Medical Information Only. Consult your healthcare provider before considering clinical trial enrollment.
Malocclusion: later-stage trial registry
4 of 7 indexed Malocclusion trials are currently recruiting, with more weight in Phase 3-4.
Corpus placement: #2,497 of 28,707 conditions by registered trial count.
7 US clinical trials · 4 currently recruiting · #2,497 of 28,707 conditions by registered trial count
Malocclusion: 7 US clinical trials tracked, 4 recruiting.
Malocclusion is the subject of 7 registered US clinical trials on ClinicalTrials.gov, 4 of them currently open to new participants. 1 are in Phase 3-4 (later-stage) and 0 in Phase 1-2 (earlier-stage). The most active sponsor is University of North Carolina, Chapel Hill, running 2 of these trials.
Enrollment posture brief
Registry condition malocclusion
OPEN 4 | RECR 57% | LATE 1 | EARLY 0 | RANK #2497 | SPON 2
Volume-matched condition peers
Nearest open-share peer: Adverse Childhood Experiences (57% recruiting · 14 trials)
Malocclusion lists 4 open slots (57% of 7 indexed trials). Peers are matched on registered volume, not therapeutic-area browse lists. How peer matching works →
Key findings
What ClinicalTrials.gov does not surface for Malocclusion on its own pages , computed from the registry mirror as of 2026-08-08. Each line carries its own denominator so it can be quoted as it stands.
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Malocclusion is recruiting above its size-band peers.
4 of 7 indexed trials (57.1%) are open to enrollment, against a 46.5% average across 27,806 conditions with fewer than 20 trials. The peer set uses the same ClinicalTrials.gov-derived counts as this page.
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One sponsor concentrates Malocclusion research.
University of North Carolina, Chapel Hill accounts for 2 of 7 trials (28.6%). 6 distinct sponsors appear on at least one study for this condition label.
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Most Malocclusion trials plan to enrol fewer than 100 people.
Median target enrolment is 90 among the 7 trials that report a genuine target (sentinel values excluded). 5 of those (71.4%) plan for fewer than 100 participants.
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Malocclusion research is mostly interventional.
6 interventional and 1 observational studies make up this index (85.7% interventional). Study type is sponsor-reported on ClinicalTrials.gov.
Open and recent trials
7 total, page 1 of 1
Bromelain for Post-surgery Facial Swelling
Mohamed Bazina
NCT07115212
Orthognathic Speech Pathology: Phonetic Contrasts of Patients With Dental Discrepancies Pre- and Post-Treatment Analyses
University of North Carolina, Chapel Hill
NCT04117360
A Prospective Multicenter Clinical Investigation Evaluating the Accuracy of the Trimline Design When Treated With SureSmile® Aligners.
Dentsply Sirona Implants and Consumables
NCT07290790
Optimizing Orthodontic Appliances Efficiency With Remote Dental Monitoring and Artificial Intelligence Algorithms
University of Illinois at Chicago
NCT05573308
The Use of Clear Aligners With Movement Enhancement Techniques
Align Technology
NCT02087163
Effect of AcceleDent® Aura on Orthodontic Tooth Movement With Aligners
OrthoAccel Technologies
NCT01962012
Analysis of Orthodontic Tooth Movement Using 3D Imaging
University of North Carolina, Chapel Hill
NCT03398798
Phase Distribution
| Phase | Trial count |
|---|---|
| Phase 4 | 1 |
Top Sponsors
Named interventions
Most-linked intervention names on Malocclusion records (sponsor-reported on ClinicalTrials.gov). Counts are trial links, not unique products.
US sites by state
Facility locations filed on Malocclusion trials. A trial with sites in several states counts in each.
Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.
Related
What to do with this Malocclusion page
7 registered trials, 4 currently recruiting, is a starting point for a conversation, not a diagnosis or a recommendation.
- 4 Malocclusion trials are currently recruiting, check eligibility criteria before contacting a site. Browse recruiting trials
- University of North Carolina, Chapel Hill sponsors the most Malocclusion trials on record, review their full trial history before evaluating a specific study. See University of North Carolina, Chapel Hill's trials
- Bring the specific trial ID (NCT number) to your own doctor before enrolling, this page is a directory, not medical guidance. Read the trial-finding guide
Trial and recruiting counts reflect ClinicalTrials.gov registry status as of the data vintage above; individual trial eligibility and enrollment status can change.
Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This Malocclusion condition card totals 7 registered trials; most-linked intervention AcceleDent Aura; top US site state North Carolina. See our editorial standards & corrections policy, the methodology behind these numbers, the data changelog, or report a data error.