Medical Information Only. Consult your healthcare provider before considering clinical trial enrollment.
Harm Reduction: later-stage trial registry
6 of 8 indexed Harm Reduction trials are currently recruiting, with more weight in Phase 3-4.
Corpus placement: #2,176 of 28,707 conditions by registered trial count.
8 US clinical trials · 6 currently recruiting · #2,176 of 28,707 conditions by registered trial count
Harm Reduction: 8 US clinical trials tracked, 6 recruiting.
Harm Reduction is the subject of 8 registered US clinical trials on ClinicalTrials.gov, 6 of them currently open to new participants. 3 are in Phase 3-4 (later-stage) and 0 in Phase 1-2 (earlier-stage). The most active sponsor is Nationwide Children's Hospital, running 1 of these trials.
Enrollment posture brief
Registry condition harm-reduction
OPEN 6 | RECR 75% | LATE 3 | EARLY 0 | RANK #2176 | SPON 1
Volume-matched condition peers
Nearest open-share peer: Adolescent Idiopathic Scoliosis (75% recruiting · 8 trials)
Harm Reduction lists 6 open slots (75% of 8 indexed trials). Peers are matched on registered volume, not therapeutic-area browse lists. How peer matching works →
Key findings
What ClinicalTrials.gov does not surface for Harm Reduction on its own pages , computed from the registry mirror as of 2026-08-08. Each line carries its own denominator so it can be quoted as it stands.
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Harm Reduction is recruiting above its size-band peers.
6 of 8 indexed trials (75%) are open to enrollment, against a 46.5% average across 27,806 conditions with fewer than 20 trials. The peer set uses the same ClinicalTrials.gov-derived counts as this page.
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Sponsorship of Harm Reduction trials is spread across many organizations.
Nationwide Children's Hospital accounts for 1 of 8 trials (12.5%). 8 distinct sponsors appear on at least one study for this condition label.
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Typical Harm Reduction enrolment sits around 300 participants.
Median target enrolment is 300 among the 8 trials that report a genuine target (sentinel values excluded). 2 of those (25%) plan for fewer than 100 participants.
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Harm Reduction research is mostly interventional.
7 interventional and 1 observational studies make up this index (87.5% interventional). Study type is sponsor-reported on ClinicalTrials.gov.
Open and recent trials
8 total, page 1 of 1
Vending Machine Naloxone Distribution for Your Community (VENDY)
University of Colorado, Denver
NCT06429436
Teaching Health Resilience in a Hospital Setting: A Peer-led Intervention
University of Pennsylvania
NCT06843213
A Randomized Clinical Trial of a Novel Drug Education and Diversion Program (iDECIDE) for Middle and High School Students
Massachusetts General Hospital
NCT06115746
Noncombustible Nicotine Delivery Systems as Potential Harm Reduction Tools for Persistent Cigarette Smokers
Abramson Cancer Center at Penn Medicine
NCT06372899
Electronic Harm Reduction Treatment for Alcohol
University of Washington
NCT06702007
Shelter HArm Reduction Evaluation
NYU Langone Health
NCT07170072
Evaluating an Intervention to Prevent Overdoses in Rural and Urban Counties
Nationwide Children's Hospital
NCT05463341
Implementation of Onsite, Rapid ART Initiation Among People Who Inject Drugs Living With HIV at Syringe Services Program
University of Miami
NCT04650269
Phase Distribution
| Phase | Trial count |
|---|---|
| Phase 3 | 1 |
| Phase 4 | 2 |
Top Sponsors
Named interventions
Most-linked intervention names on Harm Reduction records (sponsor-reported on ClinicalTrials.gov). Counts are trial links, not unique products.
US sites by state
Facility locations filed on Harm Reduction trials. A trial with sites in several states counts in each.
Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.
Related
What to do with this Harm Reduction page
8 registered trials, 6 currently recruiting, is a starting point for a conversation, not a diagnosis or a recommendation.
- 6 Harm Reduction trials are currently recruiting, check eligibility criteria before contacting a site. Browse recruiting trials
- Nationwide Children's Hospital sponsors the most Harm Reduction trials on record, review their full trial history before evaluating a specific study. See Nationwide Children's Hospital's trials
- Bring the specific trial ID (NCT number) to your own doctor before enrolling, this page is a directory, not medical guidance. Read the trial-finding guide
Trial and recruiting counts reflect ClinicalTrials.gov registry status as of the data vintage above; individual trial eligibility and enrollment status can change.
Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This Harm Reduction condition card totals 8 registered trials; most-linked intervention HIV care; top US site state Pennsylvania. See our editorial standards & corrections policy, the methodology behind these numbers, the data changelog, or report a data error.