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NCT05435547 · ClinicalTrials.gov registry record · Phase 4
Preoperative Corticosteroids in Autoimmune Thyroid Disease
A Phase 4 study of Graves Disease and Hashimoto Disease, sponsored by Indiana University.
- Recruiting
- Registry status
- Phase 4
- Development phase
- 76
- Enrollment target
- 3
- Study locations
NCT05435547: Recruiting Phase 4 study of Graves Disease and Hashimoto Disease, sponsored by Indiana University.
NCT05435547 is a Phase 4 study of Graves Disease and Hashimoto Disease that is actively recruiting participants, run by Indiana University. The registered enrollment target is 76 participants, below the 303-participant average among 11 other Graves Disease trials with a reported enrollment target (75% lower). The trial reports 3 study locations across 1 state. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT05435547, a Phase 4 study of Graves Disease and Hashimoto Disease, is actively recruiting participants, sponsored by Indiana University.
- RECRUITING
- Registry status
- Phase 4
- Development phase
- 76 participants
- Enrollment target
- 3
- Study locations
Study Summary
This study proposes to randomize patients about to undergo surgery for their autoimmune, inflammatory thyroid disease, and determine if a short course of corticosteroids decreases the inflammation of the gland and makes surgery less difficult.
Primary Outcome
This scale is completed by the surgeon to assess the difficulty of a thyroid operation, and includes 4 parameters (vascularity, friability, mobility/fibrosis, and gland size). The scale ranges from 4 points (best outcome) - 20 points (worst outcome). Higher scores indicate a more difficult operation.
Conditions Studied
Interventions
- DRUG Placebo
- DRUG Dexamethasone
Study Locations (3)
Indiana
- IU Health North Hospital - Indianapolis
- IU Health Methodist Hospital - Indianapolis
- IU Health University Hospital - Indianapolis
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 76 participants |
| Start Date | 2023-06-16 |
| Est. Completion | 2026-12-30 |
| Phase | Phase 4 |
What NCT05435547 shows while recruiting
NCT05435547 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 76 participants, a relatively small participant target, below the 303-participant average among 11 other Graves Disease trials with a reported enrollment target (75% lower).
The record links to 2 conditions, with Graves Disease appearing as the primary indexed condition, and to 2 interventions - of which Placebo is the first listed.
NCT05435547 reports a single indexed study location in Indiana.
Frequently Asked Questions
What is clinical trial NCT05435547 about?
NCT05435547 is a clinical study titled "Preoperative Corticosteroids in Autoimmune Thyroid Disease". This study proposes to randomize patients about to undergo surgery for their autoimmune, inflammatory thyroid disease, and determine if a short course of corticosteroids decreases the inflammation of the gland and makes surgery less difficult.
What is the current status of trial NCT05435547?
This trial is currently recruiting. It is a Phase 4 study. The enrollment target is 76 participants. The study started on 2023-06-16. Estimated completion is 2026-12-30.
What conditions does trial NCT05435547 study?
This clinical trial studies the following conditions: Graves Disease, Hashimoto Disease.
What interventions are being tested in trial NCT05435547?
The interventions under investigation include: Placebo (DRUG), Dexamethasone (DRUG).
Who is sponsoring clinical trial NCT05435547?
This trial is sponsored by Indiana University, which has 890 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT05435547 being conducted?
This trial has 3 study locations across Indiana. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
Similar trials for Graves Disease
Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.
Where NCT05435547's enrollment target sits among peer trials
76 7th of 11 higher than 5 of 11 other Graves Disease trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Graves Disease trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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