Medical Information Only. Consult your healthcare provider before considering clinical trial enrollment.
Li-Fraumeni Syndrome clinical trials
5 of 7 indexed Li-Fraumeni Syndrome trials are currently recruiting.
Corpus placement: #2,497 of 28,707 conditions by registered trial count.
7 US clinical trials · 5 currently recruiting · #2,497 of 28,707 conditions by registered trial count
Li-Fraumeni Syndrome: 7 US clinical trials tracked, 5 recruiting.
Li-Fraumeni Syndrome is the subject of 7 registered US clinical trials on ClinicalTrials.gov, 5 of them currently open to new participants. The most active sponsor is Dana-Farber Cancer Institute, running 2 of these trials.
Enrollment posture brief
Registry condition li-fraumeni-syndrome
OPEN 5 | RECR 71% | LATE 0 | EARLY 0 | RANK #2497 | SPON 2
Volume-matched condition peers
Nearest open-share peer: Advanced Endometrial Carcinoma (71% recruiting · 7 trials)
Li-Fraumeni Syndrome lists 5 open slots (71% of 7 indexed trials). Peers are matched on registered volume, not therapeutic-area browse lists. How peer matching works →
Key findings
What ClinicalTrials.gov does not surface for Li-Fraumeni Syndrome on its own pages , computed from the registry mirror as of 2026-08-08. Each line carries its own denominator so it can be quoted as it stands.
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Li-Fraumeni Syndrome is recruiting above its size-band peers.
5 of 7 indexed trials (71.4%) are open to enrollment, against a 46.5% average across 27,806 conditions with fewer than 20 trials. The peer set uses the same ClinicalTrials.gov-derived counts as this page.
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One sponsor concentrates Li-Fraumeni Syndrome research.
Dana-Farber Cancer Institute accounts for 2 of 7 trials (28.6%). 5 distinct sponsors appear on at least one study for this condition label.
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Typical Li-Fraumeni Syndrome enrolment sits around 500 participants.
Median target enrolment is 500 among the 7 trials that report a genuine target (sentinel values excluded). 1 of those (14.3%) plan for fewer than 100 participants.
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Li-Fraumeni Syndrome research leans observational.
1 interventional and 6 observational studies make up this index (14.3% interventional). Study type is sponsor-reported on ClinicalTrials.gov.
Open and recent trials
7 total, page 1 of 1
Characterization of Patients With Uncommon Presentations and/or Uncommon Diseases Associated With the Cardiovascular System
National Heart, Lung, and Blood Institute (NHLBI)
NCT01143454
Clinical and Genetic Studies of Li-Fraumeni Syndrome
National Cancer Institute (NCI)
NCT01443468
Li-Fraumeni & TP53 (LiFT UP): Understanding and Progress
Dana-Farber Cancer Institute
NCT04541654
Willingness to Participate in a Trial Comparing Standard Genetic Counseling Versus Personalized Genetic Counseling
M.D. Anderson Cancer Center
NCT05126810
Li-Fraumeni Syndrome/TP53 Biobank
Abramson Cancer Center at Penn Medicine
NCT04367246
Screening With Whole Body MRI For Detection Of Primary Tumors In Children And Adults With Li-Fraumeni Syndrome (LFS) And Other Cancer Predisposition Syndromes
Dana-Farber Cancer Institute
NCT02950987
Exploring How to Adapt an Evidence-Based Mindful Self-Compassion Program for Young Adults With Li-Fraumeni Syndrome
National Cancer Institute (NCI)
NCT07032922
Phase Distribution
Phase data not available
Top Sponsors
Named interventions
Most-linked intervention names on Li-Fraumeni Syndrome records (sponsor-reported on ClinicalTrials.gov). Counts are trial links, not unique products.
US sites by state
Facility locations filed on Li-Fraumeni Syndrome trials. A trial with sites in several states counts in each.
Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.
Related
What to do with this Li-Fraumeni Syndrome page
7 registered trials, 5 currently recruiting, is a starting point for a conversation, not a diagnosis or a recommendation.
- 5 Li-Fraumeni Syndrome trials are currently recruiting, check eligibility criteria before contacting a site. Browse recruiting trials
- Dana-Farber Cancer Institute sponsors the most Li-Fraumeni Syndrome trials on record, review their full trial history before evaluating a specific study. See Dana-Farber Cancer Institute's trials
- Bring the specific trial ID (NCT number) to your own doctor before enrolling, this page is a directory, not medical guidance. Read the trial-finding guide
Trial and recruiting counts reflect ClinicalTrials.gov registry status as of the data vintage above; individual trial eligibility and enrollment status can change.
Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This Li-Fraumeni Syndrome condition card totals 7 registered trials; most-linked intervention Whole Body MRI; top US site state Maryland. See our editorial standards & corrections policy, the methodology behind these numbers, the data changelog, or report a data error.