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NCT04804137 · ClinicalTrials.gov registry record
Immune Response Under Immunotherapy in Metastatic NSCLC: Sputum, Blood Samples and Microbioata Study
A clinical trial of Metastatic Lung Cancer and Non-squamous Lung Cancer, sponsored by University Hospital, Tours.
- Completed
- Registry status
- 24
- Enrollment target
- 2
- Study locations
NCT04804137: Completed study of Metastatic Lung Cancer and Non-squamous Lung Cancer, sponsored by University Hospital, Tours.
NCT04804137 is a study of Metastatic Lung Cancer and Non-squamous Lung Cancer that has completed, run by University Hospital, Tours. The registered enrollment target is 24 participants, below the 173-participant average among 10 other Metastatic Lung Cancer trials with a reported enrollment target (86% lower). The trial reports 2 study locations across 2 states. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT04804137, a study of Metastatic Lung Cancer and Non-squamous Lung Cancer, has completed, sponsored by University Hospital, Tours.
- COMPLETED
- Registry status
- 24 participants
- Enrollment target
- 2
- Study locations
Study Summary
Prospective pathophysiological exploratory monocentric study, focusing on adult patients with non-small cell lung cancer (NSCLC) : non-squamous type without oncogenic addiction, metastatic, treated with immune checkpoint inhibitors alone or in combination with chemotherapy in front line at the CHRU de Tours, France.
Primary Outcome
* T cell sub populations assessed by their relative abundance, and will be expressed as a percentage of total T cells * B lymphocytes * Cytokine inflammatory profile: the level of activation/regulation, production of cytokines and cytotoxicity markers will be analysed as a percentage of cells expressing the markers or producing the cytokines in relation to the total cell population (e.g. HLA-DR+, CD38+, Bcl-2lo phenotype of CD8 T lymphocytes)
Conditions Studied
Interventions
- OTHER Blood
- OTHER sputum
- OTHER saliva
- OTHER stool
Study Locations (2)
California
- Ferreira Marion - Los Angeles
Other
- University hospital - Tours
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 24 participants |
| Start Date | 2021-05-03 |
| Est. Completion | 2023-07-31 |
What the finished NCT04804137 record still lists
NCT04804137 is an observational study that tracks outcomes without assigning an intervention. The registry caps enrollment at 24 participants, a relatively small participant target, below the 173-participant average among 10 other Metastatic Lung Cancer trials with a reported enrollment target (86% lower).
The record links to 2 conditions, with Metastatic Lung Cancer appearing as the primary indexed condition, and to 4 interventions - of which Blood is the first listed.
NCT04804137 reports a single indexed study location in California, Other.
Frequently Asked Questions
What is clinical trial NCT04804137 about?
NCT04804137 is a clinical study titled "Immune Response Under Immunotherapy in Metastatic NSCLC: Sputum, Blood Samples and Microbioata Study". Prospective pathophysiological exploratory monocentric study, focusing on adult patients with non-small cell lung cancer (NSCLC) : non-squamous type without oncogenic addiction, metastatic, treated with immune checkpoint inhibitors alone or in combination with chemotherapy in front line at the CHRU ...
What is the current status of trial NCT04804137?
This trial is currently completed. The enrollment target is 24 participants. The study started on 2021-05-03. Estimated completion is 2023-07-31.
What conditions does trial NCT04804137 study?
This clinical trial studies the following conditions: Metastatic Lung Cancer, Non-squamous Lung Cancer.
What interventions are being tested in trial NCT04804137?
The interventions under investigation include: Blood (OTHER), sputum (OTHER), saliva (OTHER), stool (OTHER).
Who is sponsoring clinical trial NCT04804137?
This trial is sponsored by University Hospital, Tours, which has 1 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT04804137 being conducted?
This trial has 2 study locations across California. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
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Where NCT04804137's enrollment target sits among peer trials
24 10th of 10 higher than 1 of 10 other Metastatic Lung Cancer trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Metastatic Lung Cancer trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
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