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ClinicalTrials.gov 6 recruiting now early-phase tilt small index

MDS (Myelodysplastic Syndrome): early-phase trial registry

6 of 7 indexed MDS (Myelodysplastic Syndrome) trials are currently recruiting, with more weight in Phase 1-2.

Corpus placement: #2,497 of 28,707 conditions by registered trial count.

7 US clinical trials · 6 currently recruiting · #2,497 of 28,707 conditions by registered trial count

MDS (Myelodysplastic Syndrome): 7 US clinical trials tracked, 6 recruiting.

MDS (Myelodysplastic Syndrome) is the subject of 7 registered US clinical trials on ClinicalTrials.gov, 6 of them currently open to new participants. 0 are in Phase 3-4 (later-stage) and 7 in Phase 1-2 (earlier-stage). The most active sponsor is National Heart, Lung, and Blood Institute (NHLBI), running 2 of these trials.

Enrollment posture brief

Registry condition mds-myelodysplastic-syndrome

OPEN 6 | RECR 86% | LATE 0 | EARLY 7 | RANK #2497 | SPON 2

Nearest open-share peer: Adenovirus (86% recruiting · 7 trials)

MDS (this)86%ACL Tear71.4%ACL57.1%Acute Myelogenous Leukemia42.9%Acne Scars28.6%
Open-enrollment share among volume-matched conditions near MDS (Myelodysplastic Syndrome)

MDS (Myelodysplastic Syndrome) lists 6 open slots (86% of 7 indexed trials). Peers are matched on registered volume, not therapeutic-area browse lists. How peer matching works →

Key findings

What ClinicalTrials.gov does not surface for MDS (Myelodysplastic Syndrome) on its own pages , computed from the registry mirror as of 2026-08-08. Each line carries its own denominator so it can be quoted as it stands.

  1. MDS (Myelodysplastic Syndrome) is recruiting above its size-band peers.

    6 of 7 indexed trials (85.7%) are open to enrollment, against a 46.5% average across 27,806 conditions with fewer than 20 trials. The peer set uses the same ClinicalTrials.gov-derived counts as this page.

  2. One sponsor concentrates MDS (Myelodysplastic Syndrome) research.

    National Heart, Lung, and Blood Institute (NHLBI) accounts for 2 of 7 trials (28.6%). 6 distinct sponsors appear on at least one study for this condition label.

  3. Typical MDS (Myelodysplastic Syndrome) enrolment sits around 60 participants.

    Median target enrolment is 60 among the 7 trials that report a genuine target (sentinel values excluded). 4 of those (57.1%) plan for fewer than 100 participants.

  4. MDS (Myelodysplastic Syndrome) research is mostly interventional.

    7 interventional and 0 observational studies make up this index (100% interventional). Study type is sponsor-reported on ClinicalTrials.gov.

Phase 14Phase 23

Open and recent trials

7 total, page 1 of 1

RECRUITING Phase 2 358 participants

A Platform Protocol to Investigate Post-Transplant Cyclophosphamide-Based Graft-Versus-Host Disease Prophylaxis in Patients With Hematologic Malignancies Undergoing Mismatched Unrelated Donor Peripheral Blood Stem Cell Transplantation

Center for International Blood and Marrow Transplant Research

NCT06859424

RECRUITING Phase 2 120 participants

Allogeneic Hematopoietic Stem Cell Transplantation for Severe Aplastic Anemia and Other Bone Marrow Failure Syndromes Using G-CSF Mobilized CD34+ Selected Hematopoietic Precursor Cells Co-Infused With a Reduced Dose of Non-Mobilized Donor T-cells

National Heart, Lung, and Blood Institute (NHLBI)

NCT01174108

RECRUITING Phase 1 100 participants

Phase 1/2: CD45RA Depleted Stem Cell Addback to Prevent Viral or Fungal Infections Post TCRab/CD19 Depleted HSCT

Children's Hospital of Philadelphia

NCT06839456

RECRUITING Phase 2 60 participants

Luspatercept + Darbepoetin in MDS

Yale University

NCT07096297

RECRUITING Phase 1 49 participants

Clinical Study of ARD103 CAR-T Therapy for Patients With R/R AML or MDS

ARCE Therapeutics

NCT06680752

RECRUITING Phase 1 12 participants

A First-in-Human Study of HLA-Partially to Fully Matched Allogenic Cryopreserved Deceased Donor Bone Marrow Transplantation for Patients With Hematologic Malignancies

Ossium Health

NCT05589896

COMPLETED Phase 1 41 participants

Preventing Stem Cell Transplant Complications With a Blood Separator Machine

National Heart, Lung, and Blood Institute (NHLBI)

NCT01866839

Phase Distribution

PhaseTrial count
Phase 1 4
Phase 2 3

Named interventions

Most-linked intervention names on MDS (Myelodysplastic Syndrome) records (sponsor-reported on ClinicalTrials.gov). Counts are trial links, not unique products.

Graft Manipulation (CD34+ Selection) Device
1 trials
ARD103 Biological
1 trials
Conditioning Regimen E Drug
1 trials
Conditioning Regimen D Drug
1 trials
Conditioning Regimen C Drug
1 trials
Conditioning Regimen B Drug
1 trials
Conditioning Regimen A Drug
1 trials
Phase 2 Established Dose from prior study, NCT03810196 Device
1 trials

US sites by state

Facility locations filed on MDS (Myelodysplastic Syndrome) trials. A trial with sites in several states counts in each.

Texas 4 trials
Oregon 2 trials
North Carolina 2 trials
Michigan 2 trials
Maryland 2 trials
Florida 2 trials
California 2 trials
Washington 1 trials

Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.

What to do with this MDS (Myelodysplastic Syndrome) page

7 registered trials, 6 currently recruiting, is a starting point for a conversation, not a diagnosis or a recommendation.

Trial and recruiting counts reflect ClinicalTrials.gov registry status as of the data vintage above; individual trial eligibility and enrollment status can change.

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This MDS (Myelodysplastic Syndrome) condition card totals 7 registered trials; most-linked intervention Graft Manipulation (CD34+ Selection); top US site state Texas. See our editorial standards & corrections policy, the methodology behind these numbers, the data changelog, or report a data error.