Medical Information Only. Always consult your healthcare provider before enrolling in any clinical trial.
NCT07115212 · ClinicalTrials.gov registry record · NA
Bromelain for Post-surgery Facial Swelling
A NA study of Malocclusion, sponsored by Mohamed Bazina.
- Recruiting
- Registry status
- NA
- Development phase
- 200
- Enrollment target
- 1
- Study location
NCT07115212: Recruiting NA study of Malocclusion, sponsored by Mohamed Bazina.
NCT07115212 is a NA study of Malocclusion that is actively recruiting participants, run by Mohamed Bazina. The registered enrollment target is 200 participants, above the 76-participant average among 6 other Malocclusion trials with a reported enrollment target (163% higher). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT07115212, a NA study of Malocclusion, is actively recruiting participants, sponsored by Mohamed Bazina.
- RECRUITING
- Registry status
- NA
- Development phase
- 200 participants
- Enrollment target
- 1
- Study location
Study Summary
The goal of this clinical trial is to learn if Bromelain Supplement works to decrease the amount of swelling or the amount of time swelling is present following jaw surgery. It will also learn about the safety of Bromelain supplement. The main questions it aims to answer are: Does Bromelain decrease facial swelling following orthognathic, or jaw, surgery? Does Bromelain supplement decrease the amount of time that patients are swollen following orthognathic, or jaw, surgery? Participants will: Take Bromelain supplement once daily for 9 days total. Take 2 days before surgery and 7 days following surgery. Keep a log of when the bromelain supplement is taken as well as another other medications. Visit the clinic with pre and post surgical protocol
Primary Outcome
Images will be obtained with the Vectra 3D imaging system to look at the volume of swelling in patients that undergo orthognathic surgery and measured in Cubic Centimeters. Will also have a heat map to visually show where swelling has increased or decreased since previously obtained imaging. All these images and measurements will be compared between the control and experimental groups.
Conditions Studied
Interventions
- DIETARY_SUPPLEMENT Bromelain
Study Locations (1)
Kentucky
- University of Kentucky - Lexington
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 200 participants |
| Start Date | 2025-09-08 |
| Est. Completion | 2026-04 |
| Phase | NA |
What NCT07115212 shows while recruiting
NCT07115212 is an interventional study that assigns participants to a tested intervention. The registered 200 participants enrollment target is mid-sized for trials with a published cap, above the 76-participant average among 6 other Malocclusion trials with a reported enrollment target (163% higher).
The record links to 1 condition, with Malocclusion appearing as the primary indexed condition, and to 1 intervention - of which Bromelain is the first listed.
NCT07115212 reports a single indexed study location in Kentucky.
Frequently Asked Questions
What is clinical trial NCT07115212 about?
NCT07115212 is a clinical study titled "Bromelain for Post-surgery Facial Swelling". The goal of this clinical trial is to learn if Bromelain Supplement works to decrease the amount of swelling or the amount of time swelling is present following jaw surgery. It will also learn about the safety of Bromelain supplement. The main questions it aims to answer are: Does Bromelain decreas...
What is the current status of trial NCT07115212?
This trial is currently recruiting. It is a NA study. The enrollment target is 200 participants. The study started on 2025-09-08. Estimated completion is 2026-04.
What conditions does trial NCT07115212 study?
This clinical trial studies the following conditions: Malocclusion.
What interventions are being tested in trial NCT07115212?
The interventions under investigation include: Bromelain (DIETARY_SUPPLEMENT).
Who is sponsoring clinical trial NCT07115212?
This trial is sponsored by Mohamed Bazina, which has 1 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT07115212 being conducted?
This trial has 1 study location across Kentucky. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
Similar trials for Malocclusion
Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.
-
A Prospective Multicenter Clinical Investigation Evaluating the Accuracy of the Trimline Design When Treated With SureSmile® Aligners.
RECRUITING · NA
-
Optimizing Orthodontic Appliances Efficiency With Remote Dental Monitoring and Artificial Intelligence Algorithms
RECRUITING · NA
-
Analysis of Orthodontic Tooth Movement Using 3D Imaging
COMPLETED · NA
-
The Use of Clear Aligners With Movement Enhancement Techniques
COMPLETED · NA
-
Orthognathic Speech Pathology: Phonetic Contrasts of Patients With Dental Discrepancies Pre- and Post-Treatment Analyses
RECRUITING
-
Effect of AcceleDent® Aura on Orthodontic Tooth Movement With Aligners
COMPLETED · Phase 4
Nationwide trials with similar profiles
Cross-condition peers matched on enrollment target and registry start date, not the same-condition list above.
Similar enrollment target
- NCT00107289 · 200 participants · Phase 2
Iodine I 131 Metaiodobenzylguanidine in Treating Patients With Recurrent, Progressive, or Refractory Neuroblastoma or Malignant Pheochromocytoma or Paraganglioma
- NCT00109174 · 200 participants · NA
MRS Measurement of Glutamate and GABA Metabolism in Brain
- NCT00177268 · 200 participants
Blood, Urine, and Tissue Collection for Cutaneous Lymphoma, Eczema, and Atopic Dermatitis Research
- NCT00493688 · 200 participants
A Study to Determine Whether Perioperative Energy Dynamics Correlates With Postoperative Outcomes
Similar registry start date
- NCT05962346 · started 2026-12 · NA
Fetal Endoscopic Tracheal Occlusion for Congenital Diaphragmatic Hernia
- NCT07125183 · started 2026-12 · Phase 2
Study on Efficacy and Tolerability of Weekly Doxorubicin in Elderly Patients With Advanced or Metastatic Leiomyosarcoma
- NCT07292298 · started 2026-11 · Phase 2
Phase 2 Single-Arm Rectal Cancer Brachytherapy for Patients With Low-Lying Residual Adenocarcinoma After Total Neoadjuvant Therapy to Improve Organ Preservation Rates
- NCT04263285 · started 2026-10 · NA
Treatment of Depression Post-SCI