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NCT04553900 · ClinicalTrials.gov registry record · NA
Effect of Heat Stress on Global LV Function in Anesthetized Humans
A NA study of Hyperthermia and Cardiac Functional Disturbances During Surgery, sponsored by University of California, San Diego.
- Completed
- Registry status
- NA
- Development phase
- 28
- Enrollment target
- 1
- Study location
NCT04553900 is a NA study of Hyperthermia and Cardiac Functional Disturbances During Surgery that has completed, run by University of California, San Diego. The registered enrollment target is 28 participants, below the 48-participant average among 15 other Hyperthermia trials with a reported enrollment target (42% lower). The trial reports 1 study location across 1 state.
The verdict
NCT04553900, a NA study of Hyperthermia and Cardiac Functional Disturbances During Surgery, has completed, sponsored by University of California, San Diego.
- COMPLETED
- Registry status
- NA
- Development phase
- 28 participants
- Enrollment target
- 1
- Study location
Study Summary
Recent data suggests that increased temperature improves inotropic function during systole and may improve diastolic function in healthy humans at rest, despite a reduction in left ventricular volume at end diastole. The effect of heat stress has not been reported in patients receiving general anesthesia and the impact of general anesthesia on these findings is not known. Trans-esophageal echocardiography will be used to measure parameters important to both systolic and diastolic function at temperature intervals of 1°C in patients undergoing "Heated Intraoperative Peritoneal Chemotherapy" (HIPEC.) That general anesthesia will not alter the cardiovascular effects of increased temperature that has been reported in healthy, un-anesthetized humans is the hypothesis.
Conditions Studied
Interventions
- DIAGNOSTIC_TEST Transesophageal Echocardiography
Study Locations (1)
California
- University of California, San Diego - La Jolla
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 28 participants |
| Start Date | 2017-06-09 |
| Est. Completion | 2019-12-06 |
| Phase | NA |
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Full Details on ClinicalTrials.gov ↗What the Registry Record Tells You About NCT04553900
The ClinicalTrials.gov registry entry for NCT04553900 describes a study currently listed as completed, categorized as NA. The registered enrollment target is 28 participants, a figure that helps gauge the scale of data the investigators plan to collect, below the 48-participant average among 15 other Hyperthermia trials with a reported enrollment target (42% lower). The listed sponsor is University of California, San Diego, which has 775 total studies on file at ClinicalTrials.gov.
The record links to 2 conditions, with Hyperthermia appearing as the primary indexed condition, and to 1 intervention - of which Transesophageal Echocardiography is the first listed.
NCT04553900 reports 1 study location spanning 1 distinct geographic area - top geographies include California.
Frequently Asked Questions
What is clinical trial NCT04553900 about?
NCT04553900 is a clinical study titled "Effect of Heat Stress on Global LV Function in Anesthetized Humans". Recent data suggests that increased temperature improves inotropic function during systole and may improve diastolic function in healthy humans at rest, despite a reduction in left ventricular volume at end diastole. The effect of heat stress has not been reported in patients receiving general anest...
What is the current status of trial NCT04553900?
This trial is currently completed. It is a NA study. The enrollment target is 28 participants. The study started on 2017-06-09. Estimated completion is 2019-12-06.
What conditions does trial NCT04553900 study?
This clinical trial studies the following conditions: Hyperthermia, Cardiac Functional Disturbances During Surgery.
What interventions are being tested in trial NCT04553900?
The interventions under investigation include: Transesophageal Echocardiography (DIAGNOSTIC_TEST).
Who is sponsoring clinical trial NCT04553900?
This trial is sponsored by University of California, San Diego, which has 775 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT04553900 being conducted?
This trial has 1 study location across California. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
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