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ClinicalTrials.gov 34 recruiting now official registry

Mental Health clinical trials

34 of 63 indexed Mental Health trials are currently recruiting.

63 US clinical trials · 34 currently recruiting

Mental Health is the subject of 63 registered US clinical trials on ClinicalTrials.gov, 34 of them currently open to new participants. 1 are in Phase 3-4 (later-stage) and 1 in Phase 1-2 (earlier-stage). The most active sponsor is VA Office of Research and Development, running 4 of these trials.

The research picture

Mental Health has 63 registered US clinical trials, 34 of them open to new participants right now, about 54% of the total.

34
recruiting participants now
54%
of trials open to enrollment
1
in Phase 3–4 (later-stage)
4
top sponsor: VA Office of Research and Development
Phase 21Phase 41

Active & Recent Trials

63 total, page 1 of 2

RECRUITING 500,000 participants

Apple Health Study

Apple

NCT06958523

RECRUITING NA 5,000 participants

Life Skills Training for Soldiers Arriving at Their First Duty Location

Uniformed Services University of the Health Sciences

NCT07286955

RECRUITING NA 2,100 participants

Addressing the Mental Health and Emotional Well-being of Immigrants Through a Scalable Intervention

University of Texas at Austin

NCT06652711

RECRUITING NA 1,800 participants

The Happy Families Project: Testing the Effectiveness of a Conflict Resolution Program for Families

University of Notre Dame

NCT04980794

RECRUITING 1,500 participants

Resilience in Adolescent Development

University of Texas Southwestern Medical Center

NCT03458936

RECRUITING 1,500 participants

Colorado Community Engagement Alliance

University of Colorado, Denver

NCT07440316

RECRUITING NA 1,270 participants

SBIR/ STTR Family Check-up Online

University of Oregon

NCT06876246

RECRUITING NA 1,000 participants

First Face Training Evaluation in Tribal Communities

Cambridge Health Alliance

NCT05998005

RECRUITING NA 720 participants

Evaluation of the Parenting in the Moment Online Program for Forcibly Displaced Families

Arizona State University

NCT06548126

RECRUITING NA 700 participants

RCT for Latina Mental Health Using Web-Based Apps

University of California, Los Angeles

NCT06874790

RECRUITING 700 participants

Women s Health Awareness Community Resiliency, Environmental Action and Collaborations for Health (REACH) Equity

National Institute of Environmental Health Sciences (NIEHS)

NCT04983251

RECRUITING NA 640 participants

Effectiveness, Implementation, and Cost of Cognitive Processing Therapy in Prisons

University of Arkansas

NCT06923423

RECRUITING NA 500 participants

Does Social Media Impact Adolescent Mental Health?

Georgetown University

NCT06049888

RECRUITING NA 400 participants

Improving Alcohol and Substance Use Care Access, Outcome, Equity During the Reproductive Years

Emory University

NCT05910580

RECRUITING NA 400 participants

Project HOPEFUL: A PN-RCT With Implementation Science

University of Florida

NCT07475039

RECRUITING NA 400 participants

Trauma and Cardiometabolic Health in an American Indian Community

Montana State University

NCT06878885

RECRUITING NA 360 participants

Relationship Checkups to Reduce Veteran Suicide Risk

VA Office of Research and Development

NCT05525676

RECRUITING NA 350 participants

J-RISE: Relevant Implementation Strategies to Eliminate the Social and Structural Barriers to HIV Services Among Justice-involved Black Men Who Have Sex With Men and Other Key Populations

University of Chicago

NCT06477588

RECRUITING NA 254 participants

OurChild: A Health IT Solution to Reduce Minority Health Disparities

NYU Langone Health

NCT04677647

RECRUITING NA 230 participants

Doula Model of Care

University of Pennsylvania

NCT06915259

RECRUITING NA 200 participants

The SolanoConnex Trial: Evaluation of a Mental Health Access Project

Touro University, California

NCT07306013

RECRUITING NA 180 participants

Study of Mental Health and Relationships

University of Illinois at Chicago

NCT06534827

RECRUITING NA 150 participants

Resilience Through Interventions for Successful Early Outcomes

University of North Carolina, Chapel Hill

NCT06669624

RECRUITING NA 150 participants

Family Mental Health Family Navigator Project (FMHN)

University of California, San Francisco

NCT04822636

RECRUITING NA 140 participants

Health Without Barriers/Salud Sin Barreras- Northern Colorado

Colorado State University

NCT06822387

RECRUITING NA 120 participants

Mindfulness-Based Intervention With a Supplement for Stress-Related Problems in College Students Across Multiple Sites (4SITE)

Colorado State University

NCT07098845

RECRUITING NA 120 participants

Family Foundations for Special Education Trial

Penn State University

NCT07400497

RECRUITING NA 120 participants

Psychological Assessment of Scoliosis Patients Undergoing Surgical Management

Montefiore Medical Center

NCT05774002

RECRUITING NA 100 participants

Cracking Consciousness Study With Monroe & Neuphoria (Cohort 2&3)

Efforia

NCT07298369

RECRUITING NA 100 participants

Virtual Patient Groups for Sarcoidosis Associated Fatigue

The Cleveland Clinic

NCT07073963

RECRUITING NA 75 participants

Understanding the Role of Doulas in Supporting People With PMADs

University of Montana

NCT05763537

RECRUITING NA 40 participants

Transition Health and Resilience Through Valued Experiences (THRiVE) Pilot for Newly Separated Veterans

RTI International

NCT06778278

RECRUITING Phase 2 40 participants

Mindfulness-assisted Psychedelic Therapy

University of Southern California

NCT06233344

RECRUITING NA 32 participants

BASIS Optimization

University of Washington

NCT06672835

ACTIVE NOT RECRUITING NA 81,424 participants

Behavioral Health Interdisciplinary Program - Collaborative Chronic Care Model (BHIP-CCM) Enhancement Project 2.0

VA Office of Research and Development

NCT05997836

ACTIVE NOT RECRUITING NA 15,195 participants

Supportive Release Center Study

University of Chicago

NCT03616990

ACTIVE NOT RECRUITING NA 4,000 participants

Evaluating the Impacts of a Well-Being Mobile App in Mexico

University of Texas at Austin

NCT07109648

ACTIVE NOT RECRUITING NA 600 participants

Mixed Methods Evaluation of the Pomona Household Universal Grant (HUG) Program

University of California, Los Angeles

NCT06505811

ACTIVE NOT RECRUITING NA 150 participants

Viome Nutritional Programs to Improve Clinical Outcomes for Mental Health Conditions

Viome

NCT05563857

ACTIVE NOT RECRUITING NA 124 participants

RISE for Nurse Preceptors

AdventHealth

NCT06822777

ACTIVE NOT RECRUITING NA 85 participants

Medical-legal Partnerships to Prevent Evictions and Homelessness Among Veterans

VA Office of Research and Development

NCT04924088

ACTIVE NOT RECRUITING NA 76 participants

Novel Methods for Implementing Measurement-Based Care for Youth in Low-resource Environments

Kaiser Permanente

NCT05644756

COMPLETED NA 1,044 participants

Building Infrastructure for Community Capacity in Accelerating Integrated Care

Massachusetts General Hospital

NCT04092777

COMPLETED NA 1,000 participants

Systems Aligning for Equity (SAFE) Spaces

New York University

NCT05658068

COMPLETED NA 950 participants

Evaluation of the "Americans in Motion - Healthy Interventions" Project

American Academy of Family Physicians

NCT00534482

COMPLETED NA 943 participants

Integrating Clinical Practice Guidelines for Smoking Cessation Into Mental Health Care for Veterans With Posttraumatic Stress Disorder

US Department of Veterans Affairs

NCT00118534

COMPLETED 917 participants

International Kink Health Study

The Alternative Sexualities Health Research Alliance

NCT05318053

COMPLETED 886 participants

Seguimos Avanzando - Latino Youth Coping With Discrimination

Massachusetts General Hospital

NCT04875208

COMPLETED NA 671 participants

The BE WITH Project: A Partially Nested Randomized Control Trial (PN-RCT)

University of Florida

NCT07204444

COMPLETED 628 participants

Evaluation of Enrollment, Dynamics of Care and Patient Outcomes in the NYS Medicaid HIV Special Needs Plans

Memorial Sloan Kettering Cancer Center

NCT00577811

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Phase Distribution

PhaseTrial count
Phase 2 1
Phase 4 1

Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.

Reading the Mental Health Trial Landscape

63 indexed Mental Health studies · 34 recruiting (54%).

Phase mix: 1 late (III/IV) vs 1 early (I/II).

Top sponsor: VA Office of Research and Development (4 trials), 9 others listed. 50 shown below, recruiting first.

How to read this condition's trial landscape

That ratio is a useful proxy for activity level: a high share of recruiting studies often signals that research interest is current and that new enrollment opportunities are appearing, while a low share typically means the field is dominated by completed or follow-up work where most participant spots have already been filled. These counts reflect the public registry only and include studies at every stage of design, so they should be read as an index of research attention rather than as a measure of treatment availability.

Phase 1 and Phase 2 studies focus on early safety signals, dosing, and preliminary effect, while Phase 3 studies are typically the larger efficacy and safety trials submitted toward regulatory review, and Phase 4 studies follow approved interventions in real-world use. A condition weighted toward later phases often reflects a mature research pipeline with several interventions already close to or past approval, whereas a heavier early-phase tilt suggests the field is still exploring new mechanisms and candidate approaches.

All figures are derived from the public ClinicalTrials.gov dataset maintained by the National Library of Medicine and are reproduced here for reference. Inclusion of a trial, sponsor, or intervention on this page is neither an endorsement nor a recommendation, eligibility, protocol changes, and site-level status can shift frequently, so always verify current details on ClinicalTrials.gov and consult a qualified healthcare provider before acting on anything you see here.

Frequently Asked Questions

How many clinical trials are there for Mental Health?

PlainTrial tracks 63 US clinical trials for Mental Health, of which 34 are currently recruiting participants. Data sourced from ClinicalTrials.gov.

How do I find a recruiting trial for Mental Health?

Use the trial list above filtered by "Recruiting" status, or visit our trial finder at /recruiting to search by condition and state. Always discuss trial participation with your healthcare provider before enrolling.

Is this data current?

Data is sourced from ClinicalTrials.gov and reflects our most recent data pull. Trial status may have changed since then. Always verify current information at ClinicalTrials.gov before making decisions about participation.

Disclaimer: This information is provided for informational purposes only and does not constitute professional advice. Data is sourced from ClinicalTrials.gov (National Library of Medicine). Consult a qualified professional before making decisions based on this data.

Source: ClinicalTrials.gov (NIH/NLM) ClinicalTrials.gov AACT registry · 2026 Trial counts and statuses sourced from ClinicalTrials.gov. Sponsor counts include both industry and federal/academic sponsors.

Verify with NIH →

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page aggregates every registered trial for this condition, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.