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ClinicalTrials.gov 6 recruiting now early-phase tilt small index

Motivation: early-phase trial registry

6 of 14 indexed Motivation trials are currently recruiting, with more weight in Phase 1-2.

Corpus placement: #1,230 of 28,707 conditions by registered trial count.

14 US clinical trials · 6 currently recruiting · #1,230 of 28,707 conditions by registered trial count

Motivation: 14 US clinical trials tracked, 6 recruiting.

Motivation is the subject of 14 registered US clinical trials on ClinicalTrials.gov, 6 of them currently open to new participants. 1 are in Phase 3-4 (later-stage) and 2 in Phase 1-2 (earlier-stage). The most active sponsor is Medical University of South Carolina, running 2 of these trials.

Enrollment posture brief

Registry condition motivation

OPEN 6 | RECR 43% | LATE 1 | EARLY 2 | RANK #1230 | SPON 2

Nearest open-share peer: Acute Myelogenous Leukemia (AML) (43% recruiting · 7 trials)

Motivation (this)43%Acute Respiratory Failure35.7%Adherence, Medication35.7%Acromegaly28.6%Abscess7.1%
Open-enrollment share among volume-matched conditions near Motivation

Motivation lists 6 open slots (43% of 14 indexed trials). Peers are matched on registered volume, not therapeutic-area browse lists. How peer matching works →

Key findings

What ClinicalTrials.gov does not surface for Motivation on its own pages , computed from the registry mirror as of 2026-08-08. Each line carries its own denominator so it can be quoted as it stands.

  1. Motivation is recruiting below its size-band peers.

    6 of 14 indexed trials (42.9%) are open to enrollment, against a 46.5% average across 27,806 conditions with fewer than 20 trials. The peer set uses the same ClinicalTrials.gov-derived counts as this page.

  2. Sponsorship of Motivation trials is spread across many organizations.

    Medical University of South Carolina accounts for 2 of 14 trials (14.3%). 13 distinct sponsors appear on at least one study for this condition label.

  3. Typical Motivation enrolment sits around 80 participants.

    Median target enrolment is 80 among the 14 trials that report a genuine target (sentinel values excluded). 8 of those (57.1%) plan for fewer than 100 participants.

  4. Motivation research is mostly interventional.

    13 interventional and 1 observational studies make up this index (92.9% interventional). Study type is sponsor-reported on ClinicalTrials.gov.

Phase 12Phase 41

Open and recent trials

14 total, page 1 of 1

RECRUITING NA 190 participants

MRI Neurofeedback and Brain Circuits Related to Motivation in Healthy Participants

Duke University

NCT05929898

RECRUITING NA 180 participants

Motivation for Daily Living Skills

Children's Hospital of Philadelphia

NCT07159308

RECRUITING NA 80 participants

InformationSeekingMesolimbicEngagementStudy2

Temple University

NCT06257433

RECRUITING NA 70 participants

Understanding Motivation in Parkinson's Patients Through Neurophysiology

University of California, San Francisco

NCT05065151

RECRUITING NA 40 participants

Glucose and Motivation States

University of South Florida

NCT07255183

RECRUITING Phase 1 40 participants

Accelerated rTMS vs. Sham for Stroke Apathy

Medical University of South Carolina

NCT07113067

COMPLETED Phase 4 517 participants

Identifying Treatments to Motivate Smokers to Quit

University of Wisconsin, Madison

NCT01122238

COMPLETED NA 309 participants

Community-based Intervention Effects on Older Adults' Physical Activity

University of Minnesota

NCT03326141

COMPLETED NA 182 participants

Accelerometer-linked Online Intervention to Promote Physical Activity in Adolescents

HopeLab Foundation

NCT02425384

COMPLETED NA 140 participants

Efficacy of the Tony Robbins Rapid Planning Method (RPM)

Applied Science & Performance Institute

NCT06539949

COMPLETED NA 36 participants

Stroke and CPAP Outcome Study 3

University of Washington

NCT06029959

COMPLETED 30 participants

Responses to Physical Activity Messages Among Midlife Adults

Rowan University

NCT04711512

COMPLETED Phase 1 14 participants

Accelerated rTMS for Post-Stroke Apathy

Medical University of South Carolina

NCT05878457

COMPLETED NA 14 participants

ARCH II Study (Alcohol Research Center on HIV Study II)

University of Florida

NCT02563574

Phase Distribution

PhaseTrial count
Phase 1 2
Phase 4 1

Named interventions

Most-linked intervention names on Motivation records (sponsor-reported on ClinicalTrials.gov). Counts are trial links, not unique products.

Motivational Interviewing Behavioral
2 trials
Neurocognitive assessments Other
1 trials
Questionnaire assessment Other
1 trials
Information about Health and Wellness Other
1 trials
Intrapersonal Behavior Change Strategies Behavioral
1 trials
Interpersonal Behavior Change Strategies Behavioral
1 trials
Physical activity monitors (e.g., Fitbit) Device
1 trials
Mobile Health intervention Behavioral
1 trials

US sites by state

Facility locations filed on Motivation trials. A trial with sites in several states counts in each.

Florida 3 trials
South Carolina 2 trials
Pennsylvania 2 trials
California 2 trials
West Virginia 1 trials
Wisconsin 1 trials
Washington 1 trials
New Jersey 1 trials

Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.

What to do with this Motivation page

14 registered trials, 6 currently recruiting, is a starting point for a conversation, not a diagnosis or a recommendation.

Trial and recruiting counts reflect ClinicalTrials.gov registry status as of the data vintage above; individual trial eligibility and enrollment status can change.

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This Motivation condition card totals 14 registered trials; most-linked intervention Motivational Interviewing; top US site state Florida. See our editorial standards & corrections policy, the methodology behind these numbers, the data changelog, or report a data error.