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ClinicalTrials.gov 14 recruiting now early-phase tilt

Metastatic Pancreatic Cancer: early-phase trial registry

14 of 33 indexed Metastatic Pancreatic Cancer trials are currently recruiting, with more weight in Phase 1-2.

Corpus placement: #463 of 28,707 conditions by registered trial count.

33 US clinical trials · 14 currently recruiting · #463 of 28,707 conditions by registered trial count

Metastatic Pancreatic Cancer: 33 US clinical trials tracked, 14 recruiting.

Metastatic Pancreatic Cancer is the subject of 33 registered US clinical trials on ClinicalTrials.gov, 14 of them currently open to new participants. 2 are in Phase 3-4 (later-stage) and 27 in Phase 1-2 (earlier-stage). The most active sponsor is Fox Chase Cancer Center, running 2 of these trials.

Enrollment posture brief

Registry condition metastatic-pancreatic-cancer

OPEN 14 | RECR 42% | LATE 2 | EARLY 27 | RANK #463 | SPON 2

Nearest open-share peer: Idiopathic Pulmonary Fibrosis (42% recruiting · 52 trials)

Barrett Esophagus54.5%Clinical Stage IV Cutaneous 45.5%Metastatic Pancreatic Ca (th…42%Child Development39.4%Anatomic Stage IIB Breast Ca24.2%
Open-enrollment share among volume-matched conditions near Metastatic Pancreatic Cancer

Metastatic Pancreatic Cancer lists 14 open slots (42% of 33 indexed trials). Peers are matched on registered volume, not therapeutic-area browse lists. How peer matching works →

Key findings

What ClinicalTrials.gov does not surface for Metastatic Pancreatic Cancer on its own pages , computed from the registry mirror as of 2026-08-08. Each line carries its own denominator so it can be quoted as it stands.

  1. Metastatic Pancreatic Cancer is recruiting above its size-band peers.

    14 of 33 indexed trials (42.4%) are open to enrollment, against a 39.7% average across 762 conditions with 20-99 trials. The peer set uses the same ClinicalTrials.gov-derived counts as this page.

  2. Sponsorship of Metastatic Pancreatic Cancer trials is spread across many organizations.

    Fox Chase Cancer Center accounts for 2 of 33 trials (6.1%). 26 distinct sponsors appear on at least one study for this condition label.

  3. Most Metastatic Pancreatic Cancer trials plan to enrol fewer than 100 people.

    Median target enrolment is 30 among the 33 trials that report a genuine target (sentinel values excluded). 25 of those (75.8%) plan for fewer than 100 participants.

  4. Metastatic Pancreatic Cancer research is mostly interventional.

    32 interventional and 1 observational studies make up this index (97% interventional). Study type is sponsor-reported on ClinicalTrials.gov.

Phase 110Phase 217Phase 32

Open and recent trials

33 total, page 1 of 1

RECRUITING Phase 3 614 participants

A Study to Evaluate the Effectiveness and Safety of Setidegrasib, Given With Either mFOLFIRINOX or NALIRIFOX Chemotherapies, in People With Pancreatic Cancer

Astellas Pharma Global Development

NCT07409272

RECRUITING Phase 3 480 participants

The Effect of Kinisoquin™ on Thromboembolic Events in Patients With Metastatic or Locally Advanced Pancreatic Cancer

Quercis Pharma

NCT06861088

RECRUITING Phase 2 332 participants

Immunotherapy Using Tumor Infiltrating Lymphocytes for Patients With Metastatic Cancer

National Cancer Institute (NCI)

NCT01174121

RECRUITING Phase 1 116 participants

Metarrestin (ML-246) in Subjects With Metastatic Solid Tumors

National Cancer Institute (NCI)

NCT04222413

RECRUITING Phase 1 104 participants

Basal-like PDAC Treated With Gemcitabine, Erlotinib, and Nab-paclitaxel

UNC Lineberger Comprehensive Cancer Center

NCT06483555

RECRUITING Phase 2 89 participants

Ceralasertib (AZD6738) Alone and in Combination With Olaparib or Durvalumab in Patients With Solid Tumors

Rahul Aggarwal

NCT03682289

RECRUITING Phase 1 71 participants

A Study of Evofosfamide in Combination with Zalifrelimab and Balstilimab

ImmunoGenesis

NCT06782555

RECRUITING Phase 1 40 participants

Nab-Paclitaxel + Cisplatin + Gemcitabine + TTF in pt. w/ Metastatic PAC

Mayo Clinic

NCT04605913

RECRUITING Phase 2 38 participants

Multi-agent Low Dose Chemotherapy GAX-CI Followed by Olaparib and Pembro in Metastatic Pancreatic Ductal Cancer.

Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins

NCT04753879

RECRUITING NA 30 participants

Alpha Radiation Emitters Device for the Treatment of Pancreatic Cancer With Chemotherapy for the Treatment of Locally Advanced and Metastatic Pancreatic Cancer

Alpha Tau Medical

NCT06698458

RECRUITING Phase 1 30 participants

Study of Effect of Azeliragon in Patients Refractory to Prior Treatment of Metastatic Pancreatic Cancer

Cantex Pharmaceuticals

NCT05766748

RECRUITING Early Phase 1 30 participants

First-in-human Study of the Theranostic Pair [68Ga]Ga DOTA-5G and [177Lu]Lu DOTA-ABM-5G in Pancreatic Cancer

University of California, Davis

NCT04665947

RECRUITING Phase 1 24 participants

SHARON: A Clinical Trial for Metastatic Cancer Using Chemotherapy and Patients' Own Stem Cells

General Oncology

NCT04150042

RECRUITING Phase 2 20 participants

The Miami "EMPIRE" Trial - Eradication of Metastatic Pancreatic Cancer With Immuno-Radiation

Benjamin Spieler

NCT06843551

ACTIVE NOT RECRUITING Phase 2 393 participants

A Study of Zolbetuximab (IMAB362) in Adults With Pancreatic Cancer

Astellas Pharma Global Development

NCT03816163

ACTIVE NOT RECRUITING Phase 2 37 participants

Redefining FOLFIORINOX in Older Pancreatic Cancer Patients

Fox Chase Cancer Center

NCT05360732

ACTIVE NOT RECRUITING Phase 2 30 participants

Proglumide and Chemotherapy for Metastatic Pancreatic Cancer

Georgetown University

NCT05827055

ACTIVE NOT RECRUITING Phase 2 30 participants

Nivolumab + Ipilimumab + Radiation in MSS Pancreatic Cancer

Massachusetts General Hospital

NCT04361162

ACTIVE NOT RECRUITING Phase 2 30 participants

Modified FOLFIRINOX Alternated With Biweekly Gemcitabine Plus Nab-Paclitaxel Untreated Pancreatic Cancer

Lyudmyla Berim

NCT04672005

ACTIVE NOT RECRUITING Phase 2 30 participants

Atezolizumab + Cabozantinib in Patients w/ Metastatic, Refractory Pancreatic Cancer

University of Arizona

NCT04820179

ACTIVE NOT RECRUITING Phase 2 29 participants

A Study of Glipizide to Treat High Blood Sugar in People With Pancreatic Cancer

Memorial Sloan Kettering Cancer Center

NCT06168812

ACTIVE NOT RECRUITING Phase 2 28 participants

Study of Combined SGT-53 Plus Gemcitabine/Nab-Paclitaxel for Metastatic Pancreatic Cancer

SynerGene Therapeutics

NCT02340117

ACTIVE NOT RECRUITING 24 participants

Early Treatment ctDNA Dynamics to Predict Response to Chemotherapy

Northwell Health

NCT07122466

ACTIVE NOT RECRUITING Phase 1 17 participants

Pancrelipase in People With Pancreatic Ductal Adenocarcinoma (PDAC)

Memorial Sloan Kettering Cancer Center

NCT05642962

COMPLETED Phase 2 279 participants

PEGPH20 Plus Nab-Paclitaxel Plus Gemcitabine Compared With Nab-Paclitaxel Plus Gemcitabine in Participants With Stage IV Untreated Pancreatic Cancer

Halozyme Therapeutics

NCT01839487

COMPLETED NA 216 participants

Improving Informed Consent for Palliative Chemotherapy

Dana-Farber Cancer Institute

NCT02282722

COMPLETED Phase 2 75 participants

Study of Modified FOLFIRINOX in Advanced Pancreatic Cancer

Yale University

NCT01523457

COMPLETED Phase 2 58 participants

A Phase II, Trial of Ixabepilone Plus Cetuximab as First Line Therapy for Metastatic Pancreatic Cancer

R-Pharm

NCT00383149

COMPLETED Phase 2 50 participants

BrUOG 292: FOLFOX-A For Metastatic Pancreatic Cancer: A Phase II Brown University Oncology Research Group Trial

Brown University

NCT02080221

COMPLETED Phase 1 27 participants

Study of Low-Dose Fractionated Radiotherapy in Patients With Locally Advanced Metastatic Pancreatic Cancer

Fox Chase Cancer Center

NCT00761345

COMPLETED Phase 1 27 participants

A Trial of GW572016, Gemcitabine and Oxaliplatin for Metastatic Pancreaticobiliary Cancer Schema

Brown University

NCT00439179

COMPLETED Phase 2 18 participants

Niraparib + Dostarlimab + RT in Pancreatic Cancer

Massachusetts General Hospital

NCT04409002

COMPLETED NA 10 participants

EL CENTRO: Engaging Latinos in the Center of Cancer Treatment Options

Dana-Farber Cancer Institute

NCT03602885

Phase Distribution

PhaseTrial count
Phase 1 10
Phase 2 17
Phase 3 2

Named interventions

Most-linked intervention names on Metastatic Pancreatic Cancer records (sponsor-reported on ClinicalTrials.gov). Counts are trial links, not unique products.

Gemcitabine Drug
5 trials
Folfirinox Drug
2 trials
Erlotinib Drug
2 trials
gemcitabine Drug
2 trials
Nab paclitaxel Drug
2 trials
Balstilimab Drug
2 trials
Nab-paclitaxel Drug
2 trials
nab-paclitaxel Drug
2 trials

US sites by state

Facility locations filed on Metastatic Pancreatic Cancer trials. A trial with sites in several states counts in each.

Florida 10 trials
California 8 trials
New York 7 trials
Massachusetts 7 trials
Texas 5 trials
New Jersey 4 trials
Pennsylvania 3 trials
North Carolina 3 trials

Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.

What to do with this Metastatic Pancreatic Cancer page

33 registered trials, 14 currently recruiting, is a starting point for a conversation, not a diagnosis or a recommendation.

  • 14 Metastatic Pancreatic Cancer trials are currently recruiting, check eligibility criteria before contacting a site. Browse recruiting trials
  • Fox Chase Cancer Center sponsors the most Metastatic Pancreatic Cancer trials on record, review their full trial history before evaluating a specific study. See Fox Chase Cancer Center's trials
  • Bring the specific trial ID (NCT number) to your own doctor before enrolling, this page is a directory, not medical guidance. Read the trial-finding guide

Trial and recruiting counts reflect ClinicalTrials.gov registry status as of the data vintage above; individual trial eligibility and enrollment status can change.

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This Metastatic Pancreatic Cancer condition card totals 33 registered trials; most-linked intervention Gemcitabine; top US site state Florida. See our editorial standards & corrections policy, the methodology behind these numbers, the data changelog, or report a data error.