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ClinicalTrials.gov 9 recruiting now official registry

Graves Disease clinical trials

9 of 12 indexed Graves Disease trials are currently recruiting.

12 US clinical trials · 9 currently recruiting

Graves Disease is the subject of 12 registered US clinical trials on ClinicalTrials.gov, 9 of them currently open to new participants. 1 are in Phase 3-4 (later-stage) and 7 in Phase 1-2 (earlier-stage). The most active sponsor is Immunovant Sciences, running 2 of these trials.

The research picture

Graves Disease has 12 registered US clinical trials, 9 of them open to new participants right now, about 75% of the total.

9
recruiting participants now
75%
of trials open to enrollment
1
in Phase 3–4 (later-stage)
2
top sponsor: Immunovant Sciences
Phase 12Phase 25Phase 41

Active & Recent Trials

12 total, page 1 of 1

RECRUITING 2,500 participants

Natural History of Thyroid Function Disorders

National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)

NCT00001159

RECRUITING Phase 2 240 participants

A Study to Assess the Efficacy, Safety, and Tolerability of IMVT-1402 as Treatment for Adult Participants With Graves' Disease

Immunovant Sciences

NCT06727604

RECRUITING Phase 2 210 participants

A Study to Assess the Efficacy, Safety, and Tolerability of IMVT-1402 as Treatment for Adult Participants With Graves' Disease

Immunovant Sciences

NCT07018323

RECRUITING Phase 1 100 participants

NEXUS Study: A Study to Test Single and Multiple Doses of MER511 Given to Adults With Graves' Disease

Merida Biosciences

NCT07305818

RECRUITING 100 participants

The Effect of Teprotumumab on Thyroid Eye Disease and Thyroid Dysfunction

Walter Reed National Military Medical Center

NCT06275373

RECRUITING Phase 4 76 participants

Preoperative Corticosteroids in Autoimmune Thyroid Disease

Indiana University

NCT05435547

RECRUITING Phase 2 30 participants

Impact of Vitamin D Therapy on Thyroid Function and Antibody Levels in Pediatric Graves' Disease

Northwell Health

NCT07369063

RECRUITING Phase 1 15 participants

Study of BHV-1300 in Graves' Disease

Biohaven Therapeutics

NCT06980649

RECRUITING NA 10 participants

Personalized Treatment in Thyroid Disorders

Johns Hopkins University

NCT03517579

COMPLETED NA 93 participants

Shared Decision Making in Graves Disease - Graves Disease (GD) Choice

Mayo Clinic

NCT02107794

COMPLETED Phase 2 19 participants

Radioactive Iodide Therapy for Pediatric Graves' Disease

University of Florida

NCT01269749

COMPLETED Phase 2 15 participants

A Study to Evaluate the Safety and Effect of CFZ533 on Patients With Graves' Disease

Novartis Pharmaceuticals

NCT02713256

Phase Distribution

PhaseTrial count
Phase 1 2
Phase 2 5
Phase 4 1

Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.

Reading the Graves Disease Trial Landscape

12 indexed Graves Disease studies · 9 recruiting (75%).

Phase mix: 1 late (III/IV) vs 7 early (I/II).

Top sponsor: Immunovant Sciences (2 trials), 9 others listed. 12 shown below, recruiting first.

How to read this condition's trial landscape

That ratio is a useful proxy for activity level: a high share of recruiting studies often signals that research interest is current and that new enrollment opportunities are appearing, while a low share typically means the field is dominated by completed or follow-up work where most participant spots have already been filled. These counts reflect the public registry only and include studies at every stage of design, so they should be read as an index of research attention rather than as a measure of treatment availability.

Phase 1 and Phase 2 studies focus on early safety signals, dosing, and preliminary effect, while Phase 3 studies are typically the larger efficacy and safety trials submitted toward regulatory review, and Phase 4 studies follow approved interventions in real-world use. A condition weighted toward later phases often reflects a mature research pipeline with several interventions already close to or past approval, whereas a heavier early-phase tilt suggests the field is still exploring new mechanisms and candidate approaches.

All figures are derived from the public ClinicalTrials.gov dataset maintained by the National Library of Medicine and are reproduced here for reference. Inclusion of a trial, sponsor, or intervention on this page is neither an endorsement nor a recommendation, eligibility, protocol changes, and site-level status can shift frequently, so always verify current details on ClinicalTrials.gov and consult a qualified healthcare provider before acting on anything you see here.

Frequently Asked Questions

How many clinical trials are there for Graves Disease?

PlainTrial tracks 12 US clinical trials for Graves Disease, of which 9 are currently recruiting participants. Data sourced from ClinicalTrials.gov.

How do I find a recruiting trial for Graves Disease?

Use the trial list above filtered by "Recruiting" status, or visit our trial finder at /recruiting to search by condition and state. Always discuss trial participation with your healthcare provider before enrolling.

Is this data current?

Data is sourced from ClinicalTrials.gov and reflects our most recent data pull. Trial status may have changed since then. Always verify current information at ClinicalTrials.gov before making decisions about participation.

Disclaimer: This information is provided for informational purposes only and does not constitute professional advice. Data is sourced from ClinicalTrials.gov (National Library of Medicine). Consult a qualified professional before making decisions based on this data.

Source: ClinicalTrials.gov (NIH/NLM) ClinicalTrials.gov AACT registry · 2026 Trial counts and statuses sourced from ClinicalTrials.gov. Sponsor counts include both industry and federal/academic sponsors.

Verify with NIH →

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page aggregates every registered trial for this condition, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.