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ClinicalTrials.gov 15 recruiting now official registry

Hpv clinical trials

15 of 25 indexed Hpv trials are currently recruiting.

25 US clinical trials · 15 currently recruiting

Hpv is the subject of 25 registered US clinical trials on ClinicalTrials.gov, 15 of them currently open to new participants. 2 are in Phase 3-4 (later-stage) and 7 in Phase 1-2 (earlier-stage). The most active sponsor is National Cancer Institute (NCI), running 3 of these trials.

The research picture

Hpv has 25 registered US clinical trials, 15 of them open to new participants right now, about 60% of the total.

15
recruiting participants now
60%
of trials open to enrollment
2
in Phase 3–4 (later-stage)
3
top sponsor: National Cancer Institute (NCI)
Phase 12Phase 25Phase 42

Active & Recent Trials

25 total, page 1 of 1

RECRUITING NA 16,000 participants

Stand Up 2 HPV: Standing Orders to Improve HPV Vaccination

University of Rochester

NCT06380114

RECRUITING NA 3,100 participants

The HPV 9-10 Trial: Early Initiation of HPV Vaccination

University of Colorado, Denver

NCT04722822

RECRUITING NA 1,000 participants

HPV Self-Collection Program

University of Utah

NCT06674681

RECRUITING NA 920 participants

Prevención en Sus Manos: Feasibility of a Novel Community-Based Strategy to Improve Access to Cervical Cancer Screening

M.D. Anderson Cancer Center

NCT06109870

RECRUITING 600 participants

The Natural History of Severe Viral Infections and Characterization of Immune Defects in Patients Without Known Immunocompromise

National Institute of Allergy and Infectious Diseases (NIAID)

NCT01011712

RECRUITING NA 450 participants

Evaluation of the Q-Pad hrHPV Test System for Identifying Precancer

Qurasense

NCT07281599

RECRUITING NA 180 participants

Playing Game to Learn About Children's Vaccine Project

Michigan State University

NCT05984849

RECRUITING Phase 2 121 participants

A Study of Reduced Radiation Therapy and Standard-of-Care Chemotherapy in People With HPV-Positive Throat Cancer

Memorial Sloan Kettering Cancer Center

NCT05491512

RECRUITING NA 120 participants

PopSci CHW4CervixHealth

Thomas Jefferson University

NCT07336134

RECRUITING Phase 4 100 participants

HPV Vaccine Reduced Dose

Emory University

NCT06799494

RECRUITING Phase 1 98 participants

TheraT® Vectors (Vaccines) Combined With Chemotherapy to Treat HPV16 Head and Neck Cancers

University of Chicago

NCT05108870

RECRUITING Phase 2 38 participants

Response-Adaptive Treatment in Untreated Locoregional HPV-Negative Head and Neck Cancer

University of Chicago

NCT07065630

RECRUITING Phase 2 30 participants

A Study on Using Cell-Free Tumor DNA (ctDNA) Testing to Decide When to StartRoutine Treatment in People With Human Papilloma Virus (HPV)- Associated Oropharynx Cancer (OPC)

Memorial Sloan Kettering Cancer Center

NCT05307939

RECRUITING NA 30 participants

Treatment De-Escalation for Favorable Prognosis Human Papilloma Virus (HPV) or p16-Positive Oropharyngeal Cancer Receiving Definitive Radiotherapy

Georgetown University

NCT06902623

RECRUITING Phase 2 20 participants

BALSTILIMAB on Viral Clearance in HPV+ Oropharyngeal Cancer Patients

M.D. Anderson Cancer Center

NCT05363709

ACTIVE NOT RECRUITING NA 21,110 participants

Text and Talk: A Multi-level Intervention to Increase Provider HPV Vaccine Recommendation Effectiveness

University of Florida

NCT05006833

ACTIVE NOT RECRUITING NA 870 participants

SELF-CERV Pivotal Study: SELF-Collection for CERVical Cancer Screening

Teal Health

NCT06120205

ACTIVE NOT RECRUITING NA 200 participants

Advancing Cervical Cancer Screening Through the Emergency Department - IIS

University of Rochester

NCT06796738

ACTIVE NOT RECRUITING 150 participants

Post-treatment Surveillance in HPV+ Oropharyngeal SCC

Dana-Farber Cancer Institute

NCT04965792

ACTIVE NOT RECRUITING Phase 1 55 participants

A Phase I/II Study of Combination Immunotherapy for Advanced Cancers Including HPV-Associated Malignancies, Small Bowel, and Colon Cancers

National Cancer Institute (NCI)

NCT04708470

ACTIVE NOT RECRUITING Phase 4 17 participants

Assessing Durable Antibody Response to HPV Vaccination

Emory University

NCT05031078

COMPLETED 7,500 participants

Low-Cost Molecular Cervical Cancer Screening Study

National Cancer Institute (NCI)

NCT01231945

COMPLETED Phase 2 614 participants

Human Papillomavirus (HPV) Vaccination Acceptance by African-American Parents: Identifying Psychosocial Barriers

Syracuse University

NCT00680147

COMPLETED 300 participants

Pilots of Self-Collection for HPV DNA Detection

National Cancer Institute (NCI)

NCT00342511

COMPLETED NA 170 participants

Pilot HPV Vaccination in Chinese American Community

Temple University

NCT04505930

Phase Distribution

PhaseTrial count
Phase 1 2
Phase 2 5
Phase 4 2

Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.

Reading the Hpv Trial Landscape

25 indexed Hpv studies · 15 recruiting (60%).

Phase mix: 2 late (III/IV) vs 7 early (I/II).

Top sponsor: National Cancer Institute (NCI) (3 trials), 9 others listed. 25 shown below, recruiting first.

How to read this condition's trial landscape

That ratio is a useful proxy for activity level: a high share of recruiting studies often signals that research interest is current and that new enrollment opportunities are appearing, while a low share typically means the field is dominated by completed or follow-up work where most participant spots have already been filled. These counts reflect the public registry only and include studies at every stage of design, so they should be read as an index of research attention rather than as a measure of treatment availability.

Phase 1 and Phase 2 studies focus on early safety signals, dosing, and preliminary effect, while Phase 3 studies are typically the larger efficacy and safety trials submitted toward regulatory review, and Phase 4 studies follow approved interventions in real-world use. A condition weighted toward later phases often reflects a mature research pipeline with several interventions already close to or past approval, whereas a heavier early-phase tilt suggests the field is still exploring new mechanisms and candidate approaches.

All figures are derived from the public ClinicalTrials.gov dataset maintained by the National Library of Medicine and are reproduced here for reference. Inclusion of a trial, sponsor, or intervention on this page is neither an endorsement nor a recommendation, eligibility, protocol changes, and site-level status can shift frequently, so always verify current details on ClinicalTrials.gov and consult a qualified healthcare provider before acting on anything you see here.

Frequently Asked Questions

How many clinical trials are there for Hpv?

PlainTrial tracks 25 US clinical trials for Hpv, of which 15 are currently recruiting participants. Data sourced from ClinicalTrials.gov.

How do I find a recruiting trial for Hpv?

Use the trial list above filtered by "Recruiting" status, or visit our trial finder at /recruiting to search by condition and state. Always discuss trial participation with your healthcare provider before enrolling.

Is this data current?

Data is sourced from ClinicalTrials.gov and reflects our most recent data pull. Trial status may have changed since then. Always verify current information at ClinicalTrials.gov before making decisions about participation.

Disclaimer: This information is provided for informational purposes only and does not constitute professional advice. Data is sourced from ClinicalTrials.gov (National Library of Medicine). Consult a qualified professional before making decisions based on this data.

Source: ClinicalTrials.gov (NIH/NLM) ClinicalTrials.gov AACT registry · 2026 Trial counts and statuses sourced from ClinicalTrials.gov. Sponsor counts include both industry and federal/academic sponsors.

Verify with NIH →

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page aggregates every registered trial for this condition, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.