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NCT00714129 · ClinicalTrials.gov registry record · NA
De Novo Lipogenesis, Lipid and Carbohydrate Metabolism in Non-alcoholic Fatty Liver Disease
A NA study of Diabetes and Non-alcoholic Fatty Liver Disease, sponsored by University of California, San Francisco.
- Completed
- Registry status
- NA
- Development phase
- 41
- Enrollment target
- 1
- Study location
NCT00714129: Completed NA study of Diabetes and Non-alcoholic Fatty Liver Disease, sponsored by University of California, San Francisco.
NCT00714129 is a NA study of Diabetes and Non-alcoholic Fatty Liver Disease that has completed, run by University of California, San Francisco. The registered enrollment target is 41 participants, below the 3,028-participant average among 338 other Diabetes trials with a reported enrollment target (99% lower). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT00714129, a NA study of Diabetes and Non-alcoholic Fatty Liver Disease, has completed, sponsored by University of California, San Francisco.
- COMPLETED
- Registry status
- NA
- Development phase
- 41 participants
- Enrollment target
- 1
- Study location
Study Summary
The worldwide epidemic of obesity is paralleled with increased cases of non-alcoholic liver disease (liver fat accumulation) and diabetes. Fat belongs in the adipose tissue, and if excess fat accumulates in the liver or muscle, these tissues cannot use sugar efficiently. It has been discovered that when large quantities of fructose (a sugar present in soft drinks) are consumed, the conversion of carbohydrate (CHO) to fat in the liver increases. We hypothesize that: 1) subjects with fatty liver have a higher CHO uptake and conversion to fat in their liver when compared to matched control subjects with normal liver fat content; and that: 2) when subjects with fatty liver are fed a diet limiting fructose and simple sugars will decrease their liver CHO fat content. This reduction in liver fat will normalize the way the liver responds to sugar and insulin, reversing the pre-diabetic state. The measurement of these parameters will be done using state-of-the-art techniques such as safe non-radioactive isotope tracers and non-invasive magnetic resonance spectroscopy. For more information, please call 415-206-5532 for a phone screening
Conditions Studied
Interventions
- OTHER Dietary intervention (calorie restricted diet)
Study Locations (1)
California
- Touro University - Vallejo
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 41 participants |
| Start Date | 2007-09 |
| Est. Completion | 2012-10-12 |
| Phase | NA |
What the finished NCT00714129 record still lists
NCT00714129 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 41 participants, a relatively small participant target, below the 3,028-participant average among 338 other Diabetes trials with a reported enrollment target (99% lower).
The record links to 2 conditions, with Diabetes appearing as the primary indexed condition, and to 1 intervention - of which Dietary intervention (calorie restricted diet) is the first listed.
NCT00714129 reports a single indexed study location in California.
Frequently Asked Questions
What is clinical trial NCT00714129 about?
NCT00714129 is a clinical study titled "De Novo Lipogenesis, Lipid and Carbohydrate Metabolism in Non-alcoholic Fatty Liver Disease". The worldwide epidemic of obesity is paralleled with increased cases of non-alcoholic liver disease (liver fat accumulation) and diabetes. Fat belongs in the adipose tissue, and if excess fat accumulates in the liver or muscle, these tissues cannot use sugar efficiently. It has been discovered that ...
What is the current status of trial NCT00714129?
This trial is currently completed. It is a NA study. The enrollment target is 41 participants. The study started on 2007-09. Estimated completion is 2012-10-12.
What conditions does trial NCT00714129 study?
This clinical trial studies the following conditions: Diabetes, Non-alcoholic Fatty Liver Disease.
What interventions are being tested in trial NCT00714129?
The interventions under investigation include: Dietary intervention (calorie restricted diet) (OTHER).
Who is sponsoring clinical trial NCT00714129?
This trial is sponsored by University of California, San Francisco, which has 1,713 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT00714129 being conducted?
This trial has 1 study location across California. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
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Where NCT00714129's enrollment target sits among peer trials
41 262nd of 338 higher than 77 of 338 other Diabetes trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Diabetes trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
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