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NCT02118922 · ClinicalTrials.gov registry record
A Study to Test the Diagnostic Potential of Brillouin Microscopy for Corneal Ectasia
A clinical trial of Keratoconus and Fuchs Endothelial Dystrophy, sponsored by Massachusetts General Hospital.
- Recruiting
- Registry status
- 168
- Enrollment target
- 1
- Study location
NCT02118922: Recruiting study of Keratoconus and Fuchs Endothelial Dystrophy, sponsored by Massachusetts General Hospital.
NCT02118922 is a study of Keratoconus and Fuchs Endothelial Dystrophy that is actively recruiting participants, run by Massachusetts General Hospital. The registered enrollment target is 168 participants, below the 1,172-participant average among 21 other Keratoconus trials with a reported enrollment target (86% lower). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT02118922, a study of Keratoconus and Fuchs Endothelial Dystrophy, is actively recruiting participants, sponsored by Massachusetts General Hospital.
- RECRUITING
- Registry status
- 168 participants
- Enrollment target
- 1
- Study location
Study Summary
We have developed novel Brillouin microscopy and we are testing its potential for keratoconus and ectasia diagnostics. We plan to perform axial scans of the cornea in human volunteers in order to compare biomechanical properties of Keratoconus vs. Normal corneas and compare biomechanical properties of post-LASIK ectasia vs. normal corneas.
Primary Outcome
Patients will be measured one time only at their imaging session
Conditions Studied
Interventions
- PROCEDURE Brillouin imaging
Study Locations (1)
Massachusetts
- Massachusetts General Hospital - Boston
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 168 participants |
| Start Date | 2013-06 |
| Est. Completion | 2026-09 |
What NCT02118922 shows while recruiting
NCT02118922 is an observational study that tracks outcomes without assigning an intervention. The registered 168 participants enrollment target is mid-sized for trials with a published cap, below the 1,172-participant average among 21 other Keratoconus trials with a reported enrollment target (86% lower).
The record links to 4 conditions, with Keratoconus appearing as the primary indexed condition, and to 1 intervention - of which Brillouin imaging is the first listed.
NCT02118922 reports a single indexed study location in Massachusetts.
Frequently Asked Questions
What is clinical trial NCT02118922 about?
NCT02118922 is a clinical study titled "A Study to Test the Diagnostic Potential of Brillouin Microscopy for Corneal Ectasia". We have developed novel Brillouin microscopy and we are testing its potential for keratoconus and ectasia diagnostics. We plan to perform axial scans of the cornea in human volunteers in order to compare biomechanical properties of Keratoconus vs. Normal corneas and compare biomechanical properties ...
What is the current status of trial NCT02118922?
This trial is currently recruiting. The enrollment target is 168 participants. The study started on 2013-06. Estimated completion is 2026-09.
What conditions does trial NCT02118922 study?
This clinical trial studies the following conditions: Keratoconus, Fuchs Endothelial Dystrophy, Ectasia, Crosslinking.
What interventions are being tested in trial NCT02118922?
The interventions under investigation include: Brillouin imaging (PROCEDURE).
Who is sponsoring clinical trial NCT02118922?
This trial is sponsored by Massachusetts General Hospital, which has 2,032 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT02118922 being conducted?
This trial has 1 study location across Massachusetts. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
Similar trials for Keratoconus
Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.
Where NCT02118922's enrollment target sits among peer trials
168 13th of 21 higher than 9 of 21 other Keratoconus trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Keratoconus trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
-
OCT in Diagnosis of Irregular Corneas
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-
Comparison of Epi-ON Corneal Collagen Crosslinking Performed Using an 18-Minute UVA Exposure vs. a 24-Minute UVA Exposure on Eyes With Ectatic Corneal Diseases
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Collagen Cross-linking in Keratoconus
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Corneal Elastography and Patient Specific Modeling
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Compassionate Use Study of Epi-ON Corneal Collagen Crosslinking Performed Using UVA Exposure on Eyes With Ectatic Corneal Diseases for Subjects With Down Syndrome
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-
Safety and Effectiveness of the PXL-Platinum 330 System for Cornea Crosslinking in Eyes With Cornea Thinning
RECRUITING · Phase 2
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