial NCT00566969?

The interventions under investigation include: sugar pill (DRUG), Carvedilol 25 mg (DRUG), Carvedilol 50 mg (DRUG).

Who is sponsoring clinical trial NCT00566969?

This trial is sponsored by Yale University, which has 1,492 total clinical trials registered on ClinicalTrials.gov.

Where is trial NCT00566969 being conducted?

This trial has 1 study location across Connecticut. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

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Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page mirrors this trial's own ClinicalTrials.gov registry record, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.