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COMPLETED NA

Study of Eye Bank Pre-cut Donor Grafts for Endothelial Keratoplasty

NCT00624221 · View on ClinicalTrials.gov ↗

Study Summary

Descemet's stripping with endothelial keratoplasty (DSEK) is a cornea-sparing transplant technique that replaces only the diseased endothelial cell layer of the patient's cornea. The DSEK technique requires lamellar dissection of the donor tissue prior to implantation in the patient's eye. The surgeon usually dissects the donor cornea with a microkeratome at the time of surgery. Recently some eye banks have begun to pre-cut the donor graft as an added service. The purpose of this study was to compare outcomes with eye bank pre-cut and surgeon-dissected donor grafts for DSEK.

Interventions

  • PROCEDURE Descemet's stripping endothelial keratoplasty

Study Locations (1)

Indiana

  • Cornea Research Foundation of America — Indianapolis

Trial Details

FieldValue
Enrollment Target 40 participants
Start Date 2006-01
Est. Completion 2007-11
Phase NA

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Full Details on ClinicalTrials.gov ↗

What the Registry Record Tells You About NCT00624221

The ClinicalTrials.gov registry entry for NCT00624221 describes a study currently listed as completed. It is categorized as NA, which is the standard way researchers label where a study sits along the investigational pathway from early safety work through later efficacy and post-marketing evaluation. The registered enrollment target is 40 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is Cornea Research Foundation of America, which has 1 total studies on file at ClinicalTrials.gov, and sponsors are the parties responsible for study design, oversight, and regulatory filings.

The record links to 2 conditions, with Corneal Edema appearing as the primary indexed condition, and to 1 intervention — of which Descemet's stripping endothelial keratoplasty is the first listed. Interventions can include drugs, devices, procedures, behavioral programs, or observational arms, and each is tracked as a separate registry field so that downstream queries can filter accurately. When a trial lists multiple interventions, it usually reflects a multi-arm design or a comparison protocol rather than a single treatment being tested in isolation. The brief summary published in the registry is the clearest source of protocol intent and should be read before drawing conclusions from any sidebar tags.

Geographic footprint matters for practical reasons: NCT00624221 reports 1 study location spanning 1 distinct geographic area — top geographies include Indiana. A larger site network tends to correlate with broader recruitment capacity, but it does not imply anything about study quality, and site-level enrollment status can diverge from the overall registry status shown above. Every data point on this page comes from the public ClinicalTrials.gov dataset and is reproduced here for reference only; it is not a medical recommendation, an endorsement of the sponsor, or an invitation to enroll. Verify current status, eligibility criteria, and contact details directly at ClinicalTrials.gov, and discuss any participation decision with your own healthcare provider.

Frequently Asked Questions

What is clinical trial NCT00624221 about?

NCT00624221 is a clinical study titled "Study of Eye Bank Pre-cut Donor Grafts for Endothelial Keratoplasty". Descemet's stripping with endothelial keratoplasty (DSEK) is a cornea-sparing transplant technique that replaces only the diseased endothelial cell layer of the patient's cornea. The DSEK technique requires lamellar dissection of the donor tissue prior to implantation in the patient's eye. The surge...

What is the current status of trial NCT00624221?

This trial is currently completed. It is a NA study. The enrollment target is 40 participants. The study started on 2006-01. Estimated completion is 2007-11.

What conditions does trial NCT00624221 study?

This clinical trial studies the following conditions: Corneal Edema, Fuchs Endothelial Dystrophy. These conditions were identified from the trial registry and reflect the primary focus areas of the research.

What interventions are being tested in trial NCT00624221?

The interventions under investigation include: Descemet's stripping endothelial keratoplasty (PROCEDURE). Each intervention is being evaluated for safety and efficacy as part of this clinical study.

Who is sponsoring clinical trial NCT00624221?

This trial is sponsored by Cornea Research Foundation of America, which has 1 total clinical trials registered on ClinicalTrials.gov. The sponsor is responsible for the study's design, funding, and regulatory compliance.

Where is trial NCT00624221 being conducted?

This trial has 1 study location across Indiana. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

Related

Data sourced from official U.S. government datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial