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ClinicalTrials.gov 7 recruiting now early-phase tilt small index

Metastatic Lung Cancer: early-phase trial registry

7 of 11 indexed Metastatic Lung Cancer trials are currently recruiting, with more weight in Phase 1-2.

Corpus placement: #1,577 of 28,707 conditions by registered trial count.

11 US clinical trials · 7 currently recruiting · #1,577 of 28,707 conditions by registered trial count

Metastatic Lung Cancer: 11 US clinical trials tracked, 7 recruiting.

Metastatic Lung Cancer is the subject of 11 registered US clinical trials on ClinicalTrials.gov, 7 of them currently open to new participants. 1 are in Phase 3-4 (later-stage) and 8 in Phase 1-2 (earlier-stage). The most active sponsor is TheRas, Inc., d/b/a BBOT (BridgeBio Oncology Therapeutics), running 2 of these trials.

Enrollment posture brief

Registry condition metastatic-lung-cancer

OPEN 7 | RECR 64% | LATE 1 | EARLY 8 | RANK #1577 | SPON 2

Nearest open-share peer: Advanced Melanoma (64% recruiting · 22 trials)

Acute Pancreatitis81.8%Metastatic Lung Cancer (this)64%Acute Stroke45.5%Acquired Brain Injury36.4%Acute Lung Injury9.1%
Open-enrollment share among volume-matched conditions near Metastatic Lung Cancer

Metastatic Lung Cancer lists 7 open slots (64% of 11 indexed trials). Peers are matched on registered volume, not therapeutic-area browse lists. How peer matching works →

Key findings

What ClinicalTrials.gov does not surface for Metastatic Lung Cancer on its own pages , computed from the registry mirror as of 2026-08-08. Each line carries its own denominator so it can be quoted as it stands.

  1. Metastatic Lung Cancer is recruiting above its size-band peers.

    7 of 11 indexed trials (63.6%) are open to enrollment, against a 46.5% average across 27,806 conditions with fewer than 20 trials. The peer set uses the same ClinicalTrials.gov-derived counts as this page.

  2. One sponsor concentrates Metastatic Lung Cancer research.

    TheRas, Inc., d/b/a BBOT (BridgeBio Oncology Therapeutics) accounts for 2 of 11 trials (18.2%). 10 distinct sponsors appear on at least one study for this condition label.

  3. Typical Metastatic Lung Cancer enrolment sits around 90 participants.

    Median target enrolment is 90 among the 11 trials that report a genuine target (sentinel values excluded). 6 of those (54.5%) plan for fewer than 100 participants.

  4. Metastatic Lung Cancer research is mostly interventional.

    10 interventional and 1 observational studies make up this index (90.9% interventional). Study type is sponsor-reported on ClinicalTrials.gov.

Phase 16Phase 22Phase 31

Open and recent trials

11 total, page 1 of 1

RECRUITING Phase 1 554 participants

Phase 1/2 Trial of S241656 in Selected RAS/MAPK Mutation- Positive Malignancies

Institut de Recherches Internationales Servier

NCT05786924

RECRUITING Phase 1 392 participants

Open-Label Study of BBO-10203 in Subjects With Advanced Solid Tumors

TheRas, Inc., d/b/a BBOT (BridgeBio Oncology Therapeutics)

NCT06625775

RECRUITING Phase 1 250 participants

Open-label Study of BBO-8520 in Adult Subjects With KRASG12C Non-small Cell Lung Cancer

TheRas, Inc., d/b/a BBOT (BridgeBio Oncology Therapeutics)

NCT06343402

RECRUITING NA 100 participants

Exercise as Maintenance Therapy in Advanced Lung Cancer

Indiana University

NCT06513663

RECRUITING Phase 2 90 participants

Combination Therapies With Adagrasib in Patients With Advanced NSCLC With KRAS G12C Mutation

Mirati Therapeutics

NCT05609578

RECRUITING Phase 1 52 participants

Safety and Efficacy of OBX-115 in Advanced Solid Tumors

Obsidian Therapeutics

NCT06060613

RECRUITING Phase 2 26 participants

Definitive Radiation for High-Risk Spine Metastases

Stony Brook University

NCT06165419

ACTIVE NOT RECRUITING Phase 1 200 participants

Phase 1/2 Study of Silevertinib (BDTX-1535) in Patients With Glioblastoma or Non-Small Cell Lung Cancer With EGFR Mutations

Black Diamond Therapeutics

NCT05256290

COMPLETED Phase 1 62 participants

Irradiation of Large Lung Tumors or Two or More Lung Metastases Simultaneously

The Netherlands Cancer Institute

NCT01543672

COMPLETED 24 participants

Immune Response Under Immunotherapy in Metastatic NSCLC: Sputum, Blood Samples and Microbioata Study

University Hospital, Tours

NCT04804137

COMPLETED Phase 3 5 participants

Immunotherapy With or Without SBRT in Patients With Stage IV Non-small Cell Lung Cancer

Wake Forest University Health Sciences

NCT03867175

Phase Distribution

PhaseTrial count
Phase 1 6
Phase 2 2
Phase 3 1

Named interventions

Most-linked intervention names on Metastatic Lung Cancer records (sponsor-reported on ClinicalTrials.gov). Counts are trial links, not unique products.

stool Other
1 trials
saliva Other
1 trials
sputum Other
1 trials
Blood Other
1 trials
silevertinib (BDTX-1535) monotherapy Drug
1 trials
FOLFOX6/FOLFOX7 Drug
1 trials
S241656 Drug
1 trials
Cisplatin/Carboplatin Combination
1 trials

US sites by state

Facility locations filed on Metastatic Lung Cancer trials. A trial with sites in several states counts in each.

New York 6 trials
California 6 trials
Texas 3 trials
Pennsylvania 3 trials
Missouri 3 trials
Michigan 3 trials
Massachusetts 3 trials
Florida 3 trials

Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.

What to do with this Metastatic Lung Cancer page

11 registered trials, 7 currently recruiting, is a starting point for a conversation, not a diagnosis or a recommendation.

Trial and recruiting counts reflect ClinicalTrials.gov registry status as of the data vintage above; individual trial eligibility and enrollment status can change.

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This Metastatic Lung Cancer condition card totals 11 registered trials; most-linked intervention stool; top US site state New York. See our editorial standards & corrections policy, the methodology behind these numbers, the data changelog, or report a data error.