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ClinicalTrials.gov 14 recruiting now early-phase tilt

Metastatic Prostate Carcinoma: early-phase trial registry

14 of 38 indexed Metastatic Prostate Carcinoma trials are currently recruiting, with more weight in Phase 1-2.

Corpus placement: #393 of 28,707 conditions by registered trial count.

38 US clinical trials · 14 currently recruiting · #393 of 28,707 conditions by registered trial count

Metastatic Prostate Carcinoma: 38 US clinical trials tracked, 14 recruiting.

Metastatic Prostate Carcinoma is the subject of 38 registered US clinical trials on ClinicalTrials.gov, 14 of them currently open to new participants. 2 are in Phase 3-4 (later-stage) and 29 in Phase 1-2 (earlier-stage). The most active sponsor is M.D. Anderson Cancer Center, running 6 of these trials.

Enrollment posture brief

Registry condition metastatic-prostate-carcinoma

OPEN 14 | RECR 37% | LATE 2 | EARLY 29 | RANK #393 | SPON 6

Nearest open-share peer: Alcohol Consumption (37% recruiting · 19 trials)

Acute Leukemia55.3%Eating Disorders47.4%Food Insecurity44.7%Metastatic Prostate Carc (th…37%Back Pain31.6%
Open-enrollment share among volume-matched conditions near Metastatic Prostate Carcinoma

Metastatic Prostate Carcinoma lists 14 open slots (37% of 38 indexed trials). Peers are matched on registered volume, not therapeutic-area browse lists. How peer matching works →

Key findings

What ClinicalTrials.gov does not surface for Metastatic Prostate Carcinoma on its own pages , computed from the registry mirror as of 2026-08-08. Each line carries its own denominator so it can be quoted as it stands.

  1. Metastatic Prostate Carcinoma is recruiting below its size-band peers.

    14 of 38 indexed trials (36.8%) are open to enrollment, against a 39.7% average across 762 conditions with 20-99 trials. The peer set uses the same ClinicalTrials.gov-derived counts as this page.

  2. One sponsor concentrates Metastatic Prostate Carcinoma research.

    M.D. Anderson Cancer Center accounts for 6 of 38 trials (15.8%). 19 distinct sponsors appear on at least one study for this condition label.

  3. Most Metastatic Prostate Carcinoma trials plan to enrol fewer than 100 people.

    Median target enrolment is 60 among the 38 trials that report a genuine target (sentinel values excluded). 27 of those (71.1%) plan for fewer than 100 participants.

  4. Metastatic Prostate Carcinoma research is mostly interventional.

    35 interventional and 3 observational studies make up this index (92.1% interventional). Study type is sponsor-reported on ClinicalTrials.gov.

Phase 19Phase 220Phase 31Phase 41

Open and recent trials

38 total, page 1 of 1

RECRUITING Phase 3 804 participants

Treating Prostate Cancer That Has Come Back After Surgery With Apalutamide and Targeted Radiation Based on PET Imaging

ECOG-ACRIN Cancer Research Group

NCT04423211

RECRUITING NA 800 participants

Access to Genetic Testing in Underserved Patients With Cancer

University of Southern California

NCT06422455

RECRUITING Early Phase 1 220 participants

Immunological Effects of Vitamin D Replacement Among Black/African American Prostate Cancer Patients

Mayo Clinic

NCT05045066

RECRUITING Phase 2 210 participants

Bright White Light Therapy in Reducing Cancer-Related Fatigue and Depression in Advanced Prostate Cancer Patients Undergoing Treatment With ADT Combination Therapy

City of Hope Medical Center

NCT05869682

RECRUITING Phase 2 125 participants

FDG-PET-Guided Metastasis Directed Radiation Therapy for the Treatment of Metastatic Hormone Sensitive Prostate Cancer, The PRTY Trial

Northwestern University

NCT06244004

RECRUITING NA 120 participants

Peer Navigation for the Support of Metastatic Prostate Cancer Patients Undergoing Genetic Evaluation

Thomas Jefferson University

NCT05487846

RECRUITING NA 80 participants

Debunking the Frailty-sarcopenIa-ADT Axis in mEtastatic Prostate canceR With multiComponent Exercise: The FIERCE Trial

Dana-Farber Cancer Institute

NCT06040125

RECRUITING 48 participants

Impact of DNA Repair Pathway Alterations on Sensitivity to Radium-223 in Bone Metastatic Castration-resistant Prostate Cancer

University of Washington

NCT04489719

RECRUITING NA 40 participants

Cryoablation Combined With Stereotactic Body Radiation Therapy for the Treatment of Painful Bone Metastases, the CROME Trial

M.D. Anderson Cancer Center

NCT04693377

RECRUITING Phase 2 38 participants

Evaluating In Home Cancer Therapy Versus In Clinic Cancer Therapy in Black Men With Locally Advanced, Biochemically Recurrent and Metastatic Prostate Cancer

Mayo Clinic

NCT07073794

RECRUITING Phase 1 30 participants

Image-Guided Biopsies to Identify Mechanisms of Resistance in Patients With Metastatic Castration Resistant Prostate Cancer Treated With 177Lu-PSMA Radioligand Therapy

Jonsson Comprehensive Cancer Center

NCT05398302

RECRUITING 30 participants

Extending Prostate Genetic Awareness, Navigation, and Delivery: The EXPAND Network

Thomas Jefferson University

NCT05627219

RECRUITING Phase 1 21 participants

PSCA-Targeting CAR-T Cells Plus or Minus Radiation for the Treatment of Patients With PSCA+ Metastatic Castration-Resistant Prostate Cancer

City of Hope Medical Center

NCT05805371

RECRUITING Phase 1 14 participants

Bipolar Androgen Therapy to Restore Sensitivity to Androgen Deprivation Therapy for Patients With Metastatic Castration Resistant Prostate Cancer

Roswell Park Cancer Institute

NCT06305598

ACTIVE NOT RECRUITING Phase 2 196 participants

Abiraterone Acetate, Prednisone, and Apalutamide With or Without Ipilimumab or Cabazitaxel and Carboplatin in Treating Patients With Metastatic Castration-Resistant Prostate Cancer

M.D. Anderson Cancer Center

NCT02703623

ACTIVE NOT RECRUITING Phase 1 173 participants

Avelumab, Utomilumab, Anti-OX40 Antibody PF-04518600, and Radiation Therapy in Treating Patients With Advanced Malignancies

M.D. Anderson Cancer Center

NCT03217747

ACTIVE NOT RECRUITING Phase 2 120 participants

Cabazitaxel, Carboplatin, and Cetrelimab Followed by Niraparib With or Without Cetrelimab for the Treatment of Aggressive Variant Metastatic Prostate Cancer

M.D. Anderson Cancer Center

NCT04592237

ACTIVE NOT RECRUITING Phase 4 100 participants

Cognitive Effects of Androgen Receptor Directed Therapies for Advanced Prostate Cancer

Northwestern University

NCT03016741

ACTIVE NOT RECRUITING 92 participants

Gene Expression in Patients With Metastatic Prostate Cancer Receiving CYP-17 Inhibition Therapy

Mayo Clinic

NCT01953640

ACTIVE NOT RECRUITING Phase 2 90 participants

Testing Two Oral Drugs Combination (Cediranib and Olaparib) Compared to a Single Drug (Olaparib) for Men With Advanced Prostate Cancer

National Cancer Institute (NCI)

NCT02893917

ACTIVE NOT RECRUITING Phase 2 79 participants

Testing Interruption of Hormonal Medications in Patients Responding Exceptionally to Therapy for Metastatic Prostate Cancer, (A-DREAM)

Alliance for Clinical Trials in Oncology

NCT05241860

ACTIVE NOT RECRUITING Phase 2 73 participants

M6620 and Carboplatin With or Without Docetaxel in Treating Patients With Metastatic Castration-Resistant Prostate Cancer

National Cancer Institute (NCI)

NCT03517969

ACTIVE NOT RECRUITING Phase 2 70 participants

Abiraterone/Prednisone, Olaparib, or Abiraterone/Prednisone + Olaparib in Patients With Metastatic Castration-Resistant Prostate Cancer With DNA Repair Defects

Northwestern University

NCT03012321

ACTIVE NOT RECRUITING Phase 1 65 participants

DS3201 and Ipilimumab for the Treatment of Metastatic Prostate, Urothelial and Renal Cell Cancers

M.D. Anderson Cancer Center

NCT04388852

ACTIVE NOT RECRUITING Phase 2 60 participants

Abiraterone Acetate, Prednisone, and Apalutamide in Treating Patients With Hormone-Naive Metastatic Prostate Cancer

M.D. Anderson Cancer Center

NCT03821792

ACTIVE NOT RECRUITING Phase 1 37 participants

Enzalutamide and Cabazitaxel in Treating Patients With Metastatic, Castration-Resistant Prostate Cancer

OHSU Knight Cancer Institute

NCT02522715

ACTIVE NOT RECRUITING Phase 2 37 participants

Abiraterone Acetate, Niclosamide, and Prednisone in Treating Patients With Hormone-Resistant Prostate Cancer

Mamta Parikh

NCT02807805

ACTIVE NOT RECRUITING Phase 2 15 participants

68Ga-PSMA-11 PET for the Diagnosis of Metastatic Castration Resistant Prostate Cancer

Thomas Hope

NCT04716725

ACTIVE NOT RECRUITING Phase 2 14 participants

Trametinib in Treating Patients With Progressive Metastatic Hormone-Resistant Prostate Cancer

Jonsson Comprehensive Cancer Center

NCT02881242

ACTIVE NOT RECRUITING Phase 1 14 participants

PSCA-CAR T Cells in Treating Patients With PSCA+ Metastatic Castration Resistant Prostate Cancer

City of Hope Medical Center

NCT03873805

ACTIVE NOT RECRUITING Phase 2 7 participants

Advanced ChemoHormonal Therapy for Treatment Naive Metastatic Prostate Cancer

OHSU Knight Cancer Institute

NCT04267887

COMPLETED Phase 2 937 participants

68GA-PSMA-11 PET/CT Scan in Impacting Treatment Strategies for Patients With Prostate Cancer

Jonsson Comprehensive Cancer Center

NCT04050215

COMPLETED Phase 2 54 participants

CYT107 After Vaccine Treatment (Provenge®) in Patients With Metastatic Castration-Resistant Prostate Cancer

Fred Hutchinson Cancer Center

NCT01881867

COMPLETED Phase 2 32 participants

Abiraterone Acetate in Treating Patients With Metastatic Hormone-Resistant Prostate Cancer

University of Washington

NCT01503229

COMPLETED Phase 1 26 participants

Cytoreductive Prostatectomy in Treating Patients With Newly Diagnosed, Metastatic Prostate Cancer

Rutgers, The State University of New Jersey

NCT02458716

COMPLETED Phase 2 17 participants

Gallium Ga 68-DOTATATE PET/CT in Diagnosing Patients With Metastatic Castration Resistant Prostate Cancer

Emory University

NCT03448458

COMPLETED Phase 2 14 participants

Docetaxel and Carboplatin in Treating Patients With Metastatic, Castration Resistant Prostate Cancer Containing Inactivated Genes in the BRCA 1/2 Pathway

University of Washington

NCT02598895

COMPLETED Phase 2 2 participants

Sipuleucel-T With or Without Tasquinimod in Treating Patients With Metastatic Hormone-Resistant Prostate Cancer

Roswell Park Cancer Institute

NCT02159950

Phase Distribution

PhaseTrial count
Phase 1 9
Phase 2 20
Phase 3 1
Phase 4 1

Named interventions

Most-linked intervention names on Metastatic Prostate Carcinoma records (sponsor-reported on ClinicalTrials.gov). Counts are trial links, not unique products.

Laboratory Biomarker Analysis Other
9 trials
Abiraterone Acetate Drug
7 trials
Prednisone Drug
7 trials
Quality-of-Life Assessment Other
7 trials
Computed Tomography Procedure
6 trials
Questionnaire Administration Other
5 trials
Apalutamide Drug
4 trials
Carboplatin Drug
4 trials

US sites by state

Facility locations filed on Metastatic Prostate Carcinoma trials. A trial with sites in several states counts in each.

California 17 trials
Texas 6 trials
Washington 5 trials
New York 5 trials
Florida 5 trials
Pennsylvania 4 trials
Massachusetts 4 trials
Illinois 4 trials

Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.

What to do with this Metastatic Prostate Carcinoma page

38 registered trials, 14 currently recruiting, is a starting point for a conversation, not a diagnosis or a recommendation.

Trial and recruiting counts reflect ClinicalTrials.gov registry status as of the data vintage above; individual trial eligibility and enrollment status can change.

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This Metastatic Prostate Carcinoma condition card totals 38 registered trials; most-linked intervention Laboratory Biomarker Analysis; top US site state California. See our editorial standards & corrections policy, the methodology behind these numbers, the data changelog, or report a data error.