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Fuchs Endothelial Dystrophy clinical trials
6 of 8 indexed Fuchs Endothelial Dystrophy trials are currently recruiting.
8 US clinical trials · 6 currently recruiting
Fuchs Endothelial Dystrophy is the subject of 8 registered US clinical trials on ClinicalTrials.gov, 6 of them currently open to new participants. 2 are in Phase 3-4 (later-stage) and 2 in Phase 1-2 (earlier-stage). The most active sponsor is Cornea Research Foundation of America, running 1 of these trials.
The research picture
Fuchs Endothelial Dystrophy has 8 registered US clinical trials, 6 of them open to new participants right now, about 75% of the total.
- 6
- recruiting participants now
- 75%
- of trials open to enrollment
- 2
- in Phase 3–4 (later-stage)
- 1
- top sponsor: Cornea Research Foundation of America
Active & Recent Trials
8 total, page 1 of 1
DISCOVER Study: Microscope-integrated Intraoperative OCT Study
The Cleveland Clinic
NCT02423213
A Study to Test the Diagnostic Potential of Brillouin Microscopy for Corneal Ectasia
Massachusetts General Hospital
NCT02118922
Plasma Rich in Growth Factors in Corneal Endothelial Transplantation
University of Miami
NCT06261346
Ripasudil for Enhanced Corneal Clearing Following Descemet Membrane Endothelial Keratoplasty in Fuchs' Dystrophy
Michael D. Straiko, MD
NCT03813056
Descemet Endothelial Thickness Comparison Trial II
Stanford University
NCT05275972
Glanatec(R) for Descemet Stripping in Fuch's Endothelial Dystrophy
Marian Macsai, MD
NCT03249337
Study of Eye Bank Pre-cut Donor Grafts for Endothelial Keratoplasty
Cornea Research Foundation of America
NCT00624221
Netarsudil Use After Descemetorhexis Without Endothelial Keratoplasty
Massachusetts Eye and Ear Infirmary
NCT04057053
Phase Distribution
| Phase | Trial count |
|---|---|
| Phase 1 | 1 |
| Phase 2 | 1 |
| Phase 3 | 1 |
| Phase 4 | 1 |
Top Sponsors
Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.
Reading the Fuchs Endothelial Dystrophy Trial Landscape
8 indexed Fuchs Endothelial Dystrophy studies · 6 recruiting (75%).
Phase mix: 2 late (III/IV) vs 2 early (I/II).
Top sponsor: Cornea Research Foundation of America (1 trial), 7 others listed. 8 shown below, recruiting first.
How to read this condition's trial landscape
That ratio is a useful proxy for activity level: a high share of recruiting studies often signals that research interest is current and that new enrollment opportunities are appearing, while a low share typically means the field is dominated by completed or follow-up work where most participant spots have already been filled. These counts reflect the public registry only and include studies at every stage of design, so they should be read as an index of research attention rather than as a measure of treatment availability.
Phase 1 and Phase 2 studies focus on early safety signals, dosing, and preliminary effect, while Phase 3 studies are typically the larger efficacy and safety trials submitted toward regulatory review, and Phase 4 studies follow approved interventions in real-world use. A condition weighted toward later phases often reflects a mature research pipeline with several interventions already close to or past approval, whereas a heavier early-phase tilt suggests the field is still exploring new mechanisms and candidate approaches.
All figures are derived from the public ClinicalTrials.gov dataset maintained by the National Library of Medicine and are reproduced here for reference. Inclusion of a trial, sponsor, or intervention on this page is neither an endorsement nor a recommendation, eligibility, protocol changes, and site-level status can shift frequently, so always verify current details on ClinicalTrials.gov and consult a qualified healthcare provider before acting on anything you see here.
Frequently Asked Questions
How many clinical trials are there for Fuchs Endothelial Dystrophy?
PlainTrial tracks 8 US clinical trials for Fuchs Endothelial Dystrophy, of which 6 are currently recruiting participants. Data sourced from ClinicalTrials.gov.
How do I find a recruiting trial for Fuchs Endothelial Dystrophy?
Use the trial list above filtered by "Recruiting" status, or visit our trial finder at /recruiting to search by condition and state. Always discuss trial participation with your healthcare provider before enrolling.
Is this data current?
Data is sourced from ClinicalTrials.gov and reflects our most recent data pull. Trial status may have changed since then. Always verify current information at ClinicalTrials.gov before making decisions about participation.
Related
Disclaimer: This information is provided for informational purposes only and does not constitute professional advice. Data is sourced from ClinicalTrials.gov (National Library of Medicine). Consult a qualified professional before making decisions based on this data.
Read our methodology - how this data is sourced, computed, and verified.
Source: ClinicalTrials.gov (NIH/NLM) ClinicalTrials.gov AACT registry · 2026 Trial counts and statuses sourced from ClinicalTrials.gov. Sponsor counts include both industry and federal/academic sponsors.
Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page aggregates every registered trial for this condition, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.