Medical Information Only. Consult your healthcare provider before considering clinical trial enrollment.
Healthy Volunteers: early-phase trial registry
79 of 284 indexed Healthy Volunteers trials are currently recruiting, with more weight in Phase 1-2.
Corpus placement: #32 of 28,707 conditions by registered trial count.
284 US clinical trials · 79 currently recruiting · #32 of 28,707 conditions by registered trial count
Healthy Volunteers: 284 US clinical trials tracked, 79 recruiting.
Healthy Volunteers is the subject of 284 registered US clinical trials on ClinicalTrials.gov, 79 of them currently open to new participants. 6 are in Phase 3-4 (later-stage) and 206 in Phase 1-2 (earlier-stage). The most active sponsor is Takeda, running 16 of these trials.
Enrollment posture brief
Registry condition healthy-volunteers
OPEN 79 | RECR 28% | LATE 6 | EARLY 206 | RANK #32 | SPON 16
Volume-matched condition peers
Nearest open-share peer: Arrhythmias, Cardiac (28% recruiting · 18 trials)
Healthy Volunteers lists 79 open slots (28% of 284 indexed trials). Peers are matched on registered volume, not therapeutic-area browse lists. How peer matching works →
Key findings
What ClinicalTrials.gov does not surface for Healthy Volunteers on its own pages , computed from the registry mirror as of 2026-08-08. Each line carries its own denominator so it can be quoted as it stands.
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Healthy Volunteers is recruiting below its size-band peers.
79 of 284 indexed trials (27.8%) are open to enrollment, against a 37.1% average across 139 conditions with 100+ trials. The peer set uses the same ClinicalTrials.gov-derived counts as this page.
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Sponsorship of Healthy Volunteers trials is spread across many organizations.
Takeda accounts for 16 of 284 trials (5.6%). 144 distinct sponsors appear on at least one study for this condition label.
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Most Healthy Volunteers trials plan to enrol fewer than 100 people.
Median target enrolment is 48 among the 284 trials that report a genuine target (sentinel values excluded). 204 of those (71.8%) plan for fewer than 100 participants.
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Healthy Volunteers research is mostly interventional.
251 interventional and 33 observational studies make up this index (88.4% interventional). Study type is sponsor-reported on ClinicalTrials.gov.
Open and recent trials
284 total, page 6 of 6
Bioavailability of Phytonutrients From Novel Preparations of Broccoli
USDA Beltsville Human Nutrition Research Center
NCT03773497
Effect of Short Term Growth Hormone Releasing Hormone in Healthy Men
Massachusetts General Hospital
NCT00850564
A Study to Assess the Effect of Cefiderocol on the Pharmacokinetics (PK) of Midazolam in Healthy Participants
Shionogi
NCT05395104
A Study to Evaluate the Effect of [14C]Acp-196 (Acalabrutinib) in Healthy Adult Participants
Acerta Pharma
NCT04898101
Effect of Administration of Itraconazole on the Pharmacokinetics of S-309309 in Healthy Participants
Shionogi
NCT06106334
A Study to Evaluate the Effect of High-Fat Meal on TAK-788 Pharmacokinetics (PK) in Healthy Adult Participants
Takeda
NCT04441255
PET Imaging of Nicotinic Acetylcholine Receptors
National Institute on Drug Abuse (NIDA)
NCT01046513
Effect of Copanlisib on Metformin Pharmacokinetics and Pharmacodynamics
Bayer
NCT03655301
A Study of LY3015014 in Healthy Participants With High Cholesterol
Eli Lilly and Company
NCT01671085
Ascending Dose Study of the Safety of AB-SA01 When Topically Applied to Intact Skin of Healthy Adults
Armata Pharmaceuticals
NCT02757755
A Midazolam Drug Interaction Study With PF-04171327
Pfizer
NCT00987038
Measuring Single-Serving Grain Intake
USDA Beltsville Human Nutrition Research Center
NCT03783637
Study to Evaluate the Effect of Multiple-Dose Ritlecitinib on the Pharmacokinetics (PK) of Tolbutamide
Pfizer
NCT05097716
A Study of Axiron® in Healthy Participants
Eli Lilly and Company
NCT02004132
A Study to Investigate the Effects of Itraconazole on the Pharmacokinetics of PC14586 in Healthy Participants
PMV Pharmaceuticals
NCT06362642
Cardiac Water and Fluoromethane Cardiac PET
University of Wisconsin, Madison
NCT00205127
Hemin in Healthy Subjects
Mayo Clinic
NCT00882804
Study of the Effect of Food and a Proton Pump Inhibitor (PPI; Omeprazole) on LOXO-305 in Healthy Participants
Loxo Oncology
NCT05134350
Phase 1 Evaluation of [18F]MK-6240 PET as an Imaging Marker for Tau Protein
Invicro
NCT03071224
Effects of Ferrous Sulfate on the Pharmacokinetics of AKB-6548
Akebia Therapeutics
NCT02327546
A Study to Learn How [14C]ASP0367 is Processed by the Body in Healthy Men
Astellas Pharma Global Development
NCT05217901
Pharmacokinetic and Mass Balance Study of Orally Administered [14C]-AZD4205 in Healthy Adult Male Volunteers
Dizal Pharmaceuticals
NCT04225208
Safety Study of Acellular Adipose Tissue for Soft Tissue Reconstruction
Johns Hopkins University
NCT02817984
Study of the Absorption, Metabolism, and Excretion of [14C]-Tebipenem Pivoxil Hydrobromide (TBPM-PI-HBr) Following a Single Oral Dose in Healthy Male Subjects
Spero Therapeutics
NCT04625855
A Study to Evaluate the Absorption, Metabolism, and Excretion of Orally Administered [14C]-BMS-986368 in Healthy Male Participants
Celgene
NCT06227975
Testing Potential Synergistic Effects of Albuterol and Caffeine on Metabolic Rate
Pennington Biomedical Research Center
NCT02135965
A Trial to Study the Absorption, Metabolism, and Excretion of [14C]-Olinciguat in Healthy Male Volunteers
Cyclerion Therapeutics
NCT03795519
A Study of LY2157299 Monohydrate in Healthy Volunteers
Eli Lilly and Company
NCT01746004
A Study to Evaluate Lemborexant in Milk of Healthy Lactating Women
Eisai
NCT04890561
A Pharmacokinetic Study of [14C]-GDC-0810 After Single Oral Administration in Healthy Female Participants
Genentech
NCT02802670
Phase 0 Study of [18F]MNI-968 as a Marker for D1 Receptor in Healthy Subjects
Molecular NeuroImaging
NCT03082768
A Study to Investigate the Safety, Tolerability, Pharmacokinetics (PK) and Pharmacodynamics (PD) of TAK-954 in Healthy Adult Participants
Millennium Pharmaceuticals
NCT03870555
Study to Evaluate the Safety and Dosimetry of [68Ga]-NOTA-hGZP (CSB-111) PET Imaging in Healthy Human Volunteers.
Cytosite Biopharma
NCT05285696
Single-dose AME Study With [14C]AR882 in Healthy Male Subjects
Arthrosi Therapeutics
NCT04508426
Phase Distribution
| Phase | Trial count |
|---|---|
| Phase 1 | 198 |
| Phase 2 | 8 |
| Phase 4 | 6 |
Top Sponsors
Named interventions
Most-linked intervention names on Healthy Volunteers records (sponsor-reported on ClinicalTrials.gov). Counts are trial links, not unique products.
US sites by state
Facility locations filed on Healthy Volunteers trials. A trial with sites in several states counts in each.
Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.
Related
What to do with this Healthy Volunteers page
284 registered trials, 79 currently recruiting, is a starting point for a conversation, not a diagnosis or a recommendation.
- 79 Healthy Volunteers trials are currently recruiting, check eligibility criteria before contacting a site. Browse recruiting trials
- Takeda sponsors the most Healthy Volunteers trials on record, review their full trial history before evaluating a specific study. See Takeda's trials
- Bring the specific trial ID (NCT number) to your own doctor before enrolling, this page is a directory, not medical guidance. Read the trial-finding guide
Trial and recruiting counts reflect ClinicalTrials.gov registry status as of the data vintage above; individual trial eligibility and enrollment status can change.
Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This Healthy Volunteers condition card totals 284 registered trials; most-linked intervention Placebo; top US site state Maryland. See our editorial standards & corrections policy, the methodology behind these numbers, the data changelog, or report a data error.